SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vrc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3vrc CYTOCHROME C'
(Thermochromatium
tepidum) 		4 / 6 ALA A  73
TYR A  16
TYR A  58
ILE A   9
 HEC  A 200 ( 4.1A)
HEC  A 200 (-3.6A)
None
HEC  A 200 ( 4.7A)
 1.21A 2dcfA-3vrcA:
undetectable		 2dcfA-3vrcA:
16.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 3vrc CYTOCHROME C'
(Thermochromatium
tepidum) 		4 / 5 ALA A  20
GLY A 118
CYH A 121
HIS A 125
 HEC  A 200 ( 3.8A)
None
HEC  A 200 (-1.9A)
HEC  A 200 (-3.3A)
 0.17A 2yldA-3vrcA:
17.2		 2yldA-3vrcA:
30.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 3vrc CYTOCHROME C'
(Thermochromatium
tepidum) 		4 / 5 ALA A  20
GLY A 118
CYH A 121
HIS A 125
 HEC  A 200 ( 3.8A)
None
HEC  A 200 (-1.9A)
HEC  A 200 (-3.3A)
 0.23A 2ylgA-3vrcA:
17.4		 2ylgA-3vrcA:
30.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3vrc CYTOCHROME C'
(Thermochromatium
tepidum) 		4 / 7 ASN A  22
ALA A  47
ALA A  48
ALA A  50
 None
 0.85A 3a2qA-3vrcA:
undetectable		 3a2qA-3vrcA:
13.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 3vrc CYTOCHROME C'
(Thermochromatium
tepidum) 		4 / 5 ALA A  20
GLY A 118
CYH A 121
HIS A 125
 HEC  A 200 ( 3.8A)
None
HEC  A 200 (-1.9A)
HEC  A 200 (-3.3A)
 0.18A 3zwiA-3vrcA:
17.2		 3zwiA-3vrcA:
30.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 3vrc CYTOCHROME C'
(Thermochromatium
tepidum) 		4 / 4 ALA A  20
GLY A 118
CYH A 121
HIS A 125
 HEC  A 200 ( 3.8A)
None
HEC  A 200 (-1.9A)
HEC  A 200 (-3.3A)
 0.19A 4cipA-3vrcA:
17.3		 4cipA-3vrcA:
30.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 3vrc CYTOCHROME C'
(Thermochromatium
tepidum) 		4 / 5 ALA A  20
GLY A 118
CYH A 121
HIS A 125
 HEC  A 200 ( 3.8A)
None
HEC  A 200 (-1.9A)
HEC  A 200 (-3.3A)
 0.25A 5jliA-3vrcA:
17.3		 5jliA-3vrcA:
30.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 3vrc CYTOCHROME C'
(Thermochromatium
tepidum) 		4 / 4 ALA A  20
GLY A 118
CYH A 121
HIS A 125
 HEC  A 200 ( 3.8A)
None
HEC  A 200 (-1.9A)
HEC  A 200 (-3.3A)
 0.18A 5jslA-3vrcA:
17.5		 5jslA-3vrcA:
30.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 3vrc CYTOCHROME C'
(Thermochromatium
tepidum) 		4 / 5 ALA A  20
GLY A 118
CYH A 121
HIS A 125
 HEC  A 200 ( 3.8A)
None
HEC  A 200 (-1.9A)
HEC  A 200 (-3.3A)
 0.21A 5jt4A-3vrcA:
17.2		 5jt4A-3vrcA:
30.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3vrc CYTOCHROME C'
(Thermochromatium
tepidum) 		4 / 6 ASN A  65
ARG A  72
ILE A   9
GLU A   6
 None
None
HEC  A 200 ( 4.7A)
None
 1.17A 5uigA-3vrcA:
5.3		 5uigA-3vrcA:
19.09