SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vp7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 3vp7 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 30
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 378
ILE A 392
SER A 439
LEU A 363
ILE A 447
 None
 1.16A 3cd2A-3vp7A:
undetectable		 3cd2A-3vp7A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 3vp7 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 30
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 447
ILE A 446
ALA A 368
LEU A 367
LEU A 522
 None
 1.09A 3ozvB-3vp7A:
undetectable		 3ozvB-3vp7A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3vp7 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 30
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 447
ILE A 446
VAL A 526
ILE A 364
 None
 0.58A 3p4wC-3vp7A:
undetectable		 3p4wC-3vp7A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 3vp7 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 30
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 366
LEU A 363
LEU A 360
ALA A 359
ALA A 336
 None
 1.03A 4fn9A-3vp7A:
undetectable		 4fn9A-3vp7A:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 3vp7 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 30
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 364
THR A 443
ILE A 446
ILE A 447
ILE A 450
 None
 0.61A 5murE-3vp7A:
undetectable		 5murE-3vp7A:
17.59