SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vp5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 3vp5 TRANSCRIPTIONAL
REGULATOR
(Lactococcus
lactis) 		3 / 3 PHE A  53
CYH A  21
PHE A  25
 None
 1.05A 3cr5X-3vp5A:
2.0		 3cr5X-3vp5A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 3vp5 TRANSCRIPTIONAL
REGULATOR
(Lactococcus
lactis) 		3 / 3 GLU A 158
GLU A 167
ASN A 168
 None
 0.81A 3lp9B-3vp5A:
undetectable
3lp9D-3vp5A:
undetectable		 3lp9B-3vp5A:
21.46
3lp9D-3vp5A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3vp5 TRANSCRIPTIONAL
REGULATOR
(Lactococcus
lactis) 		3 / 3 TYR A  60
GLU A 118
TYR A 117
 None
 0.90A 3ug8A-3vp5A:
undetectable		 3ug8A-3vp5A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3vp5 TRANSCRIPTIONAL
REGULATOR
(Lactococcus
lactis) 		4 / 7 TYR A   6
GLN A  66
TYR A  18
PHE A  53
 CAC  A 202 (-4.6A)
CAC  A 202 (-4.3A)
CAC  A 202 ( 4.2A)
None
 1.39A 4grqA-3vp5A:
undetectable
4grqC-3vp5A:
undetectable		 4grqA-3vp5A:
19.35
4grqC-3vp5A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 3vp5 TRANSCRIPTIONAL
REGULATOR
(Lactococcus
lactis) 		3 / 3 LEU A 155
SER A 157
PHE A 156
 None
 0.53A 6fgcA-3vp5A:
undetectable		 6fgcA-3vp5A:
16.87