SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vsk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
LYS A 395
SER A 448
ASN A 450
LYS A 618
GLY A 620
 None
 0.67A 1ghmA-3vskA:
15.7		 1ghmA-3vskA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
LYS A 395
ASN A 450
THR A 603
LYS A 618
GLY A 620
 None
 0.72A 1i2wA-3vskA:
16.2		 1i2wA-3vskA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
ASN A 450
THR A 603
LYS A 618
GLY A 620
 None
 0.56A 1i2wA-3vskA:
16.2		 1i2wA-3vskA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
LYS A 395
SER A 448
ASN A 450
GLY A 391
ALA A 622
 None
 1.48A 1i2wB-3vskA:
16.3		 1i2wB-3vskA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
LYS A 395
SER A 448
ASN A 450
THR A 603
GLY A 620
 None
 0.72A 1i2wB-3vskA:
16.3		 1i2wB-3vskA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 4 ALA A 190
ARG A 186
GLN A 197
GLU A 187
 None
 1.23A 1lqtB-3vskA:
undetectable		 1lqtB-3vskA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 4 ALA A 190
ARG A 186
GLN A 197
GLU A 187
 None
 1.25A 1lquB-3vskA:
undetectable		 1lquB-3vskA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 LEU A 486
GLY A 397
GLY A 396
LEU A 445
ILE A 522
 None
 0.90A 1mx1D-3vskA:
undetectable		 1mx1D-3vskA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		7 / 12 SER A 392
LYS A 395
SER A 448
ASN A 450
THR A 603
LYS A 618
GLY A 620
 None
 0.66A 1ymxA-3vskA:
16.7		 1ymxA-3vskA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
LYS A 395
SER A 448
ASN A 450
LYS A 618
GLY A 620
 None
 0.65A 1ymxB-3vskA:
16.9		 1ymxB-3vskA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 7 LEU A 471
GLN A 422
LEU A 518
PHE A 454
 None
 1.03A 2eimC-3vskA:
undetectable
2eimJ-3vskA:
undetectable		 2eimC-3vskA:
16.33
2eimJ-3vskA:
6.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 6 LEU A 471
GLN A 422
LEU A 518
PHE A 454
 None
 1.12A 2einP-3vskA:
undetectable
2einW-3vskA:
undetectable		 2einP-3vskA:
16.33
2einW-3vskA:
6.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 7 TRP A 129
GLN A 145
TYR A 158
ILE A 166
 None
 1.33A 2ph9A-3vskA:
undetectable
2ph9B-3vskA:
undetectable		 2ph9A-3vskA:
18.15
2ph9B-3vskA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 11 LEU A 365
GLN A 355
ILE A 241
LEU A 499
ASP A 498
 None
 1.20A 2q6hA-3vskA:
undetectable		 2q6hA-3vskA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 11 LEU A 365
GLN A 355
ILE A 241
LEU A 499
ASP A 498
 None
 1.20A 2q72A-3vskA:
undetectable		 2q72A-3vskA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 11 LEU A 365
GLN A 355
ILE A 241
LEU A 499
ASP A 498
 None
 1.17A 2qeiA-3vskA:
undetectable		 2qeiA-3vskA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		3 / 3 PRO A  68
ASN A  83
ARG A 230
 None
 0.99A 2qeuB-3vskA:
undetectable		 2qeuB-3vskA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 11 LEU A 365
GLN A 355
ILE A 241
LEU A 499
ASP A 498
 None
 1.14A 2qjuA-3vskA:
undetectable		 2qjuA-3vskA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 11 SER A 448
THR A 621
SER A 392
SER A 429
PHE A 454
 None
 1.25A 2xf3A-3vskA:
15.4		 2xf3A-3vskA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 11 SER A 448
THR A 621
SER A 392
SER A 429
PHE A 454
 None
 1.22A 2xf3B-3vskA:
15.3		 2xf3B-3vskA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_A_ADNA439_1
(ADENOSYLHOMOCYSTEINA
SE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 10 LEU A 531
GLN A 548
THR A 495
GLY A 573
HIS A 550
 None
 1.23A 3h9uA-3vskA:
undetectable		 3h9uA-3vskA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 10 LEU A 531
GLN A 548
THR A 495
GLY A 573
HIS A 550
 None
 1.29A 3h9uC-3vskA:
undetectable		 3h9uC-3vskA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 10 LEU A 531
GLN A 548
THR A 495
GLY A 573
HIS A 550
 None
 1.28A 3h9uD-3vskA:
undetectable		 3h9uD-3vskA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 SER A 448
ASN A 450
THR A 603
LYS A 618
GLY A 620
 None
 0.51A 3hlwA-3vskA:
16.8		 3hlwA-3vskA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 448
ASN A 450
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.63A 3hlwB-3vskA:
16.9		 3hlwB-3vskA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 4 ILE A 571
ARG A  69
ILE A 555
THR A 319
 None
 1.23A 3ia4C-3vskA:
undetectable		 3ia4C-3vskA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 8 GLN A 170
LEU A 182
LEU A 179
ILE A 120
 None
 0.87A 3nbqB-3vskA:
undetectable		 3nbqB-3vskA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 8 GLN A 170
LEU A 182
LEU A 179
ILE A 120
 None
 0.83A 3nbqC-3vskA:
undetectable		 3nbqC-3vskA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.66A 3ny4A-3vskA:
16.9		 3ny4A-3vskA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 LYS A 395
SER A 448
ASN A 450
