SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vm7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 7 GLY A 473
THR A 412
HIS A 411
THR A 425
 None
 0.68A 1c9sT-3vm7A:
undetectable
1c9sU-3vm7A:
undetectable		 1c9sT-3vm7A:
8.13
1c9sU-3vm7A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		7 / 12 HIS A 100
TYR A 102
GLU A 249
HIS A 315
ASP A 316
ASP A 359
ARG A 363
 None
None
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
None
None
 1.04A 1dedA-3vm7A:
41.9		 1dedA-3vm7A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		9 / 12 HIS A 100
TYR A 102
LEU A 185
LEU A 192
ASP A 225
HIS A 315
ASP A 316
ASP A 359
ARG A 363
 None
None
None
None
GLC  A 503 (-3.5A)
None
GLC  A 503 (-3.0A)
None
None
 0.71A 1dedA-3vm7A:
41.9		 1dedA-3vm7A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		7 / 12 TYR A 102
LEU A 192
ASP A 225
HIS A 315
ASP A 316
ASP A 359
ARG A 363
 None
None
GLC  A 503 (-3.5A)
None
GLC  A 503 (-3.0A)
None
None
 1.41A 1dedA-3vm7A:
41.9		 1dedA-3vm7A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		9 / 12 HIS A 100
TYR A 102
LEU A 192
ARG A 223
ASP A 225
GLU A 249
HIS A 315
ASP A 316
ARG A 363
 None
None
None
None
GLC  A 503 (-3.5A)
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
None
 0.68A 1dedB-3vm7A:
45.1		 1dedB-3vm7A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 VAL A 247
ILE A  32
ILE A 338
SER A 312
LEU A 269
 None
 1.15A 1fm4A-3vm7A:
undetectable		 1fm4A-3vm7A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 7 GLY A 473
THR A 412
HIS A 411
THR A 425
 None
 0.68A 1gtfL-3vm7A:
undetectable
1gtfM-3vm7A:
undetectable		 1gtfL-3vm7A:
8.13
1gtfM-3vm7A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 8 GLY A 473
THR A 412
HIS A 411
THR A 425
 None
 0.69A 1gtfN-3vm7A:
undetectable
1gtfO-3vm7A:
undetectable		 1gtfN-3vm7A:
8.13
1gtfO-3vm7A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 7 TRP A 367
SER A  46
ASP A  44
PHE A  40
 None
 1.20A 1ismB-3vm7A:
undetectable		 1ismB-3vm7A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		8 / 12 TYR A 102
HIS A 142
ARG A 223
ASP A 225
LYS A 228
GLU A 249
HIS A 315
ASP A 316
 None
None
None
GLC  A 503 (-3.5A)
GLC  A 503 ( 4.4A)
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
 0.40A 1mxdA-3vm7A:
31.7		 1mxdA-3vm7A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 8 GLY A 473
THR A 412
HIS A 411
THR A 425
 None
 0.65A 1utdI-3vm7A:
undetectable
1utdJ-3vm7A:
undetectable		 1utdI-3vm7A:
8.13
1utdJ-3vm7A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 8 VAL A 449
ASP A 482
TYR A 443
LEU A 466
 None
 1.03A 1z2bB-3vm7A:
undetectable		 1z2bB-3vm7A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 7 ASP A 482
THR A 441
GLY A 442
TYR A 443
 None
 0.92A 2f6dA-3vm7A:
undetectable		 2f6dA-3vm7A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		6 / 12 LEU A 185
ARG A 223
ASP A 225
GLU A 249
HIS A 315
ASP A 316
 None
None
GLC  A 503 (-3.5A)
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
 0.73A 3aicA-3vm7A:
5.0		 3aicA-3vm7A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		6 / 12 LEU A 185
ARG A 223
ASP A 225
GLU A 249
HIS A 315
ASP A 316
 None
None
GLC  A 503 (-3.5A)
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
 0.71A 3aicB-3vm7A:
5.2		 3aicB-3vm7A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		6 / 12 ARG A 223
ASP A 225
GLU A 249
HIS A 315
ASP A 316
TYR A 102
 None
GLC  A 503 (-3.5A)
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
None
 0.62A 3aicC-3vm7A:
4.7		 3aicC-3vm7A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		6 / 12 LEU A 185
