SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vil'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDT_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 11 LEU A 189
HIS A 148
SER A 105
PHE A 104
GLU A 402
None
SA0  A 507 (-4.0A)
None
None
SA0  A 507 (-2.4A)
1.39A 1fdtA-3vilA:
undetectable
1fdtA-3vilA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 6 ILE A 400
ASN A 335
ASN A 192
THR A 145
None
SA0  A 507 ( 4.9A)
SA0  A 507 (-3.4A)
None
1.24A 1h7xA-3vilA:
6.4
1h7xA-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 6 ILE A 400
ASN A 335
SER A 251
ASN A 192
None
SA0  A 507 ( 4.9A)
None
SA0  A 507 (-3.4A)
1.24A 1h7xA-3vilA:
6.4
1h7xA-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 6 ILE A 400
ASN A 335
SER A 251
ASN A 192
THR A 145
None
SA0  A 507 ( 4.9A)
None
SA0  A 507 (-3.4A)
None
1.44A 1h7xB-3vilA:
6.4
1h7xB-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 6 ILE A 400
ASN A 335
ASN A 192
THR A 145
None
SA0  A 507 ( 4.9A)
SA0  A 507 (-3.4A)
None
1.24A 1h7xC-3vilA:
6.3
1h7xC-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 6 ILE A 400
ASN A 335
SER A 251
ASN A 192
None
SA0  A 507 ( 4.9A)
None
SA0  A 507 (-3.4A)
1.24A 1h7xC-3vilA:
6.3
1h7xC-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 6 ILE A 400
ASN A 335
ASN A 192
THR A 145
None
SA0  A 507 ( 4.9A)
SA0  A 507 (-3.4A)
None
1.24A 1h7xD-3vilA:
8.3
1h7xD-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 6 ILE A 400
ASN A 335
SER A 251
ASN A 192
None
SA0  A 507 ( 4.9A)
None
SA0  A 507 (-3.4A)
1.22A 1h7xD-3vilA:
8.3
1h7xD-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 6 TYR A 292
ILE A 285
TYR A 281
GLY A 279
None
1.01A 1maaB-3vilA:
undetectable
1maaD-3vilA:
undetectable
1maaB-3vilA:
22.60
1maaD-3vilA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 12 LEU A 131
TYR A 127
LEU A  94
LEU A 446
TYR A 102
None
1.39A 1p33A-3vilA:
2.1
1p33A-3vilA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 12 ILE A 334
GLY A 333
HIS A 229
VAL A 398
LEU A 386
None
1.03A 1vptA-3vilA:
undetectable
1vptA-3vilA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 7 ALA A 443
THR A 442
ARG A 103
TYR A 102
None
0.92A 2ql8A-3vilA:
undetectable
2ql8B-3vilA:
undetectable
2ql8A-3vilA:
15.04
2ql8B-3vilA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 7 LEU A  37
GLU A 141
MET A 427
MET A 143
None
1.24A 2w8yA-3vilA:
undetectable
2w8yA-3vilA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 11 SER A 445
ALA A  39
LEU A 131
LEU A 135
LEU A  94
None
1.11A 2xn5A-3vilA:
undetectable
2xn5A-3vilA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 TRP A 256
VAL A 295
ARG A 302
None
0.84A 3b0wA-3vilA:
undetectable
3b0wA-3vilA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 12 ALA A 167
ILE A 232
THR A 328
ILE A 250
ILE A 226
None
1.18A 3clbB-3vilA:
undetectable
3clbB-3vilA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 12 LEU A 252
VAL A 248
GLY A 249
GLY A 333
THR A 190
None
1.38A 3dh0A-3vilA:
undetectable
3dh0A-3vilA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 12 LEU A  37
GLY A 440
VAL A 398
LEU A 428
PHE A  31
None
1.11A 3h52C-3vilA:
undetectable
3h52C-3vilA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 12 LEU A 483
TYR A 463
TYR A 441
GLY A  38
ALA A  39
None
1.26A 3n8xA-3vilA:
undetectable
3n8xA-3vilA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 5 LEU A 155
SER A 170
LEU A 151
PRO A 152
None
1.31A 3onnA-3vilA:
undetectable
3onnA-3vilA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 TYR A 128
GLY A 124
ASP A 123
None
0.65A 3ou6C-3vilA:
undetectable
