SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vsv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 5 HIS A 493
LEU A 486
LEU A 437
GLY A 440
 None
 1.05A 1a4lB-3vsvA:
undetectable		 1a4lB-3vsvA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 PRO A 104
ASP A 125
TRP A 172
TYR A 105
 None
 1.50A 1hpkA-3vsvA:
undetectable		 1hpkA-3vsvA:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 GLN A 523
ARG A 474
TYR A 597
GLY A 431
GLY A 409
 None
 1.30A 1httB-3vsvA:
undetectable		 1httB-3vsvA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 ASP A 562
HIS A 339
ASP A 559
 None
XYP  A 702 (-4.6A)
XYP  A 702 ( 4.0A)
 0.90A 1nw5A-3vsvA:
undetectable		 1nw5A-3vsvA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 GLY A 320
ILE A 354
GLN A 321
VAL A 109
 None
 0.92A 1rs7B-3vsvA:
undetectable		 1rs7B-3vsvA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 10 GLY A 320
ILE A 256
ILE A 264
GLY A 239
ALA A 224
 None
 1.00A 1sh9B-3vsvA:
undetectable		 1sh9B-3vsvA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 GLY A 130
HIS A 257
ASP A 258
TYR A 317
 None
 1.16A 1th6A-3vsvA:
undetectable		 1th6A-3vsvA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.09A 1v55C-3vsvA:
undetectable
1v55N-3vsvA:
undetectable
1v55P-3vsvA:
undetectable		 1v55C-3vsvA:
16.28
1v55N-3vsvA:
21.22
1v55P-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 10 ASP A 318
GLY A 320
ILE A 256
LEU A 240
ALA A 263
 None
 1.07A 1x7pA-3vsvA:
undetectable
1x7pB-3vsvA:
undetectable		 1x7pA-3vsvA:
19.71
1x7pB-3vsvA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 THR A   8
GLU A  69
HIS A   4
 None
 0.56A 1xwfA-3vsvA:
undetectable		 1xwfA-3vsvA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 THR A   8
GLU A  69
HIS A   4
 None
 0.59A 1xwfB-3vsvA:
undetectable		 1xwfB-3vsvA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 THR A   8
GLU A  69
HIS A   4
 None
 0.62A 1xwfC-3vsvA:
undetectable		 1xwfC-3vsvA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 THR A   8
GLU A  69
HIS A   4
 None
 0.62A 1xwfD-3vsvA:
undetectable		 1xwfD-3vsvA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 GLY A 130
HIS A 257
ASP A 258
TYR A 317
 None
 1.14A 2armA-3vsvA:
undetectable		 2armA-3vsvA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 5 PRO A  95
PHE A  99
PHE A  98
ILE A 183
 None
 0.72A 2hjhA-3vsvA:
undetectable		 2hjhA-3vsvA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 ARG A 445
ASN A 398
THR A 156
 None
 0.84A 2q63A-3vsvA:
undetectable		 2q63A-3vsvA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 11 TYR A 411
PHE A 475
ASP A 473
VAL A 402
VAL A 489
 None
 1.30A 2vcdA-3vsvA:
undetectable		 2vcdA-3vsvA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.11A 2y69C-3vsvA:
undetectable
2y69N-3vsvA:
undetectable
2y69P-3vsvA:
undetectable		 2y69C-3vsvA:
16.28
2y69N-3vsvA:
21.22
2y69P-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_C_CTCC1385_0
(TETX2 PROTEIN)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 ASN A 436
PHE A 475
HIS A 582
GLY A 430
MET A 442
 None
 1.46A 2y6rC-3vsvA:
undetectable		 2y6rC-3vsvA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.15A 3ablA-3vsvA:
