SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3voh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 ALA A 140
LYS A 197
ARG A 196
ILE A 203
THR A 141
 None
 1.30A 1d1gA-3vohA:
undetectable		 1d1gA-3vohA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 4 ILE A 285
LEU A 212
VAL A 235
ILE A 207
 None
 0.94A 1fm6D-3vohA:
undetectable		 1fm6D-3vohA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 ILE A 336
LEU A 368
PHE A  81
ILE A  86
LEU A 152
 None
 1.20A 1jolA-3vohA:
undetectable		 1jolA-3vohA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 7 LEU A 239
LEU A 212
LEU A 288
GLY A 287
 None
 0.89A 1n13D-3vohA:
undetectable
1n13E-3vohA:
undetectable		 1n13D-3vohA:
15.72
1n13E-3vohA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 8 ASP A 132
TYR A 187
LEU A 191
GLY A 134
 None
 0.90A 1rmtC-3vohA:
undetectable		 1rmtC-3vohA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QK8_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 ALA A 429
VAL A 115
LYS A 116
ILE A 103
PHE A 422
 None
 0.95A 2qk8A-3vohA:
undetectable		 2qk8A-3vohA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 THR A 290
GLY A 254
GLY A 287
ASN A 291
LEU A 259
 None
 1.10A 3eeyA-3vohA:
undetectable		 3eeyA-3vohA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 THR A 290
GLY A 254
GLY A 287
ASN A 291
LEU A 259
 None
 1.13A 3eeyB-3vohA:
undetectable		 3eeyB-3vohA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 THR A 290
GLY A 254
GLY A 287
ASN A 291
LEU A 259
 None
 1.11A 3eeyC-3vohA:
undetectable		 3eeyC-3vohA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 THR A 290
GLY A 254
GLY A 287
ASN A 291
LEU A 259
 None
 1.11A 3eeyD-3vohA:
undetectable		 3eeyD-3vohA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 THR A 290
GLY A 254
GLY A 287
ASN A 291
LEU A 259
 None
 1.14A 3eeyH-3vohA:
undetectable		 3eeyH-3vohA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 THR A 290
GLY A 254
GLY A 287
ASN A 291
LEU A 259
 None
 1.14A 3eeyI-3vohA:
undetectable		 3eeyI-3vohA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 THR A 290
GLY A 254
GLY A 287
ASN A 291
LEU A 259
 None
 1.17A 3eeyJ-3vohA:
undetectable		 3eeyJ-3vohA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		3 / 3 ARG A 190
ASP A 159
ASP A 186
 None
 0.91A 3jb2A-3vohA:
undetectable		 3jb2A-3vohA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		3 / 3 ARG A 190
ASP A 159
ASP A 186
 None
 0.79A 3jb3A-3vohA:
1.4		 3jb3A-3vohA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 ASP A 200
SER A 249
THR A 141
ALA A 238
ALA A 244
 None
 1.35A 3ua1A-3vohA:
undetectable		 3ua1A-3vohA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 7 PHE A 422
PHE A 362
ALA A 429
LEU A 108
 None
 1.01A 4ejgA-3vohA:
undetectable		 4ejgA-3vohA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 8 PHE A 422
VAL A  96
LEU A 433
TYR A  92
 None
 1.13A 4f5zA-3vohA:
undetectable		 4f5zA-3vohA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 7 GLY A 384
GLY A 385
TYR A 421
ASN A 356
 None
 1.00A 4fgkB-3vohA:
undetectable		 4fgkB-3vohA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 LEU A 322
GLY A 254
ASN A 294
ALA A 213
ASN A 214
 None
None
CT3  A1002 (-3.9A)
None
CT3  A1002 ( 4.9A)
 1.37A 4pclB-3vohA:
undetectable		 4pclB-3vohA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 6 ASP A 314
ALA A 256
THR A 307
TYR A 313
 None
 1.29A 4w5qA-3vohA:
undetectable		 4w5qA-3vohA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 6 ASP A 314
ALA A 256
THR A 307
TYR A 313
 None
 1.23A 4w5rA-3vohA:
undetectable		 4w5rA-3vohA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 6 ASP A 314
ALA A 256
THR A 307
TYR A 313
 None
 1.24A 4w5tA-3vohA:
undetectable		 4w5tA-3vohA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 6 TYR A 198
LYS A 197
LEU A 133
GLU A 194
 None
 1.32A 4z4cA-3vohA:
undetectable		 4z4cA-3vohA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 6 ASP A 314
ALA A 256
THR A 307
TYR A 313
 None
 1.24A 4z4cA-3vohA:
undetectable		 4z4cA-3vohA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 6 ASP A 314
ALA A 256
THR A 307
TYR A 313
 None
 1.28A 4z4fA-3vohA:
undetectable		 4z4fA-3vohA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 5 ASP A 314
ALA A 256
THR A 307
TYR A 313
 None
 1.25A 4z4gA-3vohA:
undetectable		 4z4gA-3vohA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 5 TYR A 198
LYS A 197
LEU A 133
GLU A 194
 None
 1.30A 4z4hA-3vohA:
undetectable		 4z4hA-3vohA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 5 ASP A 314
ALA A 256
THR A 307
TYR A 313
 None
 1.25A 4z4hA-3vohA:
0.9		 4z4hA-3vohA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 6 ASP A 314
ALA A 256
THR A 307
TYR A 313
 None
 1.26A 4z4iA-3vohA:
undetectable		 4z4iA-3vohA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 7 ILE A 347
VAL A 357
TYR A 421
ARG A 341
 None
 1.19A 5kkzC-3vohA:
undetectable
5kkzE-3vohA:
undetectable		 5kkzC-3vohA:
21.33
5kkzE-3vohA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 7 ILE A 347
VAL A 357
TYR A 421
ARG A 341
 None
 1.15A 5kkzM-3vohA:
undetectable
5kkzO-3vohA:
undetectable		 5kkzM-3vohA:
21.33
5kkzO-3vohA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		3 / 3 LEU A 325
LEU A 326
TRP A 331
 None
 0.91A 5nwuA-3vohA:
undetectable		 5nwuA-3vohA:
6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 5 TYR A 198
LYS A 197
LEU A 133
GLU A 194
 None
 1.26A 5weaA-3vohA:
undetectable		 5weaA-3vohA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 ILE A 285
GLY A 287
LEU A 212
VAL A 235
ILE A 207
 None
 1.00A 5ycnA-3vohA:
undetectable		 5ycnA-3vohA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 7 ALA A 140
THR A 141
ILE A 155
VAL A 153
 None
 0.88A 6cduF-3vohA:
undetectable
6cduJ-3vohA:
undetectable		 6cduF-3vohA:
22.22
6cduJ-3vohA:
22.22