ARG A 223
ASP A 225
GLU A 249
HIS A 315
ASP A 316
 None
None
GLC  A 503 (-3.5A)
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
 0.79A 3aicD-3vm7A:
5.2		 3aicD-3vm7A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		6 / 12 LEU A 185
ARG A 223
ASP A 225
GLU A 249
HIS A 315
ASP A 316
 None
None
GLC  A 503 (-3.5A)
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
 0.76A 3aicE-3vm7A:
5.1		 3aicE-3vm7A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		6 / 12 LEU A 185
ARG A 223
ASP A 225
GLU A 249
HIS A 315
ASP A 316
 None
None
GLC  A 503 (-3.5A)
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
 0.71A 3aicF-3vm7A:
8.0		 3aicF-3vm7A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		6 / 12 LEU A 185
ARG A 223
ASP A 225
GLU A 249
HIS A 315
ASP A 316
 None
None
GLC  A 503 (-3.5A)
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
 0.73A 3aicG-3vm7A:
4.8		 3aicG-3vm7A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		6 / 12 LEU A 185
ARG A 223
ASP A 225
GLU A 249
HIS A 315
ASP A 316
 None
None
GLC  A 503 (-3.5A)
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
 0.81A 3aicH-3vm7A:
2.6		 3aicH-3vm7A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 VAL A 416
THR A 421
ILE A 387
ALA A 391
ILE A 399
 None
 1.00A 3ddyA-3vm7A:
undetectable		 3ddyA-3vm7A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		3 / 3 ASN A 270
MET A 288
PHE A 336
 None
 0.81A 3g4lD-3vm7A:
undetectable		 3g4lD-3vm7A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 GLY A 442
GLY A 464
GLY A 446
THR A 441
ASP A 404
 None
 0.96A 3gczA-3vm7A:
undetectable		 3gczA-3vm7A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		3 / 3 TYR A 361
GLY A  54
ASP A  52
 None
 0.67A 3ou6C-3vm7A:
undetectable		 3ou6C-3vm7A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 9 ALA A 122
ARG A  64
LEU A 120
ASN A  62
ILE A  86
 None
 1.38A 3wdmA-3vm7A:
undetectable		 3wdmA-3vm7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 9 ALA A 122
ARG A  64
LEU A 120
LEU A  66
ASN A  62
 None
 1.35A 3wdmA-3vm7A:
undetectable		 3wdmA-3vm7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 ILE A 140
PHE A 238
HIS A 229
VAL A 230
ILE A 235
 None
None
GLC  A 503 ( 4.0A)
None
None
 1.04A 4rvdA-3vm7A:
undetectable		 4rvdA-3vm7A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		3 / 3 ASP A 326
LEU A 474
GLY A 473
 None
 0.55A 4xmfA-3vm7A:
undetectable		 4xmfA-3vm7A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 8 ASN A 158
PRO A 159
PHE A 160
SER A 162
 None
None
None
NAG  A 502 ( 4.7A)
 1.26A 5amiB-3vm7A:
undetectable		 5amiB-3vm7A:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 ARG A 223
ASP A 225
GLU A 249
HIS A 315
ASP A 316
 None
GLC  A 503 (-3.5A)
GLC  A 503 (-2.6A)
None
GLC  A 503 (-3.0A)
 0.45A 5csyB-3vm7A:
19.6		 5csyB-3vm7A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 8 GLY A 473
THR A 412
HIS A 411
THR A 425
 None
 0.69A 5eevL-3vm7A:
undetectable
5eevV-3vm7A:
undetectable		 5eevL-3vm7A:
8.13
5eevV-3vm7A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 8 GLY A 473
THR A 412
HIS A 411
THR A 425
 None
 0.70A 5eewL-3vm7A:
undetectable
5eewV-3vm7A:
undetectable		 5eewL-3vm7A:
8.13
5eewV-3vm7A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 8 GLY A 473
THR A 412
HIS A 411
THR A 425
 None
 0.70A 5eezL-3vm7A:
undetectable
5eezV-3vm7A:
undetectable		 5eezL-3vm7A:
8.13
5eezV-3vm7A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 8 GLY A 473
THR A 412
HIS A 411
THR A 425
 None
 0.69A 5ef1L-3vm7A:
undetectable
5ef1V-3vm7A:
undetectable		 5ef1L-3vm7A:
8.13
