SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vsm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 TRP A 176
PHE A 123
TYR A 220
VAL A 126
 None
 1.23A 1ibgH-3vsmA:
undetectable		 1ibgH-3vsmA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 TYR A 288
TYR A 297
ILE A 328
GLY A 281
 None
 1.31A 1kifA-3vsmA:
undetectable		 1kifA-3vsmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 TYR A 288
TYR A 297
ILE A 328
GLY A 281
 None
 1.31A 1kifB-3vsmA:
undetectable		 1kifB-3vsmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 TYR A 288
TYR A 297
ILE A 328
GLY A 281
 None
 1.31A 1kifC-3vsmA:
undetectable		 1kifC-3vsmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 TYR A 288
TYR A 297
ILE A 328
GLY A 281
 None
 1.31A 1kifD-3vsmA:
undetectable		 1kifD-3vsmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 TYR A 288
TYR A 297
ILE A 328
GLY A 281
 None
 1.31A 1kifE-3vsmA:
undetectable		 1kifE-3vsmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 TYR A 288
TYR A 297
ILE A 328
GLY A 281
 None
 1.31A 1kifF-3vsmA:
undetectable		 1kifF-3vsmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 TYR A 288
TYR A 297
ILE A 328
GLY A 281
 None
 1.31A 1kifG-3vsmA:
undetectable		 1kifG-3vsmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 TYR A 288
TYR A 297
ILE A 328
GLY A 281
 None
 1.31A 1kifH-3vsmA:
undetectable		 1kifH-3vsmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 SER A 115
THR A 109
ASN A 113
ASP A 112
 None
 1.38A 1mxdA-3vsmA:
undetectable		 1mxdA-3vsmA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 11 THR A 491
SER A 489
TYR A 502
PHE A 487
VAL A 385
 None
 1.35A 1q23L-3vsmA:
undetectable		 1q23L-3vsmA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 11 VAL A 387
THR A 388
GLU A 481
ILE A 445
ALA A 480
 None
 1.32A 2admB-3vsmA:
undetectable		 2admB-3vsmA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 TYR A 288
TYR A 297
ILE A 328
GLY A 281
 None
 1.25A 2du8G-3vsmA:
undetectable		 2du8G-3vsmA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 TYR A 288
TYR A 297
ILE A 328
GLY A 281
 None
 1.35A 2du8J-3vsmA:
undetectable		 2du8J-3vsmA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 LEU A 492
TYR A 380
THR A 374
LEU A 373
 None
 1.06A 2dyrA-3vsmA:
undetectable
2dyrJ-3vsmA:
undetectable		 2dyrA-3vsmA:
21.54
2dyrJ-3vsmA:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 3 ASN A 356
TYR A 350
SER A 333
 None
 0.93A 2gvcB-3vsmA:
undetectable		 2gvcB-3vsmA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 3 ASN A 356
TYR A 350
SER A 333
 None
 0.94A 2gvcE-3vsmA:
undetectable		 2gvcE-3vsmA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_A_3TCA302_1
(DEOXYCYTIDINE KINASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 ILE A 434
LEU A 485
MET A 482
PHE A 479
ALA A 477
 None
 1.34A 2noaA-3vsmA:
undetectable		 2noaA-3vsmA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_A_3TCA302_1
(DEOXYCYTIDINE KINASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 LEU A 485
MET A 482
PHE A 479
ALA A 477
ARG A 411
 None
 1.49A 2noaA-3vsmA:
undetectable		 2noaA-3vsmA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 LEU A 492
TYR A 380
THR A 374
LEU A 373
 None
 1.06A 2zxwA-3vsmA:
undetectable
2zxwJ-3vsmA:
undetectable		 2zxwA-3vsmA:
21.54
2zxwJ-3vsmA:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 7 ILE A 271
TYR A 310
THR A 311
GLY A 241
 None
 1.02A 3gssA-3vsmA:
4.5		 3gssA-3vsmA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 7 ILE A 271