3ou6C-3vilA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 TYR A  84
ASP A  82
ASP A  78
None
0.86A 3ou7B-3vilA:
undetectable
3ou7B-3vilA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 5 LEU A 483
ILE A 492
PRO A 493
PHE A 496
None
0.95A 3s3vA-3vilA:
undetectable
3s3vA-3vilA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 6 HIS A  65
ASP A 466
ASP A  78
GLU A 468
None
1.29A 3vywA-3vilA:
undetectable
3vywA-3vilA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 7 GLY A  48
ASP A  78
GLY A  77
HIS A  65
None
0.92A 4c5nA-3vilA:
undetectable
4c5nA-3vilA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 8 GLY A  48
ASP A  78
GLY A  77
HIS A  65
None
0.84A 4c5nC-3vilA:
undetectable
4c5nC-3vilA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 12 LEU A 189
GLY A 440
GLN A 100
ARG A 490
ILE A 439
None
1.04A 4djeA-3vilA:
10.3
4djeA-3vilA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 8 LEU A 166
SER A 170
TRP A 108
ASP A 150
None
0.92A 4drjB-3vilA:
undetectable
4drjB-3vilA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 7 GLU A 323
GLU A 320
GLY A 290
ARG A 326
None
0.91A 4fgzA-3vilA:
undetectable
4fgzA-3vilA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 ILE A 140
MET A 487
ARG A 490
None
0.89A 4lnwA-3vilA:
undetectable
4lnwA-3vilA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 ILE A 140
MET A 487
ARG A 490
None
0.88A 4lnxA-3vilA:
undetectable
4lnxA-3vilA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 ASP A 150
TRP A 444
SER A 105
None
SA0  A 507 (-3.7A)
None
1.02A 4lrhB-3vilA:
undetectable
4lrhB-3vilA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 ASP A 150
TRP A 444
SER A 105
None
SA0  A 507 (-3.7A)
None
1.10A 4lrhF-3vilA:
undetectable
4lrhF-3vilA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 SER A 479
TYR A 420
ASP A 448
None
0.89A 4rp8C-3vilA:
undetectable
4rp8C-3vilA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 12 TYR A  87
TYR A  44
ASP A  82
ALA A  80
TYR A 456
None
1.31A 4ymgB-3vilA:
undetectable
4ymgB-3vilA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 ASP A 218
ARG A 353
TYR A 219
None
0.93A 5a7mA-3vilA:
4.7
5a7mA-3vilA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 ASP A 218
ARG A 353
TYR A 219
None
0.92A 5a7mB-3vilA:
5.4
5a7mB-3vilA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 5 PHE A 317
LEU A 296
GLY A 279
ILE A 325
None
0.99A 5ik1A-3vilA:
undetectable
5ik1A-3vilA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O45_B_CCSB13_0
(PHE-MEA-9KK-SAR-ASP-
VAL-MEA-TYR-SAR-TRP-
TYR-LEU-CCS-GLY-NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 9 ASP A 126
ASN A 180
VAL A 176
TYR A 128
GLY A 124
None
NA  A 510 (-3.6A)
NA  A 510 ( 4.4A)
None
None
1.44A 5o45A-3vilA:
0.0
5o45B-3vilA:
undetectable
5o45A-3vilA:
15.61
5o45B-3vilA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 6 GLU A 402
ARG A 103
TYR A 337
SER A 193
SA0  A 507 (-2.4A)
None
SA0  A 507 (-4.1A)
SA0  A 507 (-3.5A)
1.00A 5phhA-3vilA:
undetectable
5phhA-3vilA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 GLN A 316
ILE A 285
HIS A 229
None
0.70A 5z12B-3vilA:
undetectable
5z12B-3vilA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
3 / 3 GLU A 321
ASP A 291
PRO A 284
None
0.79A 6berA-3vilA:
undetectable
6berA-3vilA:
5.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
4 / 6 GLY A 415
ASP A 413
SER A 479
ARG A 416
None
1.11A 6dwdA-3vilA:
undetectable
6dwdC-3vilA:
undetectable
6dwdA-3vilA:
23.18
6dwdC-3vilA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis)
5 / 9 MET A 447
SER A 445
ILE A 140
ALA A  99
LEU A  97
None
1.39A 6hqbB-3vilA:
undetectable
6hqbB-3vilA:
12.89