5ef1V-3vm7A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 8 GLY A 473
THR A 412
HIS A 411
THR A 425
 None
 0.69A 5ef2L-3vm7A:
undetectable
5ef2V-3vm7A:
undetectable		 5ef2L-3vm7A:
8.13
5ef2V-3vm7A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 8 GLY A 473
THR A 412
HIS A 411
THR A 425
 None
 0.69A 5ef3L-3vm7A:
undetectable
5ef3V-3vm7A:
undetectable		 5ef3L-3vm7A:
8.13
5ef3V-3vm7A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 GLY A 442
GLY A 464
GLY A 446
THR A 441
ASP A 404
 None
 0.96A 5ehiA-3vm7A:
undetectable		 5ehiA-3vm7A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 GLY A 442
GLY A 464
GLY A 446
THR A 441
ASP A 404
 None
 0.94A 5ehiC-3vm7A:
undetectable		 5ehiC-3vm7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 GLY A 442
GLY A 464
GLY A 446
THR A 441
ASP A 404
 None
 0.97A 5eiwA-3vm7A:
undetectable		 5eiwA-3vm7A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 GLY A 442
GLY A 464
GLY A 446
THR A 441
ASP A 404
 None
 0.99A 5ekxA-3vm7A:
undetectable		 5ekxA-3vm7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 PRO A 305
GLY A 342
ARG A 306
ILE A 399
ILE A 345
 None
 1.13A 5fa8A-3vm7A:
undetectable		 5fa8A-3vm7A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 11 ASN A 394
VAL A 449
ASP A 482
TYR A 443
LEU A 466
 None
 1.22A 5jh7B-3vm7A:
undetectable		 5jh7B-3vm7A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 11 ASN A 394
VAL A 449
ASP A 482
TYR A 443
LEU A 466
 None
 1.25A 5jh7D-3vm7A:
undetectable		 5jh7D-3vm7A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		3 / 3 TYR A  72
TYR A 354
GLN A 352
 None
 1.00A 5jsdA-3vm7A:
undetectable
5jsdB-3vm7A:
undetectable		 5jsdA-3vm7A:
20.27
5jsdB-3vm7A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		3 / 3 TYR A  72
TYR A 354
GLN A 352
 None
 0.98A 5jsdB-3vm7A:
undetectable
5jsdC-3vm7A:
undetectable		 5jsdB-3vm7A:
20.27
5jsdC-3vm7A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 THR A 425
THR A 412
SER A 283
GLY A 286
ALA A 280
 None
 1.34A 5lf3b-3vm7A:
undetectable		 5lf3b-3vm7A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 THR A 425
THR A 412
SER A 283
GLY A 286
ALA A 280
 None
 1.36A 5lf3N-3vm7A:
undetectable		 5lf3N-3vm7A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		3 / 3 ASP A 293
ASN A 294
ASP A 254
 None
 0.82A 5vopA-3vm7A:
3.1		 5vopA-3vm7A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		5 / 12 GLY A 442
GLY A 464
GLY A 446
THR A 441
ASP A 404
 None
 0.91A 5wz1B-3vm7A:
undetectable		 5wz1B-3vm7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		3 / 3 VAL A 202
TYR A 165
GLU A 198
 None
 0.89A 5zmqD-3vm7A:
1.5
5zmqE-3vm7A:
undetectable		 5zmqD-3vm7A:
16.50
5zmqE-3vm7A:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		8 / 12 TYR A 102
HIS A 142
LEU A 185
ASP A 225
LYS A 228
HIS A 229
HIS A 315
ASP A 316
 None
None
None
GLC  A 503 (-3.5A)
GLC  A 503 ( 4.4A)
GLC  A 503 ( 4.0A)
None
GLC  A 503 (-3.0A)
 0.62A 6ag0A-3vm7A:
27.4		 6ag0A-3vm7A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		7 / 12 LEU A 185
ASP A 225
LYS A 228
HIS A 229
TYR A 275
HIS A 315
ASP A 316
 None
GLC  A 503 (-3.5A)
GLC  A 503 ( 4.4A)
GLC  A 503 ( 4.0A)
None
None
GLC  A 503 (-3.0A)
 0.90A 6ag0C-3vm7A:
27.4		 6ag0C-3vm7A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 5 THR A  87
LEU A 195
VAL A 230
LEU A 185
 None
 0.97A 6bqgA-3vm7A:
undetectable		 6bqgA-3vm7A:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 3vm7 ALPHA-AMYLASE
(Malbranchea
cinnamomea) 		4 / 4 HIS A 380
VAL A 477
LEU A 453
ALA A 335
 None
 1.15A 6d8pB-3vm7A:
undetectable		 6d8pB-3vm7A:
22.80