SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vm8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3vm8 PROBABLE DNA
DC->DU-EDITING
ENZYME APOBEC-3C
(Homo
sapiens) 		5 / 10 ALA A 101
LEU A  72
PHE A  71
LEU A  35
ALA A  67
 None
 1.18A 1g5yC-3vm8A:
undetectable		 1g5yC-3vm8A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 3vm8 PROBABLE DNA
DC->DU-EDITING
ENZYME APOBEC-3C
(Homo
sapiens) 		5 / 12 ILE A 118
THR A  38
THR A 117
VAL A 145
PRO A  96
 None
 1.31A 2yzqA-3vm8A:
undetectable		 2yzqA-3vm8A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3vm8 PROBABLE DNA
DC->DU-EDITING
ENZYME APOBEC-3C
(Homo
sapiens) 		4 / 6 PRO A  14
GLY A  15
THR A  16
LYS A  22
 None
 1.10A 5xxiA-3vm8A:
undetectable		 5xxiA-3vm8A:
19.20