SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		4 / 8 ALA A 185
LEU A 180
LEU A 260
LEU A 259
 None
 0.98A 1dvtA-3vovA:
undetectable
1dvtB-3vovA:
undetectable		 1dvtA-3vovA:
17.54
1dvtB-3vovA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 GLY A 175
GLY A 166
GLY A 165
GLU A 174
LEU A 173
 None
None
None
None
ZN  A 401 ( 4.9A)
 1.18A 1qzzA-3vovA:
undetectable		 1qzzA-3vovA:
25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_C_T44C601_1
(TRANSTHYRETIN)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 9 LYS A  26
LEU A  23
ALA A  50
LEU A   6
ALA A 290
 None
 1.44A 1sn0A-3vovA:
undetectable
1sn0C-3vovA:
undetectable		 1sn0A-3vovA:
18.64
1sn0C-3vovA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 ILE A  76
ASP A 107
THR A  31
ILE A  13
LEU A  43
 None
 1.17A 1tdrA-3vovA:
undetectable		 1tdrA-3vovA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 GLY A 175
GLY A 166
GLY A 165
GLU A 174
LEU A 173
 None
None
None
None
ZN  A 401 ( 4.9A)
 1.18A 1xdsA-3vovA:
undetectable		 1xdsA-3vovA:
25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 GLY A 175
GLY A 166
GLY A 165
GLU A 174
LEU A 173
 None
None
None
None
ZN  A 401 ( 4.9A)
 1.16A 1xdsB-3vovA:
undetectable		 1xdsB-3vovA:
25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 GLY A 144
LEU A 295
GLY A 288
ALA A 110
ALA A 108
 None
 1.01A 2bm9F-3vovA:
undetectable		 2bm9F-3vovA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		3 / 3 CYH A 171
CYH A 176
HIS A 159
 ZN  A 401 (-2.3A)
ZN  A 401 (-2.3A)
ZN  A 401 (-3.1A)
 0.79A 2iwkA-3vovA:
undetectable		 2iwkA-3vovA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		3 / 3 CYH A 171
CYH A 176
HIS A 159
 ZN  A 401 (-2.3A)
ZN  A 401 (-2.3A)
ZN  A 401 (-3.1A)
 0.79A 2iwkB-3vovA:
undetectable		 2iwkB-3vovA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		4 / 7 GLY A 135
ALA A 181
ALA A 185
VAL A 225
 None
 0.80A 3a2qA-3vovA:
undetectable		 3a2qA-3vovA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 ILE A  76
LEU A  69
THR A  31
VAL A  39
LEU A  43
 None
 1.15A 3a51C-3vovA:
undetectable		 3a51C-3vovA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		4 / 6 VAL A 241
VAL A 240
PHE A 236
ARG A 276
 None
 1.13A 3bjwF-3vovA:
undetectable		 3bjwF-3vovA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		3 / 3 CYH A 171
CYH A 176
HIS A 159
 ZN  A 401 (-2.3A)
ZN  A 401 (-2.3A)
ZN  A 401 (-3.1A)
 0.73A 3dtuB-3vovA:
undetectable		 3dtuB-3vovA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		3 / 3 CYH A 171
CYH A 176
HIS A 159
 ZN  A 401 (-2.3A)
ZN  A 401 (-2.3A)
ZN  A 401 (-3.1A)
 0.70A 3dtuD-3vovA:
undetectable		 3dtuD-3vovA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		4 / 4 LEU A 163
PRO A 167
LEU A 180
ARG A 223
 None
None
None
GOL  A 402 (-3.9A)
 1.39A 3hcoA-3vovA:
2.0		 3hcoA-3vovA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 LEU A 232
TRP A 256
ALA A 221
VAL A 132
GLY A 244
 None
 1.08A 3ln1D-3vovA:
undetectable		 3ln1D-3vovA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 9 GLY A 137
GLY A 138
VAL A 146
ASN A 109
GLU A 178
 None
 1.49A 3owxA-3vovA:
undetectable		 3owxA-3vovA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 VAL A 141
GLY A 143
GLY A 239
SER A 127
ALA A 120
 None
 1.00A 3sufD-3vovA:
undetectable		 3sufD-3vovA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 ARG A 100
GLY A   5
GLY A  62
GLU A  51
ALA A  15
 None
 1.26A 3t7sA-3vovA:
undetectable		 3t7sA-3vovA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 10 ARG A 148
GLY A 144
ALA A 112
VAL A 141
GLU A 105
 None
 1.25A 4da7A-3vovA:
undetectable		 4da7A-3vovA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3vov GLUCOKINASE
(Thermus
thermophilus) 		4 / 7 GLY A 137
GLY A 138
ASN A 109
GLU A 178
 None
 1.12A 4fgkB-3vovA:
undetectable		 4fgkB-3vovA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3vov GLUCOKINASE
(Thermus
thermophilus) 		4 / 7 GLY A 137
GLY A 138
TYR A 129
GLU A 178
 None
 1.04A 4fgkB-3vovA:
undetectable		 4fgkB-3vovA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3vov GLUCOKINASE
(Thermus
thermophilus) 		4 / 5 GLY A 137
GLY A 138
ASN A 109
GLU A 178
 None
 1.19A 4fglC-3vovA:
undetectable		 4fglC-3vovA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 10 LEU A   8
VAL A  29
PRO A  32
THR A  31
ILE A  13
 None
 0.97A 4njuB-3vovA:
undetectable		 4njuB-3vovA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 10 LEU A   8
VAL A  29
PRO A  32
THR A  31
ILE A  13
 None
 0.98A 4njuD-3vovA:
undetectable		 4njuD-3vovA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		6 / 12 LEU A  43
LEU A  94
GLY A  64
ALA A 289
THR A 292
VAL A 102
 None
 1.27A 4nkvB-3vovA:
undetectable		 4nkvB-3vovA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 9 VAL A  27
ILE A  90
VAL A  39
ALA A  40
ALA A  46
 None
 1.16A 4oqrA-3vovA:
undetectable		 4oqrA-3vovA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 9 LEU A   8
GLY A  10
ASN A  81
VAL A  39
VAL A  85
 None
 1.08A 4qd3A-3vovA:
undetectable		 4qd3A-3vovA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 GLY A 244
LEU A 280
GLY A 137
ILE A 136
GLY A 285
 None
 0.95A 5d4uC-3vovA:
undetectable		 5d4uC-3vovA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		6 / 12 LEU A 286
ILE A  82
THR A  65
GLY A  67
ILE A  76
GLY A 288
 None
 1.34A 5d4uD-3vovA:
undetectable		 5d4uD-3vovA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		4 / 5 GLU A  53
GLU A  48
THR A  98
LEU A   6
 None
 0.92A 5hm8G-3vovA:
undetectable		 5hm8G-3vovA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 9 ARG A 148
GLY A 144
ALA A 112
VAL A 141
GLU A 105
 None
 1.27A 5i3cA-3vovA:
2.1		 5i3cA-3vovA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 GLY A 138
VAL A 225
VAL A 242
ALA A 278
LEU A 243
 None
 1.07A 5kocA-3vovA:
undetectable		 5kocA-3vovA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		5 / 12 LEU A 243
GLY A 138
GLY A 137
GLY A 135
ASN A 250
 None
 1.14A 6ce2B-3vovA:
undetectable		 6ce2B-3vovA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3vov GLUCOKINASE
(Thermus
thermophilus) 		3 / 3 ASP A 189
LEU A 217
ARG A 223
 None
None
GOL  A 402 (-3.9A)
 0.89A 7dfrA-3vovA:
undetectable		 7dfrA-3vovA:
20.52