SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vis'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 10 ALA A 160
LEU A 147
LEU A 143
ARG A 182
ILE A  81
 None
 1.13A 1a52A-3visA:
undetectable		 1a52A-3visA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 10 ALA A 160
LEU A 147
LEU A 143
ARG A 182
ILE A  81
 None
 1.16A 1a52B-3visA:
undetectable		 1a52B-3visA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 9 ALA A 160
LEU A 147
LEU A 143
ARG A 182
ILE A  81
 None
 1.18A 1ereA-3visA:
undetectable		 1ereA-3visA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 9 ALA A 160
LEU A 147
LEU A 143
ARG A 182
ILE A  81
 None
 1.20A 1ereB-3visA:
undetectable		 1ereB-3visA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 9 ALA A 160
LEU A 147
LEU A 143
ARG A 182
ILE A  81
 None
 1.20A 1ereC-3visA:
undetectable		 1ereC-3visA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 9 ALA A 160
LEU A 147
LEU A 143
ARG A 182
ILE A  81
 None
 1.21A 1ereD-3visA:
undetectable		 1ereD-3visA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 12 ALA A  94
LEU A 143
ALA A 142
VAL A 205
ILE A 203
 None
 1.01A 1fm6U-3visA:
undetectable		 1fm6U-3visA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 12 TRP A 108
LEU A 242
ILE A 257
ILE A 106
LEU A 109
 None
 1.23A 1kyvA-3visA:
3.5
1kyvE-3visA:
3.5		 1kyvA-3visA:
19.61
1kyvE-3visA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 12 ILE A 106
LEU A 109
TRP A 108
LEU A 242
ILE A 257
 None
 1.22A 1kyvB-3visA:
3.5
1kyvC-3visA:
3.5		 1kyvB-3visA:
19.61
1kyvC-3visA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 12 ILE A 106
LEU A 109
TRP A 108
LEU A 242
ILE A 257
 None
 1.24A 1kyvC-3visA:
3.4
1kyvD-3visA:
3.6		 1kyvC-3visA:
19.61
1kyvD-3visA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 12 ILE A 106
LEU A 109
TRP A 108
LEU A 242
ILE A 257
 None
 1.20A 1kyvD-3visA:
3.6
1kyvE-3visA:
3.5		 1kyvD-3visA:
19.61
1kyvE-3visA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 10 ALA A 160
LEU A 147
LEU A 143
ARG A 182
ILE A  81
 None
 1.21A 1pcgA-3visA:
undetectable		 1pcgA-3visA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3vis ESTERASE
(Thermobifida
alba) 		3 / 3 ASP A 290
LEU A 242
HIS A 116
 None
 0.78A 1qknA-3visA:
undetectable		 1qknA-3visA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 10 ALA A 160
LEU A 147
LEU A 143
ARG A 182
ILE A  81
 None
 1.20A 1qkuA-3visA:
undetectable		 1qkuA-3visA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 10 ALA A 160
LEU A 147
LEU A 143
ARG A 182
ILE A  81
 None
 1.20A 1qkuB-3visA:
undetectable		 1qkuB-3visA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 10 ALA A 160
LEU A 147
LEU A 143
ARG A 182
ILE A  81
 None
 1.20A 1qkuC-3visA:
undetectable		 1qkuC-3visA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3vis ESTERASE
(Thermobifida
alba) 		6 / 12 GLY A 171
SER A 224
ILE A 209
GLY A 167
GLY A 172
PRO A 190
 None
 1.39A 1uakA-3visA:
undetectable		 1uakA-3visA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 12 GLY A 173
GLY A 174
VAL A 165
LEU A 139
LEU A 185
 None
 1.17A 1ya4B-3visA:
14.0		 1ya4B-3visA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 3vis ESTERASE
(Thermobifida
alba) 		4 / 8 LEU A 242
ASN A 251
HIS A 168
ALA A 212
 None
 0.99A 2bnnA-3visA:
undetectable
2bnnB-3visA:
undetectable		 2bnnA-3visA:
21.93
2bnnB-3visA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 10 TYR A  82
THR A 102
GLY A  79
THR A  80
ALA A 122
 None
 1.32A 2coiA-3visA:
undetectable
2coiB-3visA:
undetectable		 2coiA-3visA:
19.59
2coiB-3visA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 10 TYR A  82
THR A 102
GLY A  79
THR A  80
ALA A 122
 None
 1.31A 2coiA-3visA:
undetectable
2coiB-3visA:
undetectable		 2coiA-3visA:
19.59
2coiB-3visA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 11 TYR A  82
THR A 102
GLY A  79
THR A  80
ALA A 122
 None
 1.38A 2cojA-3visA:
undetectable
2cojB-3visA:
undetectable		 2cojA-3visA:
19.59
2cojB-3visA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 12 VAL A 220
ASN A 254
ILE A 257
ILE A 210
HIS A 168
 None
 1.02A 2ft9A-3visA:
undetectable		 2ft9A-3visA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 12 ALA A 160
LEU A 147
LEU A 143
ARG A 182
ILE A  81
 None
 1.21A 2yjaB-3visA:
undetectable		 2yjaB-3visA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3vis ESTERASE
(Thermobifida
alba) 		4 / 7 ALA A 245
ASN A 254
PRO A 250
ALA A 249
 None
 1.11A 2zgwA-3visA:
undetectable		 2zgwA-3visA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3vis ESTERASE
(Thermobifida
alba) 		4 / 6 ALA A 245
ASN A 254
PRO A 250
ALA A 249
 None
 1.15A 2zgwB-3visA:
undetectable		 2zgwB-3visA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 11 ALA A  92
GLY A  91
TYR A  90
ALA A 150
TYR A 145
 None
 1.26A 3qxyB-3visA:
undetectable
3qxyQ-3visA:
undetectable		 3qxyB-3visA:
20.26
3qxyQ-3visA:
5.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 3vis ESTERASE
(Thermobifida
alba) 		4 / 6 GLY A 117
ARG A 162
GLU A  44
ARG A 274
 None
 1.17A 4bqfA-3visA:
3.2		 4bqfA-3visA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 12 GLY A 167
ILE A 113
GLY A 258
ILE A  95
ILE A 210
 None
 0.99A 4q5mA-3visA:
undetectable		 4q5mA-3visA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3vis ESTERASE
(Thermobifida
alba) 		4 / 8 THR A 102
GLY A  78
GLY A  77
ASP A 130
 None
 0.84A 4qvvK-3visA:
undetectable
4qvvL-3visA:
undetectable		 4qvvK-3visA:
22.07
4qvvL-3visA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3vis ESTERASE
(Thermobifida
alba) 		4 / 8 THR A 102
GLY A  78
GLY A  77
ASP A 130
 None
 0.84A 4qvvY-3visA:
undetectable
4qvvZ-3visA:
undetectable		 4qvvY-3visA:
22.07
4qvvZ-3visA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 3vis ESTERASE
(Thermobifida
alba) 		4 / 7 ILE A 210
ALA A 249
ASN A 254
ILE A 257
 None
 0.83A 4y03A-3visA:
undetectable		 4y03A-3visA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3vis ESTERASE
(Thermobifida
alba) 		4 / 6 SER A 219
GLY A 167
ARG A 135
GLY A 173
 None
 0.95A 5cdnT-3visA:
undetectable
5cdnU-3visA:
4.1		 5cdnT-3visA:
22.92
5cdnU-3visA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_C_MMZC503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 3vis ESTERASE
(Thermobifida
alba) 		4 / 4 TYR A  83
ASN A 156
SER A 152
SER A 151
 None
 1.48A 5gsnC-3visA:
1.2		 5gsnC-3visA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3vis ESTERASE
(Thermobifida
alba) 		5 / 12 ILE A 113
GLY A 110
ASP A 270
ILE A 158
MET A 146
 None
 1.20A 5igwA-3visA:
undetectable		 5igwA-3visA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3vis ESTERASE
(Thermobifida
alba) 		6 / 11 LEU A 178
ILE A 203
GLY A 172
LEU A 185
THR A 207
VAL A 165
 None
 1.32A 5twjD-3visA:
undetectable		 5twjD-3visA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3vis ESTERASE
(Thermobifida
alba) 		6 / 11 LEU A 178
ILE A 203
GLY A 174
LEU A 185
THR A 207
VAL A 165
 None
 1.00A 5twjD-3visA:
undetectable		 5twjD-3visA:
23.49