SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vpy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL
(Arabidopsis
thaliana) 		5 / 12 SER A 122
PHE A 119
TYR A 126
LEU A  41
LEU A  90
 None
 1.34A 1p33A-3vpyA:
undetectable		 1p33A-3vpyA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL
(Arabidopsis
thaliana) 		5 / 12 SER A 122
PHE A 119
TYR A 126
LEU A  41
LEU A  90
 None
 1.39A 1p33B-3vpyA:
undetectable		 1p33B-3vpyA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL
(Arabidopsis
thaliana) 		5 / 12 HIS A  62
THR A  53
ILE A  51
GLY A 120
THR A  96
 None
 0.85A 1utdL-3vpyA:
undetectable
1utdM-3vpyA:
undetectable		 1utdL-3vpyA:
26.74
1utdM-3vpyA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL
(Arabidopsis
thaliana) 		5 / 11 GLY A 120
THR A  96
HIS A  62
THR A  53
ILE A  51
 None
 0.85A 1utdL-3vpyA:
undetectable
1utdV-3vpyA:
undetectable		 1utdL-3vpyA:
26.74
1utdV-3vpyA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL
(Arabidopsis
thaliana) 		4 / 6 LEU A  19
TYR A 126
ILE A 117
GLY A  43
 None
 0.94A 2du8A-3vpyA:
undetectable		 2du8A-3vpyA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL
(Arabidopsis
thaliana) 		4 / 6 LEU A  19
TYR A 126
ILE A 117
GLY A  43
 None
 0.94A 2du8B-3vpyA:
undetectable		 2du8B-3vpyA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL
(Arabidopsis
thaliana) 		4 / 6 ASP A 115
ILE A 117
LEU A  19
TYR A  67
 None
 0.97A 2ya7A-3vpyA:
undetectable		 2ya7A-3vpyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL
(Arabidopsis
thaliana) 		4 / 6 ASP A 115
ILE A 117
LEU A  19
TYR A  67
 None
 1.01A 2ya7B-3vpyA:
undetectable		 2ya7B-3vpyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL
(Arabidopsis
thaliana) 		4 / 6 ASP A 115
ILE A 117
LEU A  19
TYR A  67
 None
 1.02A 2ya7D-3vpyA:
2.4		 2ya7D-3vpyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL
(Arabidopsis
thaliana) 		4 / 8 SER A 122
PHE A 119
TYR A 126
LEU A  90
 None
 1.09A 3jq7B-3vpyA:
undetectable		 3jq7B-3vpyA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL
(Arabidopsis
thaliana) 		3 / 3 ALA A  10
ARG A  11
LYS A  81
 None
 1.01A 3kp3B-3vpyA:
undetectable		 3kp3B-3vpyA:
20.83