undetectable
3ablC-3vsvA:
undetectable
3ablP-3vsvA:
undetectable		 3ablA-3vsvA:
21.22
3ablC-3vsvA:
16.28
3ablP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.12A 3ablC-3vsvA:
undetectable
3ablN-3vsvA:
undetectable
3ablP-3vsvA:
undetectable		 3ablC-3vsvA:
16.28
3ablN-3vsvA:
21.22
3ablP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.14A 3abmA-3vsvA:
undetectable
3abmC-3vsvA:
undetectable
3abmP-3vsvA:
undetectable		 3abmA-3vsvA:
21.22
3abmC-3vsvA:
16.28
3abmP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.10A 3asnC-3vsvA:
undetectable
3asnN-3vsvA:
undetectable
3asnP-3vsvA:
undetectable		 3asnC-3vsvA:
16.28
3asnN-3vsvA:
21.22
3asnP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.15A 3asoA-3vsvA:
undetectable
3asoC-3vsvA:
undetectable
3asoP-3vsvA:
undetectable		 3asoA-3vsvA:
21.22
3asoC-3vsvA:
16.28
3asoP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.12A 3asoC-3vsvA:
undetectable
3asoN-3vsvA:
undetectable
3asoP-3vsvA:
undetectable		 3asoC-3vsvA:
16.28
3asoN-3vsvA:
21.22
3asoP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 11 VAL A 365
GLY A 242
TYR A 207
ASN A 244
ILE A 251
 None
 1.45A 3owxA-3vsvA:
undetectable
3owxB-3vsvA:
undetectable		 3owxA-3vsvA:
17.06
3owxB-3vsvA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.13A 3wg7A-3vsvA:
undetectable
3wg7C-3vsvA:
undetectable
3wg7P-3vsvA:
undetectable		 3wg7A-3vsvA:
21.22
3wg7C-3vsvA:
16.28
3wg7P-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.13A 3x2qA-3vsvA:
undetectable
3x2qC-3vsvA:
undetectable
3x2qP-3vsvA:
undetectable		 3x2qA-3vsvA:
21.22
3x2qC-3vsvA:
16.28
3x2qP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.10A 3x2qC-3vsvA:
undetectable
3x2qN-3vsvA:
undetectable
3x2qP-3vsvA:
undetectable		 3x2qC-3vsvA:
16.28
3x2qN-3vsvA:
21.22
3x2qP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 GLU A 588
TYR A 526
SER A 500
 None
 0.78A 4at0A-3vsvA:
undetectable		 4at0A-3vsvA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 GLY A 320
ILE A 354
GLN A 321
VAL A 109
 None
 0.90A 4d39B-3vsvA:
undetectable		 4d39B-3vsvA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 GLU A 252
ILE A 251
ASN A 314
VAL A 365
 None
 1.11A 4ejwB-3vsvA:
undetectable		 4ejwB-3vsvA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 GLU A 291
ASN A 295
GLU A 461
HIS A 455
 None
 1.00A 4ejwB-3vsvA:
undetectable		 4ejwB-3vsvA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 PHE A 294
VAL A 462
GLU A 384
 None
 0.83A 4fvqA-3vsvA:
undetectable		 4fvqA-3vsvA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 ILE A 557
LEU A 555
LYS A 441
GLY A 440
 None
 1.00A 4hc3A-3vsvA:
undetectable		 4hc3A-3vsvA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 GLY A 320
ILE A 354
GLN A 321
VAL A 109
 None
 0.94A 4kcnA-3vsvA:
undetectable		 4kcnA-3vsvA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 GLU A 210
ASP A 214
ILE A 213
ILE A  61
 None
 0.92A 4ndnB-3vsvA:
undetectable		 4ndnB-3vsvA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 PHE A  21
GLU A   2
MET A   1
ILE A  37
 None
 1.42A 4nosA-3vsvA:
undetectable
4nosB-3vsvA:
undetectable		 4nosA-3vsvA:
21.06
4nosB-3vsvA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 TYR A 494
