SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vol'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3vol AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 230
LEU A 244
ASN A 194
ILE A 196
 HEM  A 401 (-3.8A)
HEM  A 401 ( 4.9A)
None
None
 0.71A 1yc2E-3volA:
undetectable		 1yc2E-3volA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3vol AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 231
ASN A 229
ASP A 192
 None
 0.83A 5vopA-3volA:
undetectable		 5vopA-3volA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3vol AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 231
ASN A 229
ASP A 192
 None
 0.84A 5vopB-3volA:
undetectable		 5vopB-3volA:
24.36