SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V04_B_0LIB1771_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	3vql	SMALL HEAT SHOCK PROTEIN STHSP14.0 (Sulfurisphaera tokodaii)	5 / 12	ALA A 64 VAL A 83 ALA A 52 ALA A 40 ASP A 41	None	0.93A	4v04B-3vqlA: undetectable	4v04B-3vqlA: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B2S_A_ACTA107_0 (CRISPR-ASSOCIATED ENDONUCLEASE CAS9 GUIDE RNA)	3vql	SMALL HEAT SHOCK PROTEIN STHSP14.0 (Sulfurisphaera tokodaii)	3 / 3	VAL A 37 THR A 109 ARG A 111	None	0.70A	5b2sB-3vqlA: undetectable	5b2sB-3vqlA: 7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B2T_A_ACTA108_0 (CRISPR-ASSOCIATED ENDONUCLEASE CAS9 GUIDE RNA)	3vql	SMALL HEAT SHOCK PROTEIN STHSP14.0 (Sulfurisphaera tokodaii)	3 / 3	VAL A 37 THR A 109 ARG A 111	None	0.72A	5b2tB-3vqlA: undetectable	5b2tB-3vqlA: 7.41