ASN A 495
ILE A 424
ASN A 426
GLY A 440
 None
 1.06A 4obwA-3vsvA:
undetectable		 4obwA-3vsvA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 TYR A 494
ASN A 495
ILE A 424
ASN A 426
GLY A 440
 None
 0.88A 4obwB-3vsvA:
undetectable		 4obwB-3vsvA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 VAL A  89
VAL A 171
TYR A 173
TYR A 184
 None
 0.46A 4pwdC-3vsvA:
undetectable		 4pwdC-3vsvA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 VAL A  89
VAL A 171
TYR A 173
TYR A 184
 None
 0.48A 4q0bA-3vsvA:
undetectable		 4q0bA-3vsvA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 LEU A 628
LEU A 437
ASN A 436
ALA A 531
ILE A 481
 None
 1.06A 4x1iD-3vsvA:
undetectable		 4x1iD-3vsvA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 LYS A 283
PRO A 284
LEU A 290
GLU A 291
 None
 1.04A 4z4cA-3vsvA:
undetectable		 4z4cA-3vsvA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.15A 5b1aA-3vsvA:
undetectable
5b1aC-3vsvA:
undetectable
5b1aP-3vsvA:
undetectable		 5b1aA-3vsvA:
21.22
5b1aC-3vsvA:
16.28
5b1aP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.11A 5b1bA-3vsvA:
undetectable
5b1bC-3vsvA:
undetectable
5b1bP-3vsvA:
undetectable		 5b1bA-3vsvA:
21.22
5b1bC-3vsvA:
16.28
5b1bP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.14A 5b3sA-3vsvA:
undetectable
5b3sC-3vsvA:
undetectable
5b3sP-3vsvA:
undetectable		 5b3sA-3vsvA:
21.22
5b3sC-3vsvA:
16.28
5b3sP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 369
ARG A 389
HIS A 415
THR A 609
 XYP  A 706 (-4.6A)
XYP  A 706 (-3.5A)
None
None
 1.31A 5db5A-3vsvA:
undetectable
5db5B-3vsvA:
undetectable		 5db5A-3vsvA:
21.16
5db5B-3vsvA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 ALA A 531
ASP A 552
PHE A 533
GLY A 482
GLU A 537
 None
 1.19A 5hfjA-3vsvA:
undetectable		 5hfjA-3vsvA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 ALA A 531
ASP A 552
PHE A 533
GLY A 482
GLU A 537
 None
 1.20A 5hfjD-3vsvA:
undetectable		 5hfjD-3vsvA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 ALA A 531
ASP A 552
PHE A 533
GLY A 482
GLU A 537
 None
 1.18A 5hfjG-3vsvA:
undetectable		 5hfjG-3vsvA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.11A 5iy5C-3vsvA:
undetectable
5iy5N-3vsvA:
undetectable
5iy5P-3vsvA:
undetectable		 5iy5C-3vsvA:
16.12
5iy5N-3vsvA:
21.22
5iy5P-3vsvA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 LEU A 142
TYR A 184
THR A 181
ASP A 177
 None
 1.06A 5jq7B-3vsvA:
undetectable		 5jq7B-3vsvA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 ILE A 183
VAL A 197
VAL A 126
TRP A  82
 None
 0.97A 5jwaH-3vsvA:
undetectable		 5jwaH-3vsvA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		5 / 9 ASN A 633
ILE A 417
GLY A 623
ILE A 622
PRO A 553
 None
 1.18A 5kr2A-3vsvA:
undetectable		 5kr2A-3vsvA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 TRP A  82
TYR A 105
ARG A  91
GLN A  93
 None
 1.41A 5tzoC-3vsvA:
undetectable		 5tzoC-3vsvA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.09A 5wauC-3vsvA:
undetectable
5waua-3vsvA:
undetectable
5wauc-3vsvA:
undetectable		 5wauC-3vsvA:
16.28
5waua-3vsvA:
21.22
5wauc-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.10A 5x19A-3vsvA:
