SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vom'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 146
ASP A 145
HIS A 102
ARG A 229
GLY A 123
 None
 1.33A 1ia0B-3vomA:
undetectable		 1ia0B-3vomA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 146
ASP A 145
HIS A 102
ARG A 229
GLY A 123
 None
 1.33A 1tubB-3vomA:
undetectable		 1tubB-3vomA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 182
VAL A 186
LEU A  68
LEU A 274
LEU A 210
 None
 0.80A 1ya4C-3vomA:
undetectable		 1ya4C-3vomA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 PRO A 198
GLY A  82
ASN A  81
GLY A  80
 None
 0.91A 1zlqA-3vomA:
undetectable		 1zlqA-3vomA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 SER A 309
VAL A 158
SER A 179
VAL A 311
 None
None
PLP  A 401 ( 3.9A)
None
 1.35A 2j9cA-3vomA:
undetectable
2j9cB-3vomA:
undetectable
2j9cC-3vomA:
undetectable		 2j9cA-3vomA:
15.31
2j9cB-3vomA:
15.31
2j9cC-3vomA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 THR A  85
ALA A  86
LEU A 235
LEU A 237
ILE A  96
 PLP  A 401 (-3.6A)
None
None
None
None
 1.12A 2qxsA-3vomA:
undetectable		 2qxsA-3vomA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 9 ILE A  96
PHE A 112
ALA A 113
VAL A 116
 None
 0.61A 2vufA-3vomA:
undetectable		 2vufA-3vomA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 10 VAL A 146
ASP A 145
PHE A  87
ARG A 220
LEU A 237
 None
 1.34A 3j6gB-3vomA:
undetectable		 3j6gB-3vomA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_D_TA1D502_1
(TUBULIN BETA CHAIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 10 VAL A 146
ASP A 145
PHE A  87
ARG A 220
LEU A 237
 None
 1.34A 3j6gD-3vomA:
undetectable		 3j6gD-3vomA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_F_TA1F502_1
(TUBULIN BETA CHAIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 10 VAL A 146
ASP A 145
PHE A  87
ARG A 220
LEU A 237
 None
 1.34A 3j6gF-3vomA:
undetectable		 3j6gF-3vomA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_H_TA1H502_1
(TUBULIN BETA CHAIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 10 VAL A 146
ASP A 145
PHE A  87
ARG A 220
LEU A 237
 None
 1.34A 3j6gH-3vomA:
undetectable		 3j6gH-3vomA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_J_TA1J502_1
(TUBULIN BETA CHAIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 10 VAL A 146
ASP A 145
PHE A  87
ARG A 220
LEU A 237
 None
 1.34A 3j6gJ-3vomA:
undetectable		 3j6gJ-3vomA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_L_TA1L502_1
(TUBULIN BETA CHAIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 10 VAL A 146
ASP A 145
PHE A  87
ARG A 220
LEU A 237
 None
 1.34A 3j6gL-3vomA:
undetectable		 3j6gL-3vomA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_N_TA1N502_1
(TUBULIN BETA CHAIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 10 VAL A 146
ASP A 145
PHE A  87
ARG A 220
LEU A 237
 None
 1.34A 3j6gN-3vomA:
2.0		 3j6gN-3vomA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_P_TA1P502_1
(TUBULIN BETA CHAIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 10 VAL A 146
ASP A 145
PHE A  87
ARG A 220
LEU A 237
 None
 1.34A 3j6gP-3vomA:
undetectable		 3j6gP-3vomA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_R_TA1R502_1
(TUBULIN BETA CHAIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 10 VAL A 146
ASP A 145
PHE A  87
ARG A 220
LEU A 237
 None
 1.34A 3j6gR-3vomA:
2.0		 3j6gR-3vomA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 11 ILE A 315
SER A 285
LEU A 288
THR A 299
ALA A 292
 None
 1.17A 3kw2A-3vomA:
undetectable		 3kw2A-3vomA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 11 ILE A 315
SER A 285
LEU A 288
THR A 299
ALA A 292
 None
 1.18A 3kw2B-3vomA:
undetectable		 3kw2B-3vomA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 11 LEU A  71
ILE A 221
ILE A  78
LEU A  79
VAL A  58
 None
 1.13A 3w67A-3vomA:
undetectable		 3w67A-3vomA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 GLY A  80
ILE A  78
VAL A  58
SER A 244
 None
 1.11A 4d33A-3vomA:
undetectable		 4d33A-3vomA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 GLY A  80
ILE A  78
VAL A  58
SER A 244
 None
 1.13A 4d33B-3vomA:
undetectable		 4d33B-3vomA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  59
ARG A  60
ALA A 262
GLY A  64
ALA A 352
 None
 1.05A 4l6v1-3vomA:
undetectable
4l6v6-3vomA:
undetectable		 4l6v1-3vomA:
21.04
4l6v6-3vomA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 7 SER A 109
ARG A 350
SER A 155
GLU A 153
 None
 1.37A 4xzkA-3vomA:
undetectable		 4xzkA-3vomA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 162
LEU A 274
LEU A  68
ILE A 188
ILE A 212
 None
 0.89A 4y0rA-3vomA:
undetectable		 4y0rA-3vomA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 8 PHE A 112
SER A 109
TRP A 149
TYR A 105
 None
 1.38A 5amiB-3vomA:
undetectable		 5amiB-3vomA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  80
GLY A  82
ALA A 211
ILE A  78
LEU A  79
 None
 1.17A 5bw4B-3vomA:
undetectable		 5bw4B-3vomA:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 316
ARG A 346
LEU A 344
SER A 179
LYS A 200
 None
None
None
PLP  A 401 ( 3.9A)
PLP  A 401 (-2.6A)
 1.09A 5il1A-3vomA:
undetectable		 5il1A-3vomA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 PHE A  87
GLY A  80
SER A 244
VAL A  61
ALA A 197
 None
None
None
None
PLP  A 401 (-3.4A)
 1.09A 5kpcB-3vomA:
undetectable		 5kpcB-3vomA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 PHE A  22
ALA A 292
THR A 298
ALA A 323
GLU A 339
 None
 1.12A 5vceA-3vomA:
undetectable		 5vceA-3vomA:
22.07