SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
3vqi ATG5
(Kluyveromyces
marxianus)
5 / 12 TYR A 267
ILE A 262
VAL A  88
ILE A  13
MET A  39
None
1.13A 1xozA-3vqiA:
undetectable
1xozA-3vqiA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)
3vqi ATG5
(Kluyveromyces
marxianus)
4 / 5 ASP A  42
SER A 261
LEU A  89
GLY A  87
None
1.08A 2j2pA-3vqiA:
undetectable
2j2pB-3vqiA:
undetectable
2j2pA-3vqiA:
18.91
2j2pB-3vqiA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3vqi ATG5
(Kluyveromyces
marxianus)
4 / 8 ILE A  13
VAL A  38
CYH A  86
TYR A  48
None
0.96A 2xz5A-3vqiA:
undetectable
2xz5C-3vqiA:
undetectable
2xz5A-3vqiA:
19.79
2xz5C-3vqiA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3vqi ATG5
(Kluyveromyces
marxianus)
4 / 8 ILE A  13
VAL A  38
CYH A  86
TYR A  48
None
0.96A 2xz5C-3vqiA:
undetectable
2xz5D-3vqiA:
undetectable
2xz5C-3vqiA:
19.79
2xz5D-3vqiA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)
3vqi ATG5
(Kluyveromyces
marxianus)
5 / 12 SER A 261
PRO A  85
GLY A  87
LEU A 255
ASP A 250
None
1.47A 3r24A-3vqiA:
undetectable
3r24A-3vqiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3vqi ATG5
(Kluyveromyces
marxianus)
4 / 8 VAL A  38
CYH A  86
TYR A  48
ILE A  13
None
0.96A 4aftD-3vqiA:
undetectable
4aftE-3vqiA:
undetectable
4aftD-3vqiA:
19.79
4aftE-3vqiA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3vqi ATG5
(Kluyveromyces
marxianus)
4 / 8 VAL A  38
CYH A  86
TYR A  48
ILE A  13
None
0.91A 4bqtC-3vqiA:
undetectable
4bqtD-3vqiA:
undetectable
4bqtC-3vqiA:
19.79
4bqtD-3vqiA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)
3vqi ATG5
(Kluyveromyces
marxianus)
5 / 12 PHE A 253
ASN A 251
LEU A 151
PHE A 189
ASP A 257
None
1.39A 4pevC-3vqiA:
undetectable
4pevC-3vqiA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_A_ACTA403_0
(3C-LIKE PROTEINASE)
3vqi ATG5
(Kluyveromyces
marxianus)
4 / 5 TYR A 256
SER A 261
LEU A 266
GLN A 242
None
1.47A 4yo9A-3vqiA:
undetectable
4yo9B-3vqiA:
undetectable
4yo9A-3vqiA:
21.78
4yo9B-3vqiA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)
3vqi ATG5
(Kluyveromyces
marxianus)
3 / 3 TRP A 144
ILE A 173
SER A 172
None
0.98A 5gqbA-3vqiA:
undetectable
5gqbA-3vqiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)
3vqi ATG5
(Kluyveromyces
marxianus)
4 / 7 SER A 228
ILE A 229
LEU A 225
LEU A 220
None
0.83A 5u4sA-3vqiA:
undetectable
5u4sA-3vqiA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)
3vqi ATG5
(Kluyveromyces
marxianus)
4 / 8 SER A 228
ILE A 229
LEU A 225
LEU A 220
None
0.82A 5u4sB-3vqiA:
undetectable
5u4sB-3vqiA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)
3vqi ATG5
(Kluyveromyces
marxianus)
5 / 12 HIS A 133
PHE A  47
LEU A 116
VAL A  17
THR A  51
None
1.37A 6brdA-3vqiA:
undetectable
6brdA-3vqiA:
17.04