SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3voq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA502_0 (CHORISMATE SYNTHASE)	3voq	TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 (Homo sapiens)	3 / 3	GLY A 406 ASP A 407 SER A 434	None	0.74A	2qhfA-3voqA: undetectable	2qhfA-3voqA: 14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R2V_D_ACTD36_0 (GCN4 LEUCINE ZIPPER)	3voq	TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 (Homo sapiens)	3 / 3	SER A 405 TYR A 383 HIS A 382	None	0.63A	2r2vD-3voqA: undetectable	2r2vD-3voqA: 15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RUK_A_AERA601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	3voq	TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 (Homo sapiens)	5 / 12	PHE A 453 ILE A 411 LEU A 402 THR A 397 VAL A 388	None	0.95A	3rukA-3voqA: undetectable	3rukA-3voqA: 15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RUK_B_AERB601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	3voq	TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 (Homo sapiens)	5 / 12	PHE A 453 ILE A 411 LEU A 402 THR A 397 VAL A 388	None	0.97A	3rukB-3voqA: undetectable	3rukB-3voqA: 15.07

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QHF_A_ACTA502_0","CHORISMATE SYNTHASE","3voq","TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1","Homo sapiens",3,"GLY A 406;ASP A 407;SER A 434","None","0.74A","2qhfA-3voqA:undetectable","2qhfA-3voqA:14.37"],["2R2V_D_ACTD36_0","GCN4 LEUCINE ZIPPER","3voq","TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1","Homo sapiens",3,"SER A 405;TYR A 383;HIS A 382","None","0.63A","2r2vD-3voqA:undetectable","2r2vD-3voqA:15.97"],["3RUK_A_AERA601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","3voq","TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1","Homo sapiens",5,"PHE A 453;ILE A 411;LEU A 402;THR A 397;VAL A 388","None","0.95A","3rukA-3voqA:undetectable","3rukA-3voqA:15.07"],["3RUK_B_AERB601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","3voq","TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1","Homo sapiens",5,"PHE A 453;ILE A 411;LEU A 402;THR A 397;VAL A 388","None","0.97A","3rukB-3voqA:undetectable","3rukB-3voqA:15.07"]]