SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vpr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 3vpr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 9 LEU A 130
ILE A 129
LEU A 155
GLY A  66
ALA A  78
 None
 1.22A 1e7aA-3vprA:
3.4		 1e7aA-3vprA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3vpr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 10 ILE A  50
ALA A  13
LEU A  57
ILE A   8
THR A  99
 None
 1.22A 1rb3A-3vprA:
undetectable		 1rb3A-3vprA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 3vpr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 10 ILE A 181
ALA A 147
LEU A  79
LEU A 130
VAL A 142
 None
 1.18A 3o02A-3vprA:
undetectable
3o02B-3vprA:
2.0		 3o02A-3vprA:
21.02
3o02B-3vprA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL3_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3vpr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 12 ILE A  50
ALA A  13
LEU A  57
ILE A   8
THR A  99
 None
 1.22A 3ql3A-3vprA:
undetectable		 3ql3A-3vprA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3vpr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 7 ASN A 111
SER A  55
ILE A  54
LEU A  51
LEU A 107
 None
 1.40A 5u4sA-3vprA:
undetectable		 5u4sA-3vprA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 3vpr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 11 GLU A  84
GLY A  66
ALA A  65
ALA A  69
ILE A 129
 None
 1.04A 5yk2A-3vprA:
2.2		 5yk2A-3vprA:
21.38