SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vo2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
5 / 12 LEU A 200
GLY A 173
CYH A 114
ALA A 175
ALA A  98
None
None
None
FAD  A 401 ( 4.0A)
None
1.09A 2br4A-3vo2A:
3.6
2br4A-3vo2A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
5 / 12 LEU A 200
GLY A 173
CYH A 114
ALA A 175
ALA A  98
None
None
None
FAD  A 401 ( 4.0A)
None
1.18A 2br4D-3vo2A:
2.5
2br4D-3vo2A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
5 / 12 ILE A 174
LEU A 200
GLY A 203
SER A 234
GLN A 237
None
1.21A 2ogyB-3vo2A:
undetectable
2ogyB-3vo2A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
5 / 9 LEU A 211
ILE A 174
GLY A 173
GLY A 273
SER A 209
None
1.09A 2qmmA-3vo2A:
undetectable
2qmmA-3vo2A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
5 / 12 ILE A 174
LEU A 200
GLY A 203
SER A 234
GLN A 237
None
1.19A 2ycjA-3vo2A:
undetectable
2ycjA-3vo2A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
5 / 12 GLY A  40
ILE A 147
TYR A  70
ALA A  98
SER A 112
None
1.00A 3hs6B-3vo2A:
undetectable
3hs6B-3vo2A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
3 / 3 PRO A 161
SER A 195
ASN A 266
None
0.77A 3lslG-3vo2A:
undetectable
3lslG-3vo2A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
5 / 9 ILE A 166
LEU A 168
ILE A 281
MET A 297
ILE A 284
None
1.15A 3zosA-3vo2A:
undetectable
3zosA-3vo2A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
5 / 9 ILE A 166
LEU A 168
ILE A 281
MET A 297
ILE A 284
None
1.15A 3zosB-3vo2A:
undetectable
3zosB-3vo2A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
5 / 10 ILE A 247
ILE A 174
GLY A 173
GLY A 273
PHE A 231
None
0.85A 4fakA-3vo2A:
undetectable
4fakA-3vo2A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
4 / 7 PHE A 105
ASP A 104
SER A 112
SER A  44
None
1.21A 4lv9A-3vo2A:
undetectable
4lv9B-3vo2A:
undetectable
4lv9A-3vo2A:
19.68
4lv9B-3vo2A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
4 / 5 LEU A 200
LEU A 229
MET A 184
TYR A 270
None
1.32A 5uc3A-3vo2A:
undetectable
5uc3A-3vo2A:
13.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
7 / 9 SER A  96
THR A 172
GLY A 173
ALA A 175
CYH A 272
GLY A 273
GLU A 312
FAD  A 401 (-3.2A)
FAD  A 401 (-3.3A)
None
FAD  A 401 ( 4.0A)
None
None
FAD  A 401 (-3.8A)
0.43A 5vw4A-3vo2A:
41.5
5vw4A-3vo2A:
49.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
6 / 8 SER A  96
THR A 172
GLY A 173
CYH A 272
GLY A 273
GLU A 312
FAD  A 401 (-3.2A)
FAD  A 401 (-3.3A)
None
None
None
FAD  A 401 (-3.8A)
0.47A 5vw5A-3vo2A:
41.3
5vw5A-3vo2A:
49.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW9_A_ACTA404_0
(FERREDOXIN--NADP
REDUCTASE)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
4 / 4 THR A 170
TYR A 246
LEU A 274
MET A 277
None
0.78A 5vw9A-3vo2A:
41.7
5vw9A-3vo2A:
49.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)
3vo2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Zea
mays)
4 / 6 ILE A  97
TYR A  70
ARG A 178
SER A 179
None
1.23A 6f6jA-3vo2A:
undetectable
6f6jA-3vo2A:
undetectable