SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vjz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OPX_A_DXCA1003_0 (ALDEHYDE DEHYDROGENASE A)	3vjz	PUTATIVE UNCHARACTERIZED PROTEIN (Neisseria meningitidis)	4 / 5	ILE A 89 LEU A 148 ASP A 44 PHE A 159	None	1.06A	2opxA-3vjzA: undetectable	2opxA-3vjzA: 15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3003_1 (TRANSCRIPTIONAL REGULATOR TCAR)	3vjz	PUTATIVE UNCHARACTERIZED PROTEIN (Neisseria meningitidis)	4 / 6	ILE A 89 VAL A 92 LEU A 96 LEU A 80	None	0.79A	3kp6A-3vjzA: undetectable 3kp6B-3vjzA: undetectable	3kp6A-3vjzA: 24.26 3kp6B-3vjzA: 24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_D_SAMD300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	3vjz	PUTATIVE UNCHARACTERIZED PROTEIN (Neisseria meningitidis)	5 / 12	TYR A 53 GLU A 111 ALA A 68 ASP A 119 LEU A 123	None	1.44A	3ou6D-3vjzA: undetectable	3ou6D-3vjzA: 24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0O_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	3vjz	PUTATIVE UNCHARACTERIZED PROTEIN (Neisseria meningitidis)	3 / 3	ALA A 31 GLN A 45 THR A 49	None	0.57A	5n0oA-3vjzA: undetectable	5n0oA-3vjzA: 19.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OPX_A_DXCA1003_0","ALDEHYDE DEHYDROGENASE A","3vjz","PUTATIVE UNCHARACTERIZED PROTEIN","Neisseria meningitidis",4,"ILE A  89;LEU A 148;ASP A  44;PHE A 159","None","1.06A","2opxA-3vjzA:undetectable","2opxA-3vjzA:15.00"],["3KP6_B_SALB3003_1","TRANSCRIPTIONAL REGULATOR TCAR;TRANSCRIPTIONAL REGULATOR TCAR","3vjz","PUTATIVE UNCHARACTERIZED PROTEIN","Neisseria meningitidis",4,"ILE A  89;VAL A  92;LEU A  96;LEU A  80","None","0.79A","3kp6A-3vjzA:undetectable;3kp6B-3vjzA:undetectable","3kp6A-3vjzA:24.26;3kp6B-3vjzA:24.26"],["3OU6_D_SAMD300_0","SAM-DEPENDENT METHYLTRANSFERASE","3vjz","PUTATIVE UNCHARACTERIZED PROTEIN","Neisseria meningitidis",5,"TYR A  53;GLU A 111;ALA A  68;ASP A 119;LEU A 123","None","1.44A","3ou6D-3vjzA:undetectable","3ou6D-3vjzA:24.17"],["5N0O_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","3vjz","PUTATIVE UNCHARACTERIZED PROTEIN","Neisseria meningitidis",3,"ALA A  31;GLN A  45;THR A  49","None","0.57A","5n0oA-3vjzA:undetectable","5n0oA-3vjzA:19.20"]]