SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vrd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		4 / 7 GLN A  43
ILE A  49
ARG A 141
PHE A 136
 HEC  A 202 ( 4.6A)
None
HEC  A 202 ( 3.0A)
HEC  A 202 (-4.5A)
 1.20A 1e71M-3vrdA:
undetectable		 1e71M-3vrdA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		4 / 7 GLN A  43
ILE A  49
ARG A 141
PHE A 136
 HEC  A 202 ( 4.6A)
None
HEC  A 202 ( 3.0A)
HEC  A 202 (-4.5A)
 1.17A 1e72M-3vrdA:
undetectable		 1e72M-3vrdA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		4 / 6 GLN A  43
ILE A  49
ARG A 141
PHE A 136
 HEC  A 202 ( 4.6A)
None
HEC  A 202 ( 3.0A)
HEC  A 202 (-4.5A)
 1.21A 1e73M-3vrdA:
undetectable		 1e73M-3vrdA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum;
Thermochromatium
tepidum) 		4 / 7 GLY A  55
ALA B 350
ILE A  57
SER B 348
 None
None
HEC  A 201 ( 4.4A)
None
 0.76A 1gtnA-3vrdA:
undetectable
1gtnK-3vrdA:
undetectable		 1gtnA-3vrdA:
19.33
1gtnK-3vrdA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 11 LEU B 141
ILE B 250
ILE B 151
MET B 144
GLN B 140
 None
 1.41A 1gx9A-3vrdB:
undetectable		 1gx9A-3vrdB:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		4 / 5 TYR B  39
PRO B  35
THR B 399
THR B  16
 FAD  B 501 (-4.6A)
FAD  B 501 (-4.4A)
None
None
 1.41A 1ymxB-3vrdB:
undetectable		 1ymxB-3vrdB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		4 / 8 GLY B   9
THR B  16
ALA B  17
ALA B  18
 FAD  B 501 (-3.4A)
None
None
None
 0.49A 2ej3A-3vrdB:
undetectable		 2ej3A-3vrdB:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 12 ALA B 153
ILE B 151
ALA B 127
LEU B 136
ILE B  49
 None
 1.14A 2h42B-3vrdB:
undetectable		 2h42B-3vrdB:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 12 GLY B  11
PRO B 104
GLY B 105
ALA B  15
LEU B  65
 FAD  B 501 (-3.2A)
FAD  B 501 (-4.8A)
FAD  B 501 (-3.3A)
None
None
 0.91A 2plwA-3vrdB:
undetectable		 2plwA-3vrdB:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		5 / 9 ILE A  29
ASP B 398
GLY A  16
TYR B  20
THR B 336
 HEC  A 201 ( 4.3A)
None
None
None
HEC  A 201 (-3.3A)
 1.49A 2tsrD-3vrdA:
undetectable		 2tsrD-3vrdA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		4 / 8 HIS B 389
ILE B 395
MET B  44
ALA A  25
 None
 0.90A 2x0pA-3vrdB:
undetectable		 2x0pA-3vrdB:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 11 GLY B   9
GLY B  10
ILE B  33
GLU B  34
ALA B  77
 FAD  B 501 (-3.4A)
FAD  B 501 ( 4.9A)
FAD  B 501 (-4.9A)
FAD  B 501 (-2.7A)
FAD  B 501 (-3.8A)
 0.98A 3dxyA-3vrdB:
undetectable		 3dxyA-3vrdB:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum;
Thermochromatium
tepidum) 		3 / 3 TYR B 306
ASP B 398
HIS A  15
 None
None
HEC  A 201 (-3.2A)
 0.72A 3e23A-3vrdB:
1.8		 3e23A-3vrdB:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 12 VAL B   8
ALA B  17
ALA B  18
ALA B 316
VAL B  87
 FAD  B 501 (-4.6A)
None
None
None
None
 0.73A 3fc6C-3vrdB:
undetectable		 3fc6C-3vrdB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		6 / 12 VAL B   8
GLY B   9
GLY B  11
GLU B  34
ALA B  77
ILE B 261
 FAD  B 501 (-4.6A)
FAD  B 501 (-3.4A)
FAD  B 501 (-3.2A)
FAD  B 501 (-2.7A)
FAD  B 501 (-3.8A)
FAD  B 501 (-3.6A)
 0.93A 3fuuA-3vrdB:
2.3		 3fuuA-3vrdB:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		4 / 7 TYR A  72
ASN A   9
PHE A  37
MET A  41
 None
None
HEC  A 201 (-4.6A)
HEC  A 201 (-3.6A)
 1.27A 3tvxB-3vrdA:
undetectable		 3tvxB-3vrdA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 12 ILE B 347
GLY B 203
ILE B 217
VAL B 185
ASN B  46
 None
None
None
None
FAD  B 501 ( 3.6A)
 1.24A 4a81A-3vrdB:
undetectable		 4a81A-3vrdB:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		4 / 7 GLU B 167
ILE B 340
GLU B  47
VAL B  60
 None
 0.85A 4a97A-3vrdB:
undetectable		 4a97A-3vrdB:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		4 / 7 GLU B 167
ILE B 340
GLU B  47
VAL B  60
 None
 0.88A 4a97D-3vrdB:
undetectable		 4a97D-3vrdB:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		4 / 7 GLU B 167
ILE B 340
GLU B  47
VAL B  60
 None
 0.90A 4a97H-3vrdB:
undetectable		 4a97H-3vrdB:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		3 / 3 TYR B  40
THR B  38
GLU B 132
 None
 0.77A 4df3A-3vrdB:
3.6		 4df3A-3vrdB:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		3 / 3 TYR B  40
