SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vmn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 7 ARG A 217
ASP A 211
ASP A 210
ARG A 591
 None
 1.49A 1ceaB-3vmnA:
undetectable		 1ceaB-3vmnA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		5 / 9 VAL A 392
GLY A 388
ILE A 387
VAL A 341
ILE A 327
 None
 1.16A 1hpvB-3vmnA:
undetectable		 1hpvB-3vmnA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_A_DAHA382_1
(AMINE OXIDASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		6 / 10 THR A 645
ASP A 647
TYR A 470
VAL A 524
HIS A 538
MET A 494
 None
 1.37A 1ivvA-3vmnA:
undetectable		 1ivvA-3vmnA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_B_DAHB382_1
(AMINE OXIDASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		6 / 10 THR A 645
ASP A 647
TYR A 470
VAL A 524
HIS A 538
MET A 494
 None
 1.36A 1ivvB-3vmnA:
undetectable		 1ivvB-3vmnA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 6 TYR A 257
ASN A 432
TYR A 307
TYR A 561
 None
 1.49A 1kiaA-3vmnA:
3.0		 1kiaA-3vmnA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 6 TYR A 257
ASN A 432
TYR A 307
TYR A 561
 None
 1.49A 1kiaB-3vmnA:
0.0		 1kiaB-3vmnA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 7 TYR A 257
ASN A 432
TYR A 307
TYR A 561
 None
 1.49A 1kiaC-3vmnA:
undetectable		 1kiaC-3vmnA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 7 TYR A 257
ASN A 432
TYR A 307
TYR A 561
 None
 1.48A 1kiaD-3vmnA:
undetectable		 1kiaD-3vmnA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 7 TYR A 257
ASN A 432
TYR A 307
TYR A 561
 None
 1.50A 1nbhB-3vmnA:
1.2		 1nbhB-3vmnA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 6 TYR A 257
ASN A 432
TYR A 307
TYR A 561
 None
 1.50A 1nbhC-3vmnA:
1.3		 1nbhC-3vmnA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 6 LEU A 726
TRP A 624
TYR A 470
TYR A 579
 None
 1.48A 1qvuA-3vmnA:
undetectable		 1qvuA-3vmnA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		3 / 3 PRO A 671
THR A 673
PRO A 715
 None
 0.81A 2d55C-3vmnA:
undetectable		 2d55C-3vmnA:
1.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 8 ILE A 531
GLN A 580
LEU A 541
GLY A 491
 None
 0.84A 2qqcH-3vmnA:
undetectable
2qqcK-3vmnA:
undetectable		 2qqcH-3vmnA:
10.08
2qqcK-3vmnA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 5 LEU A 638
GLN A 602
THR A 603
THR A 635
 None
 0.85A 2zj0B-3vmnA:
undetectable		 2zj0B-3vmnA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 5 LEU A 638
GLN A 602
THR A 603
THR A 635
 None
 1.03A 2zj0C-3vmnA:
2.5		 2zj0C-3vmnA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 4 LEU A 638
GLN A 602
THR A 603
THR A 635
 None
 0.99A 2zj0D-3vmnA:
2.1		 2zj0D-3vmnA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 8 ILE A 489
TRP A 212
TYR A 537
ARG A 591
 None
 1.16A 3ccfB-3vmnA:
undetectable		 3ccfB-3vmnA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 5 LEU A 638
GLN A 602
THR A 603
THR A 635
 None
 1.01A 3ce6B-3vmnA:
undetectable		 3ce6B-3vmnA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		3 / 3 SER A 283
ASP A 274
ASP A 258
 None
 0.88A 3iv6A-3vmnA:
undetectable		 3iv6A-3vmnA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		3 / 3 SER A 283
ASP A 274
ASP A 258
 None
 0.87A 3iv6C-3vmnA:
undetectable		 3iv6C-3vmnA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 7 ILE A 583
LEU A 541
THR A 521
ARG A 574
 None
 0.91A 3nxuA-3vmnA:
undetectable		 3nxuA-3vmnA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 8 ASP A 597
TYR A 626
PRO A 601
GLN A 602
 None
 1.08A 3oyaA-3vmnA:
2.6		 3oyaA-3vmnA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 7 ASP A 597
TYR A 626
PRO A 601
GLN A 602
 None
 1.13A 3s3oA-3vmnA:
2.5		 3s3oA-3vmnA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 7 PRO A 497
GLY A 508
ALA A 510
ALA A 515
 None
 0.85A 3ur0B-3vmnA:
undetectable		 3ur0B-3vmnA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 5 ASP A 512
THR A 518
LEU A 566
GLU A 495
 None
 1.12A 4a3pA-3vmnA:
undetectable		 4a3pA-3vmnA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 6 PHE A 256
ALA A 302
THR A 300
LEU A 243
 None
 1.00A 4ejgD-3vmnA:
undetectable		 4ejgD-3vmnA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 7 TYR A 493
TYR A 561
LEU A 556
TYR A 537
 None
 1.20A 4f8yC-3vmnA:
undetectable
4f8yD-3vmnA:
undetectable		 4f8yC-3vmnA:
16.49
4f8yD-3vmnA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 6 ILE A 450
THR A 484
VAL A 434
SER A 445
 None
 1.14A 4iaqA-3vmnA:
undetectable		 4iaqA-3vmnA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 5 TYR A 560
GLY A 222
GLU A 557
VAL A 524
 None
 1.16A 4nkvD-3vmnA:
undetectable		 4nkvD-3vmnA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		3 / 3 TYR A 731
THR A 690
THR A 635
 None
 0.69A 5aoxB-3vmnA:
0.1		 5aoxB-3vmnA:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		3 / 3 TYR A 731
THR A 690
THR A 635
 None
 0.69A 5aoxE-3vmnA:
0.1		 5aoxE-3vmnA:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 6 THR A 138
ALA A 139
THR A 140
VAL A 189
 None
 0.98A 5ecoA-3vmnA:
undetectable		 5ecoA-3vmnA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA407_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 5 THR A 459
GLN A 467
ARG A 476
GLU A 437
 None
 1.37A 5k9dA-3vmnA:
3.8		 5k9dA-3vmnA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		5 / 12 LEU A 639
ALA A 529
PRO A 692
LEU A 696
LEU A 689
 None
 1.06A 5ljeA-3vmnA:
undetectable		 5ljeA-3vmnA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		3 / 3 VAL A 524
TYR A 519
GLN A 520
 None
 0.66A 5qgkA-3vmnA:
undetectable		 5qgkA-3vmnA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		3 / 3 VAL A 524
TYR A 519
GLN A 520
 None
 0.68A 5qgrA-3vmnA:
undetectable		 5qgrA-3vmnA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		3 / 3 VAL A 524
TYR A 519
GLN A 520
 None
 0.71A 5qgtA-3vmnA:
undetectable		 5qgtA-3vmnA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 7 ILE A 583
LEU A 541
THR A 521
ARG A 574
 None
 0.93A 5vc0A-3vmnA:
undetectable		 5vc0A-3vmnA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		5 / 12 LEU A 672
ILE A 732
LEU A 638
VAL A 668
LEU A 590
 None
 1.01A 5ycnA-3vmnA:
undetectable		 5ycnA-3vmnA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 5 ASN A 248
TYR A 115
VAL A 208
LEU A 179
 None
 1.22A 6a7pA-3vmnA:
undetectable		 6a7pA-3vmnA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3vmn DEXTRANASE
(Streptococcus
mutans) 		4 / 6 TRP A 648
GLY A 535
ALA A 530
LEU A 473
 None
 1.04A 6fosA-3vmnA:
undetectable		 6fosA-3vmnA:
8.43