SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vpi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3vpi TYPE VI SECRETION
EXPORTED 1
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  77
ALA A  74
PHE A  78
VAL A  94
VAL A  95
 None
 0.98A 1ukbA-3vpiA:
undetectable		 1ukbA-3vpiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 3vpi TYPE VI SECRETION
EXPORTED 1
(Pseudomonas
aeruginosa) 		4 / 7 HIS A  91
GLY A  86
GLY A  90
ASN A  51
 None
 0.77A 2c49B-3vpiA:
undetectable		 2c49B-3vpiA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3vpi TYPE VI SECRETION
EXPORTED 1
(Pseudomonas
aeruginosa) 		3 / 3 VAL A 129
GLN A 121
CYH A 110
 None
 0.82A 5icxA-3vpiA:
undetectable
5icxE-3vpiA:
undetectable		 5icxA-3vpiA:
20.09
5icxE-3vpiA:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 3vpi TYPE VI SECRETION
EXPORTED 1
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  90
GLY A  48
LEU A  84
ASN A 139
ASP A 134
 None
None
None
FMT  A 206 (-3.6A)
None
 1.16A 5yn6A-3vpiA:
undetectable		 5yn6A-3vpiA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 3vpi TYPE VI SECRETION
EXPORTED 1
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  90
GLY A  48
LEU A  84
ASN A 139
ASP A 134
 None
None
None
FMT  A 206 (-3.6A)
None
 1.12A 5yniA-3vpiA:
undetectable		 5yniA-3vpiA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 3vpi TYPE VI SECRETION
EXPORTED 1
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  90
GLY A  48
LEU A  84
ASN A 139
ASP A 134
 None
None
None
FMT  A 206 (-3.6A)
None
 1.14A 5ynmA-3vpiA:
undetectable		 5ynmA-3vpiA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 3vpi TYPE VI SECRETION
EXPORTED 1
(Pseudomonas
aeruginosa) 		4 / 5 HIS A  91
ALA A 114
SER A 112
GLY A 111
 None
 0.99A 5yodB-3vpiA:
undetectable		 5yodB-3vpiA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 3vpi TYPE VI SECRETION
EXPORTED 1
(Pseudomonas
aeruginosa) 		4 / 5 HIS A  91
ALA A 114
SER A 112
GLY A 111
 None
 1.09A 5yodD-3vpiA:
undetectable		 5yodD-3vpiA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3vpi TYPE VI SECRETION
EXPORTED 1
(Pseudomonas
aeruginosa) 		4 / 8 ASP A 136
TYR A 105
GLY A  98
VAL A  95
 None
 1.09A 6giqL-3vpiA:
undetectable
6giqP-3vpiA:
undetectable
6giqT-3vpiA:
undetectable		 6giqL-3vpiA:
15.94
6giqP-3vpiA:
21.62
6giqT-3vpiA:
15.52