LYS A 618
GLY A 620
 None
 0.62A 3q07B-3vskA:
16.8		 3q07B-3vskA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
ASN A 450
LYS A 618
THR A 619
GLY A 620
 None
 0.63A 3sh8A-3vskA:
16.7		 3sh8A-3vskA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 ASN A 359
ILE A 362
GLY A 573
THR A 319
GLY A 496
 None
 1.05A 3vaqA-3vskA:
undetectable		 3vaqA-3vskA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 11 GLN A 404
ALA A 401
LEU A 486
ASN A 581
ILE A 586
 None
 1.14A 4claA-3vskA:
undetectable		 4claA-3vskA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 7 ILE A  72
ARG A 230
ARG A  71
VAL A 564
 None
 1.33A 4f4dA-3vskA:
undetectable		 4f4dA-3vskA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 10 SER A 448
ASN A 450
LYS A 618
THR A 619
GLY A 620
 None
 0.87A 4fh2A-3vskA:
17.2		 4fh2A-3vskA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 LEU A 276
TYR A 280
PRO A 549
ASP A  74
ASP A 321
 None
 1.42A 4j7xJ-3vskA:
undetectable		 4j7xJ-3vskA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 9 GLY A 391
SER A 392
SER A 448
GLY A 620
THR A 635
 None
 1.49A 4lb0A-3vskA:
undetectable		 4lb0A-3vskA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 LEU A 400
VAL A 579
ILE A 586
GLN A 590
ILE A 589
 None
 0.94A 4ltwA-3vskA:
undetectable		 4ltwA-3vskA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
ASN A 450
LYS A 618
THR A 619
GLY A 620
 None
 0.67A 4n9kA-3vskA:
16.5		 4n9kA-3vskA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 PHE A 421
PRO A 514
PHE A 454
THR A 456
SER A 521
 None
 1.44A 4olfA-3vskA:
undetectable		 4olfA-3vskA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 448
ASN A 450
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.76A 4pm5A-3vskA:
16.8		 4pm5A-3vskA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 LYS A 395
SER A 448
ASN A 450
THR A 603
LYS A 618
GLY A 620
 None
 0.81A 4pm7A-3vskA:
16.7		 4pm7A-3vskA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 448
ASN A 450
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.74A 4pm9A-3vskA:
17.1		 4pm9A-3vskA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 8 LEU A 399
GLY A 396
MET A 595
ALA A 616
 None
 0.86A 4rjdA-3vskA:
undetectable
4rjdB-3vskA:
undetectable		 4rjdA-3vskA:
6.94
4rjdB-3vskA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 7 VAL A 390
THR A 635
LEU A 491
VAL A 537
 None
 0.94A 5e4dA-3vskA:
undetectable
5e4dB-3vskA:
undetectable		 5e4dA-3vskA:
14.66
5e4dB-3vskA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 ALA A  46
LEU A  73
ILE A 320
GLY A 552
LEU A 284
 None
 1.13A 5fsaA-3vskA:
undetectable		 5fsaA-3vskA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 11 SER A 392
SER A 448
ASN A 450
LYS A 618
THR A 619
GLY A 620
 None
 0.66A 5ghzA-3vskA:
16.6		 5ghzA-3vskA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 10 SER A 392
SER A 448
ASN A 450
LYS A 618
THR A 619
GLY A 620
 None
 0.65A 5ghzB-3vskA:
16.6		 5ghzB-3vskA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 6 GLY A 367
ASN A 349
MET A 351
ILE A 381
 None
 1.16A 5j4nA-3vskA:
undetectable		 5j4nA-3vskA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 10 VAL A  81
ILE A  72
LEU A 318
GLY A 240
PHE A 242
 None
 1.17A 5mxbA-3vskA:
undetectable		 5mxbA-3vskA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.77A 6b5yB-3vskA:
16.9		 6b5yB-3vskA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.82A 6b5yD-3vskA:
17.2		 6b5yD-3vskA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.62A 6b68B-3vskA:
16.9		 6b68B-3vskA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 SER A 392
SER A 448
THR A 603
LYS A 618
GLY A 620
 None
 0.50A 6b68D-3vskA:
17.0		 6b68D-3vskA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.60A 6b69A-3vskA:
17.1
6b69B-3vskA:
16.9		 6b69A-3vskA:
9.00
6b69B-3vskA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.60A 6b69D-3vskA:
16.6		 6b69D-3vskA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.59A 6b6aB-3vskA:
16.8		 6b6aB-3vskA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.75A 6b6dA-3vskA:
16.7		 6b6dA-3vskA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		6 / 12 SER A 392
SER A 448
THR A 603
LYS A 618
THR A 619
GLY A 620
 None
 0.64A 6b6eA-3vskA:
16.8		 6b6eA-3vskA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 12 SER A 448
ASN A 450
THR A 603
LYS A 618
GLY A 620
 None
 0.46A 6c79A-3vskA:
16.6		 6c79A-3vskA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		5 / 11 THR A 247
SER A 225
ALA A  88
THR A  90
THR A  92
 None
 1.27A 6efnA-3vskA:
0.0		 6efnA-3vskA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 3vsk PENICILLIN-BINDING
PROTEIN 3
(Staphylococcus
aureus) 		4 / 5 GLY A 592
LEU A 445
TYR A 403
GLN A 588
 None
 1.30A 6ji6A-3vskA:
undetectable		 6ji6A-3vskA:
15.19