undetectable
5x19C-3vsvA:
undetectable
5x19P-3vsvA:
undetectable		 5x19A-3vsvA:
21.22
5x19C-3vsvA:
16.28
5x19P-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.10A 5x1fA-3vsvA:
undetectable
5x1fC-3vsvA:
undetectable
5x1fP-3vsvA:
undetectable		 5x1fA-3vsvA:
21.22
5x1fC-3vsvA:
16.28
5x1fP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.15A 5xdqA-3vsvA:
undetectable
5xdqC-3vsvA:
undetectable
5xdqP-3vsvA:
undetectable		 5xdqA-3vsvA:
21.22
5xdqC-3vsvA:
16.28
5xdqP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.11A 5xdqC-3vsvA:
undetectable
5xdqN-3vsvA:
undetectable
5xdqP-3vsvA:
undetectable		 5xdqC-3vsvA:
16.28
5xdqN-3vsvA:
21.22
5xdqP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.12A 5xdxC-3vsvA:
undetectable
5xdxN-3vsvA:
undetectable
5xdxP-3vsvA:
undetectable		 5xdxC-3vsvA:
16.12
5xdxN-3vsvA:
21.22
5xdxP-3vsvA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.12A 5z84A-3vsvA:
undetectable
5z84C-3vsvA:
undetectable
5z84P-3vsvA:
undetectable		 5z84A-3vsvA:
21.22
5z84C-3vsvA:
16.28
5z84P-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.10A 5z84C-3vsvA:
undetectable
5z84N-3vsvA:
undetectable
5z84P-3vsvA:
undetectable		 5z84C-3vsvA:
16.28
5z84N-3vsvA:
21.22
5z84P-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.15A 5z85A-3vsvA:
undetectable
5z85C-3vsvA:
undetectable
5z85P-3vsvA:
undetectable		 5z85A-3vsvA:
21.22
5z85C-3vsvA:
16.28
5z85P-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.11A 5z85C-3vsvA:
undetectable
5z85N-3vsvA:
undetectable
5z85P-3vsvA:
undetectable		 5z85C-3vsvA:
16.28
5z85N-3vsvA:
21.22
5z85P-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.13A 5z86A-3vsvA:
undetectable
5z86C-3vsvA:
undetectable
5z86P-3vsvA:
undetectable		 5z86A-3vsvA:
21.22
5z86C-3vsvA:
16.28
5z86P-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.10A 5z86C-3vsvA:
undetectable
5z86N-3vsvA:
undetectable
5z86P-3vsvA:
undetectable		 5z86C-3vsvA:
16.28
5z86N-3vsvA:
21.22
5z86P-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.15A 5zcoA-3vsvA:
undetectable
5zcoC-3vsvA:
undetectable
5zcoP-3vsvA:
undetectable		 5zcoA-3vsvA:
21.22
5zcoC-3vsvA:
16.28
5zcoP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.13A 5zcoC-3vsvA:
undetectable
5zcoN-3vsvA:
undetectable
5zcoP-3vsvA:
undetectable		 5zcoC-3vsvA:
16.28
5zcoN-3vsvA:
21.22
5zcoP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.14A 5zcpA-3vsvA:
undetectable
5zcpC-3vsvA:
undetectable
5zcpP-3vsvA:
undetectable		 5zcpA-3vsvA:
21.22
5zcpC-3vsvA:
16.28
5zcpP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 377
HIS A 493
ASP A 401
TYR A 422
 None
 1.12A 5zcpC-3vsvA:
undetectable
5zcpN-3vsvA:
undetectable
5zcpP-3vsvA:
undetectable		 5zcpC-3vsvA:
16.28
5zcpN-3vsvA:
21.22
5zcpP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 HIS A 493
ASP A 401
TYR A 422
LEU A 377
 None
 1.13A 5zcqA-3vsvA:
undetectable
5zcqC-3vsvA:
undetectable
5zcqP-3vsvA:
undetectable		 5zcqA-3vsvA:
21.22
5zcqC-3vsvA:
16.28
5zcqP-3vsvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 3vsv XYLOSIDASE
(Thermoanaerobact
erium
saccharolyticum) 		4 / 7 ASP A 214
GLY A 329
GLY A 307
VAL A 331
 None
 0.66A 6ekzA-3vsvA:
undetectable		 6ekzA-3vsvA:
9.14