SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vj6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBM_B_RTLB951_1 (PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN))	3vj6	H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-37 ALPHA CHAIN (Mus musculus)	4 / 4	THR A 178 LEU A 179 VAL A 28 LEU A 5	None	1.05A	1fbmB-3vj6A: undetectable	1fbmB-3vj6A: 10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3A_A_TEPA1435_1 (CHITINASE)	3vj6	H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-37 ALPHA CHAIN (Mus musculus)	3 / 3	TRP A 167 GLU A 63 TYR A 59	None	0.82A	2a3aA-3vj6A: undetectable	2a3aA-3vj6A: 20.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5J6H_A_NCAA402_0 (H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, Q10 ALPHA CHAIN)	3vj6	H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-37 ALPHA CHAIN (Mus musculus)	3 / 3	PRO A 47 ARG A 48 GLU A 53	None	0.56A	5j6hA-3vj6A: 34.2	5j6hA-3vj6A: 78.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L6E_B_ACTB401_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14)	3vj6	H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-37 ALPHA CHAIN (Mus musculus)	4 / 6	ARG A 79 LEU A 78 ARG A 14 ARG A 75	None	1.28A	5l6eA-3vj6A: undetectable 5l6eB-3vj6A: undetectable	5l6eA-3vj6A: 23.79 5l6eB-3vj6A: 24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F6S_A_CXQA507_1 (ENVELOPE GLYCOPROTEIN,ENVELOP E GLYCOPROTEIN,GP1 ENVELOPE GLYCOPROTEIN)	3vj6	H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-37 ALPHA CHAIN (Mus musculus)	4 / 5	ALA A 135 TYR A 123 GLN A 141 ILE A 142	None	1.27A	6f6sA-3vj6A: undetectable 6f6sB-3vj6A: 0.0	6f6sA-3vj6A: 14.80 6f6sB-3vj6A: 14.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FBM_B_RTLB951_1","PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN)","3vj6","H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-37 ALPHA CHAIN","Mus musculus",4,"THR A 178;LEU A 179;VAL A  28;LEU A   5","None","1.05A","1fbmB-3vj6A:undetectable","1fbmB-3vj6A:10.95"],["2A3A_A_TEPA1435_1","CHITINASE","3vj6","H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-37 ALPHA CHAIN","Mus musculus",3,"TRP A 167;GLU A  63;TYR A  59","None","0.82A","2a3aA-3vj6A:undetectable","2a3aA-3vj6A:20.37"],["5J6H_A_NCAA402_0","H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, Q10 ALPHA CHAIN","3vj6","H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-37 ALPHA CHAIN","Mus musculus",3,"PRO A  47;ARG A  48;GLU A  53","None","0.56A","5j6hA-3vj6A:34.2","5j6hA-3vj6A:78.06"],["5L6E_B_ACTB401_0","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT;N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","3vj6","H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-37 ALPHA CHAIN","Mus musculus",4,"ARG A  79;LEU A  78;ARG A  14;ARG A  75","None","1.28A","5l6eA-3vj6A:undetectable;5l6eB-3vj6A:undetectable","5l6eA-3vj6A:23.79;5l6eB-3vj6A:24.55"],["6F6S_A_CXQA507_1","ENVELOPE GLYCOPROTEIN,ENVELOPE GLYCOPROTEIN,GP1;ENVELOPE GLYCOPROTEIN","3vj6","H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-37 ALPHA CHAIN","Mus musculus",4,"ALA A 135;TYR A 123;GLN A 141;ILE A 142","None","1.27A","6f6sA-3vj6A:undetectable;6f6sB-3vj6A:0.0","6f6sA-3vj6A:14.80;6f6sB-3vj6A:14.91"]]