SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vnf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3vnf MEMBRANE-ASSOCIATED
PROTEIN VP24
(Sudan
ebolavirus) 		5 / 10 GLY A 117
LEU A 121
LEU A 119
ILE A 122
LEU A 145
 None
 1.04A 2f8dA-3vnfA:
undetectable		 2f8dA-3vnfA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3vnf MEMBRANE-ASSOCIATED
PROTEIN VP24
(Sudan
ebolavirus) 		5 / 10 GLY A 117
LEU A 121
LEU A 119
ILE A 122
LEU A 145
 None
 1.07A 2f8dB-3vnfA:
undetectable		 2f8dB-3vnfA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3vnf MEMBRANE-ASSOCIATED
PROTEIN VP24
(Sudan
ebolavirus) 		4 / 5 VAL A 170
VAL A 169
THR A 191
ARG A 192
 None
 1.17A 3bjwA-3vnfA:
undetectable		 3bjwA-3vnfA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 3vnf MEMBRANE-ASSOCIATED
PROTEIN VP24
(Sudan
ebolavirus) 		4 / 7 LEU A  94
ILE A 188
ILE A 190
VAL A 199
 None
 0.83A 4ojbA-3vnfA:
undetectable		 4ojbA-3vnfA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vnf MEMBRANE-ASSOCIATED
PROTEIN VP24
(Sudan
ebolavirus) 		3 / 3 CYH A  27
MET A 136
ASN A 135
 None
 1.32A 5qh8A-3vnfA:
undetectable		 5qh8A-3vnfA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3vnf MEMBRANE-ASSOCIATED
PROTEIN VP24
(Sudan
ebolavirus) 		5 / 10 TYR A 197
ILE A 102
ILE A 122
LEU A 121
ILE A 181
 None
 1.46A 5vkqA-3vnfA:
undetectable
5vkqD-3vnfA:
undetectable		 5vkqA-3vnfA:
8.61
5vkqD-3vnfA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3vnf MEMBRANE-ASSOCIATED
PROTEIN VP24
(Sudan
ebolavirus) 		3 / 3 LYS A  52
ASN A  50
SER A 225
 None
 1.17A 5yw0A-3vnfA:
undetectable		 5yw0A-3vnfA:
22.67