SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vpq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 5 LEU A 137
GLY A 142
HIS A 143
ILE A 144
 None
PGO  A 311 (-3.2A)
PGO  A 311 ( 4.1A)
None
 0.81A 1xf1A-3vpqA:
undetectable		 1xf1A-3vpqA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 6 LEU A 137
GLY A 142
HIS A 143
ILE A 144
 None
PGO  A 311 (-3.2A)
PGO  A 311 ( 4.1A)
None
 0.85A 1xf1B-3vpqA:
undetectable		 1xf1B-3vpqA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 4 LEU A 163
SER A 101
LEU A 133
LEU A  95
 None
PEG  A 306 (-2.0A)
None
None
 1.08A 1yajA-3vpqA:
undetectable		 1yajA-3vpqA:
18.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 8 TYR A   8
PHE A   9
VAL A  11
TRP A  39
 GSH  A 301 (-4.3A)
GSH  A 301 (-4.3A)
None
GSH  A 301 (-3.5A)
 0.40A 2gssA-3vpqA:
20.5		 2gssA-3vpqA:
31.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 8 TYR A   8
PHE A   9
VAL A  11
TRP A  39
 GSH  A 301 (-4.3A)
GSH  A 301 (-4.3A)
None
GSH  A 301 (-3.5A)
 0.40A 2gssB-3vpqA:
20.5		 2gssB-3vpqA:
31.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 8 TYR A   8
PHE A   9
VAL A  11
TRP A  39
 GSH  A 301 (-4.3A)
GSH  A 301 (-4.3A)
None
GSH  A 301 (-3.5A)
 0.30A 3hjoA-3vpqA:
20.6		 3hjoA-3vpqA:
31.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 7 TYR A   8
PHE A   9
VAL A  11
TRP A  39
 GSH  A 301 (-4.3A)
GSH  A 301 (-4.3A)
None
GSH  A 301 (-3.5A)
 0.36A 3kmoB-3vpqA:
20.4		 3kmoB-3vpqA:
31.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 8 TYR A   8
PHE A   9
VAL A  11
TRP A  39
 GSH  A 301 (-4.3A)
GSH  A 301 (-4.3A)
None
GSH  A 301 (-3.5A)
 0.42A 3n9jA-3vpqA:
20.5		 3n9jA-3vpqA:
31.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 5 PHE A 128
ILE A 136
LEU A 133
LYS A 132
 None
PGO  A 303 ( 4.3A)
None
PGO  A 309 (-2.7A)
 1.26A 3sueC-3vpqA:
undetectable		 3sueC-3vpqA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 5 PHE A 129
PHE A 130
LEU A 137
PRO A 182
 PEG  A 306 ( 4.5A)
None
None
None
 1.13A 4o8zA-3vpqA:
undetectable		 4o8zA-3vpqA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 6 ILE A  88
ASP A  89
ARG A  69
GLY A  72
 None
 0.68A 4oltA-3vpqA:
undetectable		 4oltA-3vpqA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 6 ILE A  88
ASP A  89
ARG A  69
GLY A  72
 None
 0.72A 4oltB-3vpqA:
undetectable		 4oltB-3vpqA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3vpq GLUTATHIONE
S-TRANSFERASE SIGMA
(Bombyx
mori) 		4 / 6 PHE A   9
PRO A  10
ARG A  19
ILE A  34
 GSH  A 301 (-4.3A)
None
None
None
 1.39A 5ih0A-3vpqA:
undetectable		 5ih0A-3vpqA:
23.86