THR B  38
GLU B 132
 None
 0.79A 4df3B-3vrdB:
undetectable		 4df3B-3vrdB:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		4 / 6 ARG B 168
GLY B 164
GLU B 167
GLN B 256
 FAD  B 501 (-4.2A)
FAD  B 501 ( 4.6A)
None
None
 1.08A 4g0vB-3vrdB:
undetectable		 4g0vB-3vrdB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 11 GLN B 311
ALA B 312
ALA B 315
ALA B 316
VAL B  30
 None
 1.02A 4j6cA-3vrdB:
undetectable		 4j6cA-3vrdB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 11 GLN B 311
ALA B 312
ALA B 315
VAL B  30
LEU B  32
 None
 1.10A 4j6cA-3vrdB:
undetectable		 4j6cA-3vrdB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 10 GLN B 311
ALA B 312
ALA B 315
ALA B 316
VAL B  30
 None
 1.05A 4j6cB-3vrdB:
undetectable		 4j6cB-3vrdB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 10 GLN B 311
ALA B 312
ALA B 315
VAL B  30
LEU B  32
 None
 1.11A 4j6cB-3vrdB:
undetectable		 4j6cB-3vrdB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 12 GLN B 311
ALA B 312
ALA B 315
ALA B 316
VAL B  30
 None
 1.10A 4j6dA-3vrdB:
undetectable		 4j6dA-3vrdB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 12 GLN B 311
ALA B 312
ALA B 315
ALA B 316
VAL B  30
 None
 1.12A 4j6dB-3vrdB:
undetectable		 4j6dB-3vrdB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 12 GLN B 311
ALA B 312
ALA B 315
ALA B 316
VAL B  30
 None
 1.06A 4jbtA-3vrdB:
undetectable		 4jbtA-3vrdB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 11 GLN B 311
ALA B 312
ALA B 315
ALA B 316
VAL B  30
 None
 1.06A 4jbtB-3vrdB:
undetectable		 4jbtB-3vrdB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		4 / 4 VAL B 228
THR B 239
GLU B 238
GLU B 243
 None
 1.31A 4l78A-3vrdB:
undetectable		 4l78A-3vrdB:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 10 ALA B  24
ILE B  28
VAL B  30
ALA B  17
ALA B 316
 None
 1.05A 4lbgA-3vrdB:
undetectable		 4lbgA-3vrdB:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N6P_A_JMSA713_1
(LACTOTRANSFERRIN)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		4 / 4 HIS B 389
ALA B 388
VAL B 385
GLU B 167
 None
 1.29A 4n6pA-3vrdB:
undetectable		 4n6pA-3vrdB:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 9 ALA B 173
ILE B  49
ILE B 340
ILE B 187
VAL B 185
 None
 1.06A 4nptA-3vrdB:
undetectable		 4nptA-3vrdB:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 12 LEU B  58
THR B 134
ALA B 127
ASN B  46
CYH B 161
 None
None
None
FAD  B 501 ( 3.6A)
FAD  B 501 (-3.3A)
 1.45A 5dsgB-3vrdB:
undetectable		 5dsgB-3vrdB:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		4 / 6 TYR B 208
ASP B  52
HIS B 174
ILE B  49
 None
 1.10A 5ih0A-3vrdB:
undetectable		 5ih0A-3vrdB:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		3 / 3 TYR B 338
TYR B 353
SER B 307
 HEC  A 201 ( 4.8A)
None
None
 0.94A 5iktB-3vrdB:
undetectable		 5iktB-3vrdB:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		4 / 4 SER A 172
ALA A 171
GLN A 124
THR A 126
 None
 1.28A 5n0rA-3vrdA:
undetectable		 5n0rA-3vrdA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		4 / 4 SER A 172
ALA A 171
GLN A 124
THR A 126
 None
 1.28A 5n0sA-3vrdA:
undetectable		 5n0sA-3vrdA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		4 / 4 SER A 172
ALA A 171
GLN A 124
THR A 126
 None
 1.25A 5n0wA-3vrdA:
undetectable		 5n0wA-3vrdA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		4 / 5 SER A 172
ALA A 171
GLN A 124
THR A 126
 None
 1.25A 5n0wB-3vrdA:
undetectable		 5n0wB-3vrdA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		4 / 4 SER A 172
ALA A 171
GLN A 124
THR A 126
 None
 1.31A 5n0xA-3vrdA:
undetectable		 5n0xA-3vrdA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3vrd FLAVOCYTOCHROME C
HEME SUBUNIT
(Thermochromatium
tepidum) 		4 / 5 SER A 172
ALA A 171
GLN A 124
THR A 126
 None
 1.28A 5n4iA-3vrdA:
undetectable		 5n4iA-3vrdA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 12 ALA B 315
PRO B 331
GLY B 329
SER B 310
ALA B  17
 None
 1.17A 5zvgA-3vrdB:
2.8		 5zvgA-3vrdB:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT
(Thermochromatium
tepidum) 		5 / 12 ALA B 315
PRO B 331
GLY B 329
SER B 310
ALA B  17
 None
 1.17A 5zvgB-3vrdB:
2.7		 5zvgB-3vrdB:
25.05