TYR A 310
THR A 311
GLY A 241
 None
 0.98A 3gssB-3vsmA:
4.5		 3gssB-3vsmA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 4 ILE A 267
ARG A 251
ILE A 264
THR A 306
 None
 1.07A 3ia4C-3vsmA:
undetectable		 3ia4C-3vsmA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 ILE A 435
ASN A 504
ILE A 505
SER A 596
VAL A 519
 None
 1.06A 3kpdC-3vsmA:
undetectable		 3kpdC-3vsmA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 9 ASP A 285
ALA A 367
GLY A 386
ILE A 289
ILE A 287
 None
 1.00A 3s45A-3vsmA:
undetectable		 3s45A-3vsmA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 PHE A 357
PHE A 307
ALA A 308
THR A 311
 None
 1.13A 3t3sB-3vsmA:
undetectable		 3t3sB-3vsmA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 ILE A 473
SER A 370
LYS A 371
GLY A 386
 None
 0.80A 3tkdB-3vsmA:
undetectable		 3tkdB-3vsmA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 ILE A 473
SER A 370
LYS A 371
GLY A 386
 None
 0.80A 3tkdA-3vsmA:
undetectable		 3tkdA-3vsmA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 8 ASP A 397
SER A 396
ASN A 401
GLY A 347
 None
 0.96A 4af0A-3vsmA:
undetectable		 4af0A-3vsmA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 GLY A 132
LEU A 130
PHE A 193
VAL A 199
LEU A 200
 None
 1.00A 4fr0A-3vsmA:
undetectable		 4fr0A-3vsmA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 8 GLY A 441
ASN A 440
PRO A 405
ILE A 402
 None
 0.74A 4j4vC-3vsmA:
undetectable		 4j4vC-3vsmA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFJ_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 ALA A 470
LEU A 492
ILE A 669
VAL A 646
THR A 469
 None
 1.04A 4kfjB-3vsmA:
undetectable		 4kfjB-3vsmA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 THR A 306
GLN A  93
THR A 188
HIS A 128
 None
 1.27A 4pfjB-3vsmA:
undetectable		 4pfjB-3vsmA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 3 PRO A 190
MET A 189
TYR A 220
 None
 0.98A 4qa0B-3vsmA:
undetectable		 4qa0B-3vsmA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 3 PRO A 190
MET A 189
TYR A 220
 None
 0.94A 4qa0A-3vsmA:
undetectable		 4qa0A-3vsmA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 3 PRO A 190
MET A 189
TYR A 220
 None
 0.98A 4qa2B-3vsmA:
undetectable		 4qa2B-3vsmA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 8 ILE A 445
LEU A 436
VAL A 507
LEU A 485
 None
 0.82A 4r38A-3vsmA:
undetectable		 4r38A-3vsmA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 5 GLY A 332
GLY A 336
GLU A 335
 None
 0.38A 4z2eA-3vsmA:
undetectable
4z2eD-3vsmA:
undetectable		 4z2eA-3vsmA:
21.28
4z2eD-3vsmA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 ILE A 435
MET A 482
GLY A 433
ILE A 520
GLY A 341
 None
 0.91A 5d4uC-3vsmA:
undetectable		 5d4uC-3vsmA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 ILE A 435
MET A 482
GLY A 433
ILE A 520
GLY A 341
 None
 0.99A 5d4uD-3vsmA:
undetectable		 5d4uD-3vsmA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 10 GLY A 323
LEU A 324
LEU A 300
TYR A 297
TYR A 288
 None
 1.26A 5hwkA-3vsmA:
undetectable		 5hwkA-3vsmA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 10 GLY A 323
LEU A 324
LEU A 300
TYR A 297
TYR A 288
 None
 1.25A 5hwkB-3vsmA:
undetectable		 5hwkB-3vsmA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 12 GLY A 341
VAL A 339
GLY A 386
VAL A 475
ALA A 367
 None
 0.81A 5xv7A-3vsmA:
undetectable		 5xv7A-3vsmA:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 3 HIS A 205
ARG A 159
ILE A 155
 None
 0.77A 6fgdA-3vsmA:
undetectable		 6fgdA-3vsmA:
21.44