SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vm5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		7 / 12 TYR A  62
LEU A 162
LEU A 165
ASP A 197
ALA A 198
HIS A 299
ASP A 300
 None
 0.60A 1dedA-3vm5A:
27.5		 1dedA-3vm5A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		8 / 12 TYR A  62
LEU A 165
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
None
CL  A 507 (-3.9A)
None
None
None
None
None
 0.75A 1dedB-3vm5A:
24.9		 1dedB-3vm5A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 6 LEU A 170
HIS A 101
LEU A  69
LEU A  79
 None
 0.94A 1errA-3vm5A:
undetectable		 1errA-3vm5A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		5 / 12 TYR A  62
GLN A  63
HIS A 299
ASP A 300
TRP A  58
 None
 1.00A 1eswA-3vm5A:
13.8		 1eswA-3vm5A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 5 THR A 111
PHE A 119
GLU A 109
GLY A 108
 None
 1.25A 1icrA-3vm5A:
undetectable
1icrB-3vm5A:
undetectable		 1icrA-3vm5A:
17.03
1icrB-3vm5A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 5 GLU A 109
GLY A 108
THR A 111
PHE A 119
 None
 1.28A 1icrA-3vm5A:
undetectable
1icrB-3vm5A:
undetectable		 1icrA-3vm5A:
17.03
1icrB-3vm5A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 6 THR A 111
PHE A 119
GLU A 109
GLY A 108
 None
 1.16A 1icuC-3vm5A:
undetectable
1icuD-3vm5A:
undetectable		 1icuC-3vm5A:
17.03
1icuD-3vm5A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 5 THR A 111
PHE A 119
GLU A 109
GLY A 108
 None
 1.22A 1icvC-3vm5A:
undetectable
1icvD-3vm5A:
undetectable		 1icvC-3vm5A:
17.03
1icvD-3vm5A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 5 GLU A 109
GLY A 108
THR A 111
PHE A 119
 None
 1.20A 1icvC-3vm5A:
undetectable
1icvD-3vm5A:
undetectable		 1icvC-3vm5A:
17.03
1icvD-3vm5A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		5 / 12 HIS A 331
ILE A 428
ALA A 324
TYR A 327
ARG A 399
 None
 1.43A 1ki7B-3vm5A:
undetectable		 1ki7B-3vm5A:
19.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		9 / 12 TRP A  58
GLN A  63
HIS A 101
VAL A 163
GLY A 164
ALA A 198
GLU A 233
ILE A 235
ASP A 300
 None
 0.46A 1kxhA-3vm5A:
49.8		 1kxhA-3vm5A:
45.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		6 / 12 TRP A  58
HIS A 101
GLY A 104
ALA A 198
GLU A 233
ASP A 300
 None
 1.15A 1kxhA-3vm5A:
49.8		 1kxhA-3vm5A:
45.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		3 / 3 TRP A  59
TYR A  62
LEU A 165
 None
 0.25A 1kxhA-3vm5A:
49.8		 1kxhA-3vm5A:
45.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		9 / 12 TRP A  58
TYR A  62
HIS A 101
ARG A 195
ASP A 197
LYS A 200
GLU A 233
HIS A 299
ASP A 300
 None
None
None
CL  A 507 (-3.9A)
None
None
None
None
None
 0.74A 1mxdA-3vm5A:
28.8		 1mxdA-3vm5A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 7 HIS A 201
TYR A 247
LEU A 207
GLN A 232
 None
 1.05A 1qzrA-3vm5A:
undetectable		 1qzrA-3vm5A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 7 HIS A 201
TYR A 247
LEU A 207
GLN A 232
 None
 1.02A 1qzrB-3vm5A:
undetectable		 1qzrB-3vm5A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		3 / 3 PRO A 130
ASP A 135
ASP A 125
 None
 0.77A 1sqfA-3vm5A:
undetectable		 1sqfA-3vm5A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		5 / 12 THR A 296
THR A 336
GLY A 326
ASP A 486
ILE A 454
 None
 0.95A 2b25A-3vm5A:
undetectable		 2b25A-3vm5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		5 / 12 ILE A  24
ALA A  25
ARG A  85
ILE A 373
HIS A 387
 None
 1.12A 2h77A-3vm5A:
undetectable		 2h77A-3vm5A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		6 / 11 TYR A  62
GLN A  63
ASP A 197
HIS A 299
ASP A 300
TRP A  58
 None
 0.95A 2owcA-3vm5A:
13.3		 2owcA-3vm5A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		6 / 11 TYR A  62
GLN A  63
ASP A 197
HIS A 299
ASP A 300
TRP A  58
 None
 0.95A 2owwA-3vm5A:
13.2		 2owwA-3vm5A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 8 VAL A 325
TYR A 321
VAL A  14
VAL A 396
 None
 1.25A 2y05A-3vm5A:
undetectable
2y05B-3vm5A:
undetectable		 2y05A-3vm5A:
19.25
2y05B-3vm5A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 507 (-3.9A)
None
None
None
None
None
 0.61A 3aicA-3vm5A:
5.1		 3aicA-3vm5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 507 (-3.9A)
None
None
None
None
None
 0.61A 3aicB-3vm5A:
10.4		 3aicB-3vm5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		7 / 12 ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
TYR A  62
 CL  A 507 (-3.9A)
None
None
None
None
None
None
 0.66A 3aicC-3vm5A:
11.3		 3aicC-3vm5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 507 (-3.9A)
None
None
None
None
None
 0.67A 3aicD-3vm5A:
11.3		 3aicD-3vm5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 507 (-3.9A)
None
None
None
None
None
 0.63A 3aicE-3vm5A:
11.1		 3aicE-3vm5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 507 (-3.9A)
None
None
None
None
None
 0.65A 3aicF-3vm5A:
11.1		 3aicF-3vm5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 507 (-3.9A)
None
None
None
None
None
 0.62A 3aicG-3vm5A:
11.1		 3aicG-3vm5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 507 (-3.9A)
None
None
None
None
None
 0.65A 3aicH-3vm5A:
11.1		 3aicH-3vm5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		5 / 10 ILE A  24
ILE A  42
VAL A  95
GLY A 193
ARG A   7
 None
 1.09A 3elzC-3vm5A:
undetectable		 3elzC-3vm5A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		5 / 12 ILE A  24
ALA A  25
ARG A  85
ILE A 373
HIS A 387
 None
 1.14A 4lnwA-3vm5A:
undetectable		 4lnwA-3vm5A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		5 / 12 ILE A  24
ALA A  25
ARG A  85
ILE A 373
HIS A 387
 None
 1.13A 4lnxA-3vm5A:
undetectable		 4lnxA-3vm5A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		5 / 12 ARG A 195
ASP A 197
GLU A 233
HIS A 299
ASP A 300
 CL  A 507 (-3.9A)
None
None
None
None
 0.45A 5csyB-3vm5A:
5.3		 5csyB-3vm5A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		3 / 3 ASP A 486
ASN A 431
PHE A 478
 None
 0.75A 5dsgB-3vm5A:
undetectable		 5dsgB-3vm5A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 6 PHE A 488
PRO A 487
MET A 323
LEU A 437
 None
 1.47A 5dzka-3vm5A:
2.5
5dzko-3vm5A:
undetectable		 5dzka-3vm5A:
16.19
5dzko-3vm5A:
1.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 6 PHE A 430
MET A 395
ILE A 454
ASP A 452
 None
 1.30A 5iwuA-3vm5A:
undetectable		 5iwuA-3vm5A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		5 / 12 LEU A 262
THR A 277
TRP A 284
GLY A 259
LEU A 265
 None
 1.41A 5jo9A-3vm5A:
undetectable		 5jo9A-3vm5A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 5 TYR A 450
ILE A 468
GLY A 426
PHE A 427
 None
 0.90A 5kmdC-3vm5A:
undetectable
5kmdD-3vm5A:
undetectable		 5kmdC-3vm5A:
19.92
5kmdD-3vm5A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		3 / 3 VAL A 191
VAL A  93
GLN A  41
 None
 0.61A 5qgjA-3vm5A:
undetectable		 5qgjA-3vm5A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		3 / 3 VAL A 191
VAL A  93
GLN A  41
 None
 0.64A 5qgmA-3vm5A:
undetectable		 5qgmA-3vm5A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		3 / 3 VAL A 191
VAL A  93
GLN A  41
 None
 0.59A 5qgnA-3vm5A:
undetectable		 5qgnA-3vm5A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		3 / 3 VAL A 191
VAL A  93
GLN A  41
 None
 0.61A 5qh5A-3vm5A:
undetectable		 5qh5A-3vm5A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		3 / 3 VAL A 191
VAL A  93
GLN A  41
 None
 0.61A 5qh6A-3vm5A:
undetectable		 5qh6A-3vm5A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		3 / 3 VAL A 191
VAL A  93
GLN A  41
 None
 0.62A 5qh7A-3vm5A:
undetectable		 5qh7A-3vm5A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		3 / 3 VAL A 191
VAL A  93
GLN A  41
 None
 0.65A 5qhaA-3vm5A:
undetectable		 5qhaA-3vm5A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		3 / 3 VAL A 191
VAL A  93
GLN A  41
 None
 0.60A 5qhhA-3vm5A:
undetectable		 5qhhA-3vm5A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 7 LEU A 329
VAL A 384
TYR A 321
SER A 341
 None
 1.32A 5umwA-3vm5A:
undetectable
5umwF-3vm5A:
undetectable		 5umwA-3vm5A:
10.23
5umwF-3vm5A:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		6 / 12 TRP A  58
TYR A  62
GLU A 240
ASP A 197
HIS A 299
ASP A 300
 None
 1.11A 6ag0A-3vm5A:
26.5		 6ag0A-3vm5A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		8 / 12 TRP A  58
TYR A  62
HIS A 101
LEU A 162
ASP A 197
HIS A 201
HIS A 299
ASP A 300
 None
 0.73A 6ag0A-3vm5A:
26.5		 6ag0A-3vm5A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 6 GLY A  90
GLY A  33
PRO A  34
GLY A  36
 None
 0.67A 6ag0C-3vm5A:
26.6		 6ag0C-3vm5A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		5 / 12 TRP A  58
GLU A 240
ASP A 197
HIS A 299
ASP A 300
 None
 1.21A 6ag0C-3vm5A:
26.6		 6ag0C-3vm5A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		6 / 12 TRP A  58
LEU A 162
ASP A 197
HIS A 201
HIS A 299
ASP A 300
 None
 0.65A 6ag0C-3vm5A:
26.6		 6ag0C-3vm5A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		5 / 12 TRP A  58
LEU A 165
ASP A 197
HIS A 299
ASP A 300
 None
 1.47A 6ag0C-3vm5A:
26.6		 6ag0C-3vm5A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 3vm5 ALPHA-AMYLASE
(Oryzias
latipes) 		4 / 5 TYR A 247
GLN A 232
GLY A 238
ILE A 242
 None
 1.46A 6debB-3vm5A:
undetectable		 6debB-3vm5A:
9.89