SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vpc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		4 / 4 SER A 235
VAL A 222
PHE A 233
VAL A 268
 None
 1.47A 1o86A-3vpcA:
undetectable		 1o86A-3vpcA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		3 / 3 ASP A 176
GLU A 198
SER A 235
 ADP  A 500 (-2.6A)
None
None
 0.85A 3p2kA-3vpcA:
2.4		 3p2kA-3vpcA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		3 / 3 HIS A 164
ARG A 153
GLU A 154
 None
 0.99A 3qf1A-3vpcA:
undetectable		 3qf1A-3vpcA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		3 / 3 VAL A  83
GLY A  85
LYS A  87
 None
None
ADP  A 500 (-2.7A)
 0.75A 4k50A-3vpcA:
undetectable		 4k50A-3vpcA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		3 / 3 VAL A  83
GLY A  85
LYS A  87
 None
None
ADP  A 500 (-2.7A)
 0.73A 4k50I-3vpcA:
undetectable		 4k50I-3vpcA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		4 / 5 TYR A 275
GLY A 231
GLU A 185
VAL A 214
 None
 1.11A 4nkvD-3vpcA:
undetectable		 4nkvD-3vpcA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLU A 240
ASP A 237
ILE A 236
ALA A 225
VAL A 226
 None
 1.09A 4u8yB-3vpcA:
undetectable		 4u8yB-3vpcA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLU A 240
ASP A 237
ILE A 236
ALA A 225
VAL A 226
 None
 1.10A 4u95B-3vpcA:
undetectable		 4u95B-3vpcA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		4 / 7 ILE A  75
LEU A 272
TYR A 280
GLY A 183
 None
 1.04A 4z69A-3vpcA:
2.1		 4z69A-3vpcA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		5 / 10 ILE A  52
ILE A  81
LEU A  61
ILE A  31
ASN A  32
 None
 1.24A 5vkqA-3vpcA:
undetectable
5vkqD-3vpcA:
undetectable		 5vkqA-3vpcA:
10.05
5vkqD-3vpcA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		5 / 10 ILE A  31
ASN A  32
ILE A  52
ILE A  81
LEU A  61
 None
 1.24A 5vkqA-3vpcA:
undetectable
5vkqB-3vpcA:
undetectable		 5vkqA-3vpcA:
10.05
5vkqB-3vpcA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		5 / 10 ILE A  31
ASN A  32
ILE A  52
ILE A  81
LEU A  61
 None
 1.23A 5vkqC-3vpcA:
undetectable
5vkqD-3vpcA:
undetectable		 5vkqC-3vpcA:
10.05
5vkqD-3vpcA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE
(Sulfurisphaera
tokodaii) 		4 / 8 ILE A 180
TYR A 275
VAL A 226
ASP A 237
 None
 1.11A 5vlmF-3vpcA:
undetectable		 5vlmF-3vpcA:
22.97