SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vlb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 3vlb XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE A
(Aspergillus
aculeatus) 		5 / 11 LEU B 214
ALA B 212
ALA B 100
SER B  66
THR B 204
 None
 1.22A 1tz8A-3vlbB:
undetectable
1tz8B-3vlbB:
undetectable		 1tz8A-3vlbB:
19.20
1tz8B-3vlbB:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3vlb XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE A
(Aspergillus
aculeatus) 		4 / 5 LEU B 127
PRO B 206
ALA B 100
ILE B  98
 None
 1.01A 2aofB-3vlbB:
undetectable		 2aofB-3vlbB:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 3vlb XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE A
(Aspergillus
aculeatus) 		4 / 6 ASP B 187
TYR B 163
PHE B 182
LEU B 108
 None
 0.96A 2w98A-3vlbB:
undetectable
2w98B-3vlbB:
undetectable		 2w98A-3vlbB:
19.94
2w98B-3vlbB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3vlb XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE A
(Aspergillus
aculeatus) 		5 / 12 PHE B  74
PHE B  21
ALA B  70
ALA B 202
LEU B 178
 None
 1.24A 2x2nB-3vlbB:
undetectable		 2x2nB-3vlbB:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3vlb XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE A
(Aspergillus
aculeatus) 		5 / 12 THR B  39
ALA B  70
GLY B 203
THR B 204
PHE B  21
 None
 1.00A 2y7hB-3vlbB:
undetectable		 2y7hB-3vlbB:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3vlb XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE A
(Aspergillus
aculeatus) 		5 / 12 THR B  39
ALA B  70
GLY B 203
THR B 204
PHE B  21
 None
 1.00A 2y7hC-3vlbB:
undetectable		 2y7hC-3vlbB:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_C_MTXC201_1
(DIHYDROFOLATE
REDUCTASE)		 3vlb XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE A
(Aspergillus
aculeatus) 		5 / 11 ALA B 146
ASP B 180
SER B 220
ILE B 221
LEU B 200
 None
 1.24A 4qi9C-3vlbB:
undetectable		 4qi9C-3vlbB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3vlb XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE A
(Aspergillus
aculeatus) 		5 / 12 ASP B 101
ALA B 130
PHE B 207
GLY B 209
SER B 210
 None
 1.11A 5hfjF-3vlbB:
undetectable		 5hfjF-3vlbB:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 3vlb XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE A
(Aspergillus
aculeatus) 		4 / 5 ILE B  82
GLN B  78
THR B  77
THR B 183
 None
 1.06A 6f3mD-3vlbB:
undetectable		 6f3mD-3vlbB:
18.67