SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vpj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B25_B_SAMB602_1 (HYPOTHETICAL PROTEIN)	3vpj	TSE1-SPECIFIC IMMUNITY PROTEIN (Pseudomonas aeruginosa)	3 / 3	GLY E 84 GLU E 105 ASP E 83	None	0.69A	2b25B-3vpjE: undetectable	2b25B-3vpjE: 22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K17_B_OHBB701_0 (LEUCINE-RICH REPEAT-CONTAINING PROTEIN 16A)	3vpj	TSE1-SPECIFIC IMMUNITY PROTEIN (Pseudomonas aeruginosa)	4 / 5	GLU E 112 SER E 130 ARG E 126 SER E 110	None	1.40A	4k17B-3vpjE: 2.1	4k17B-3vpjE: 15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_B_P06B801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	3vpj	TSE1-SPECIFIC IMMUNITY PROTEIN (Pseudomonas aeruginosa)	4 / 7	ILE E 158 GLY E 144 LEU E 102 PHE E 24	None	0.91A	5hieB-3vpjE: undetectable	5hieB-3vpjE: 20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EU9_B_REAB601_1 (RETINOIC ACID RECEPTOR)	3vpj	TSE1-SPECIFIC IMMUNITY PROTEIN (Pseudomonas aeruginosa)	5 / 10	ARG E 100 LEU E 102 GLY E 98 GLY E 41 VAL E 48	None	1.03A	6eu9B-3vpjE: undetectable	6eu9B-3vpjE: 16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EU9_B_REAB601_1 (RETINOIC ACID RECEPTOR)	3vpj	TSE1-SPECIFIC IMMUNITY PROTEIN (Pseudomonas aeruginosa)	5 / 10	ARG E 100 VAL E 101 LEU E 102 GLY E 41 VAL E 48	None	1.07A	6eu9B-3vpjE: undetectable	6eu9B-3vpjE: 16.84

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2B25_B_SAMB602_1","HYPOTHETICAL PROTEIN","3vpj","TSE1-SPECIFIC IMMUNITY PROTEIN","Pseudomonas aeruginosa",3,"GLY E  84;GLU E 105;ASP E  83","None","0.69A","2b25B-3vpjE:undetectable","2b25B-3vpjE:22.42"],["4K17_B_OHBB701_0","LEUCINE-RICH REPEAT-CONTAINING PROTEIN 16A","3vpj","TSE1-SPECIFIC IMMUNITY PROTEIN","Pseudomonas aeruginosa",4,"GLU E 112;SER E 130;ARG E 126;SER E 110","None","1.40A","4k17B-3vpjE:2.1","4k17B-3vpjE:15.54"],["5HIE_B_P06B801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","3vpj","TSE1-SPECIFIC IMMUNITY PROTEIN","Pseudomonas aeruginosa",4,"ILE E 158;GLY E 144;LEU E 102;PHE E  24","None","0.91A","5hieB-3vpjE:undetectable","5hieB-3vpjE:20.52"],["6EU9_B_REAB601_1","RETINOIC ACID RECEPTOR","3vpj","TSE1-SPECIFIC IMMUNITY PROTEIN","Pseudomonas aeruginosa",5,"ARG E 100;LEU E 102;GLY E  98;GLY E  41;VAL E  48","None","1.03A","6eu9B-3vpjE:undetectable","6eu9B-3vpjE:16.84"],["6EU9_B_REAB601_1","RETINOIC ACID RECEPTOR","3vpj","TSE1-SPECIFIC IMMUNITY PROTEIN","Pseudomonas aeruginosa",5,"ARG E 100;VAL E 101;LEU E 102;GLY E  41;VAL E  48","None","1.07A","6eu9B-3vpjE:undetectable","6eu9B-3vpjE:16.84"]]