SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vnw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 3vnw CYTOCHROME C-552
(Thermus
thermophilus) 		5 / 12 GLY A  19
GLY A  21
ILE A  87
ALA A  90
ASP A  93
 None
None
HEM  A 200 ( 4.7A)
None
None
 1.11A 4kicA-3vnwA:
undetectable		 4kicA-3vnwA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 3vnw CYTOCHROME C-552
(Thermus
thermophilus) 		5 / 12 GLY A  19
GLY A  21
ILE A  87
ALA A  90
ASP A  93
 None
None
HEM  A 200 ( 4.7A)
None
None
 1.13A 4kicB-3vnwA:
undetectable		 4kicB-3vnwA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_ACTA605_0
(SERUM ALBUMIN)		 3vnw CYTOCHROME C-552
(Thermus
thermophilus) 		3 / 3 LYS A  96
LYS A  61
ALA A  30
 None
 1.16A 4ot2A-3vnwA:
0.5		 4ot2A-3vnwA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 3vnw CYTOCHROME C-552
(Thermus
thermophilus) 		4 / 5 HIS A  32
GLU A  35
VAL A  60
LYS A  61
 HEM  A 200 (-3.7A)
None
HEM  A 200 (-4.9A)
None
 1.36A 4p6vB-3vnwA:
undetectable
4p6vE-3vnwA:
undetectable		 4p6vB-3vnwA:
14.01
4p6vE-3vnwA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 3vnw CYTOCHROME C-552
(Thermus
thermophilus) 		4 / 5 HIS A  32
VAL A  33
GLU A  35
VAL A  60
 HEM  A 200 (-3.7A)
None
None
HEM  A 200 (-4.9A)
 1.43A 4p6vB-3vnwA:
undetectable
4p6vE-3vnwA:
undetectable		 4p6vB-3vnwA:
14.01
4p6vE-3vnwA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3vnw CYTOCHROME C-552
(Thermus
thermophilus) 		4 / 7 ALA A  90
THR A  89
VAL A  33
HIS A  86
 None
 0.99A 5ecnA-3vnwA:
undetectable		 5ecnA-3vnwA:
12.43