SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vk9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 3vk9 GLUTATHIONE
S-TRANSFERASE DELTA
(Bombyx
mori) 		4 / 7 THR A  20
ALA A  16
SER A 164
VAL A 156
 None
 0.70A 1tyrB-3vk9A:
undetectable		 1tyrB-3vk9A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 3vk9 GLUTATHIONE
S-TRANSFERASE DELTA
(Bombyx
mori) 		5 / 12 LEU A  24
LEU A  84
ILE A   3
LEU A  99
VAL A  95
 None
 1.21A 2hrcB-3vk9A:
undetectable		 2hrcB-3vk9A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 3vk9 GLUTATHIONE
S-TRANSFERASE DELTA
(Bombyx
mori) 		4 / 6 THR A  53
VAL A  54
CYH A  14
SER A  11
 None
 1.20A 3b6rB-3vk9A:
undetectable		 3b6rB-3vk9A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3vk9 GLUTATHIONE
S-TRANSFERASE DELTA
(Bombyx
mori) 		5 / 12 LEU A   5
ALA A  69
THR A  72
VAL A 156
VAL A  17
 None
 0.95A 3rukA-3vk9A:
undetectable		 3rukA-3vk9A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 3vk9 GLUTATHIONE
S-TRANSFERASE DELTA
(Bombyx
mori) 		5 / 9 LEU A  74
SER A 160
LEU A 159
VAL A  17
THR A  20
 None
 1.14A 4x3mB-3vk9A:
undetectable		 4x3mB-3vk9A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 3vk9 GLUTATHIONE
S-TRANSFERASE DELTA
(Bombyx
mori) 		4 / 5 VAL A 156
THR A  72
ASP A  96
LEU A  99
 None
 1.23A 5m0iB-3vk9A:
undetectable		 5m0iB-3vk9A:
23.48