SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vte'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I6V_C_RFPC1640_1
(DNA-DIRECTED RNA
POLYMERASE)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 GLN A 145
LEU A 248
ASP A 202
ARG A 231
ILE A 205
 None
 1.21A 1i6vC-3vteA:
undetectable		 1i6vC-3vteA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 11 GLY A 173
PRO A 172
ILE A 246
HIS A 184
VAL A 158
 None
None
None
FAD  A 607 (-3.8A)
None
 1.48A 1tmxA-3vteA:
undetectable		 1tmxA-3vteA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 GLY A 173
PRO A 172
ILE A 246
HIS A 184
VAL A 158
 None
None
None
FAD  A 607 (-3.8A)
None
 1.44A 1tmxB-3vteA:
undetectable		 1tmxB-3vteA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.35A 1v54A-3vteA:
undetectable
1v54C-3vteA:
undetectable		 1v54A-3vteA:
20.62
1v54C-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 1v54N-3vteA:
undetectable
1v54P-3vteA:
undetectable		 1v54N-3vteA:
20.62
1v54P-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.36A 1v55A-3vteA:
undetectable
1v55C-3vteA:
undetectable		 1v55A-3vteA:
20.62
1v55C-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 MET A 264
VAL A 398
LEU A 401
PHE A 293
 None
 1.20A 1x8vA-3vteA:
undetectable		 1x8vA-3vteA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.35A 2dyrA-3vteA:
undetectable
2dyrC-3vteA:
undetectable		 2dyrA-3vteA:
20.62
2dyrC-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.35A 2dyrN-3vteA:
undetectable
2dyrP-3vteA:
undetectable		 2dyrN-3vteA:
20.62
2dyrP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.35A 2dysA-3vteA:
undetectable
2dysC-3vteA:
undetectable		 2dysA-3vteA:
20.62
2dysC-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.38A 2dysN-3vteA:
undetectable
2dysP-3vteA:
undetectable		 2dysN-3vteA:
20.62
2dysP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 2eijA-3vteA:
undetectable
2eijC-3vteA:
undetectable		 2eijA-3vteA:
20.62
2eijC-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 2eijN-3vteA:
undetectable
2eijP-3vteA:
undetectable		 2eijN-3vteA:
20.62
2eijP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.33A 2eikA-3vteA:
undetectable
2eikC-3vteA:
undetectable		 2eikA-3vteA:
20.62
2eikC-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 2eikN-3vteA:
undetectable
2eikP-3vteA:
undetectable		 2eikN-3vteA:
20.62
2eikP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.33A 2eilA-3vteA:
undetectable
2eilC-3vteA:
undetectable		 2eilA-3vteA:
20.62
2eilC-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 2eilN-3vteA:
undetectable
2eilP-3vteA:
undetectable		 2eilN-3vteA:
20.62
2eilP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.33A 2eimA-3vteA:
undetectable
2eimC-3vteA:
undetectable		 2eimA-3vteA:
20.62
2eimC-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.36A 2einA-3vteA:
undetectable
2einC-3vteA:
undetectable		 2einA-3vteA:
20.62
2einC-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.29A 2einN-3vteA:
undetectable
2einP-3vteA:
undetectable		 2einN-3vteA:
20.62
2einP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 GLY A 191
GLY A 189
ASN A 196
ASP A 286
PRO A 418
 None
FAD  A 607 (-3.5A)
None
None
None
 0.93A 2hmyB-3vteA:
undetectable		 2hmyB-3vteA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 ALA A 147
LEU A 248
PHE A 171
VAL A 181
GLY A 182
 None
None
None
None
FAD  A 607 (-3.3A)
 1.09A 2ve3A-3vteA:
undetectable		 2ve3A-3vteA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 2y69A-3vteA:
undetectable
2y69C-3vteA:
undetectable		 2y69A-3vteA:
20.62
2y69C-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.33A 2zxwA-3vteA:
undetectable
2zxwC-3vteA:
undetectable		 2zxwA-3vteA:
20.62
2zxwC-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 3abkA-3vteA:
undetectable
3abkC-3vteA:
undetectable		 3abkA-3vteA:
20.62
3abkC-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.33A 3abkN-3vteA:
undetectable
3abkP-3vteA:
undetectable		 3abkN-3vteA:
20.62
3abkP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 3abmN-3vteA:
undetectable
3abmP-3vteA:
undetectable		 3abmN-3vteA:
20.62
3abmP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 3ag2A-3vteA:
undetectable
3ag2C-3vteA:
undetectable		 3ag2A-3vteA:
20.62
3ag2C-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 3ag2N-3vteA:
undetectable
3ag2P-3vteA:
undetectable		 3ag2N-3vteA:
20.62
3ag2P-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.35A 3ag3A-3vteA:
undetectable
3ag3C-3vteA:
undetectable		 3ag3A-3vteA:
20.62
3ag3C-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.33A 3ag3N-3vteA:
undetectable
3ag3P-3vteA:
undetectable		 3ag3N-3vteA:
20.62
3ag3P-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.35A 3ag4A-3vteA:
undetectable
3ag4C-3vteA:
undetectable		 3ag4A-3vteA:
20.62
3ag4C-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 3asnA-3vteA:
undetectable
3asnC-3vteA:
undetectable		 3asnA-3vteA:
20.62
3asnC-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		3 / 3 MET A 397
VAL A 465
GLU A 402
 None
 0.70A 3c6gA-3vteA:
undetectable		 3c6gA-3vteA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 ALA A 229
GLY A 239
GLY A 234
GLY A 233
ILE A  97
 None
 0.86A 3douA-3vteA:
undetectable		 3douA-3vteA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 GLY A 187
GLU A 236
GLY A 233
ASN A 483
 None
FAD  A 607 (-3.5A)
None
FAD  A 607 (-3.3A)
 0.98A 3e9rA-3vteA:
undetectable		 3e9rA-3vteA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 GLY A 187
GLU A 236
GLY A 233
ASN A 483
 None
FAD  A 607 (-3.5A)
None
FAD  A 607 (-3.3A)
 0.97A 3e9rC-3vteA:
undetectable		 3e9rC-3vteA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 GLU A 224
TRP A 228
LEU A 518
ASN A 514
 None
 1.39A 3k8mB-3vteA:
undetectable		 3k8mB-3vteA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 11 VAL A 158
ILE A 140
SER A 170
LEU A 248
ALA A 147
 None
 1.28A 3kw2A-3vteA:
undetectable		 3kw2A-3vteA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 GLY A 188
ASN A 483
ILE A 431
PHE A 511
LEU A 518
 None
FAD  A 607 (-3.3A)
None
None
None
 1.12A 4kosA-3vteA:
undetectable		 4kosA-3vteA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 GLY A 188
ASN A 483
ILE A 431
PHE A 511
LEU A 518
 None
FAD  A 607 (-3.3A)
None
None
None
 1.13A 4kotA-3vteA:
undetectable		 4kotA-3vteA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 GLY A 188
ASN A 483
ILE A 431
PHE A 511
LEU A 518
 None
FAD  A 607 (-3.3A)
None
None
None
 1.13A 4kovA-3vteA:
undetectable		 4kovA-3vteA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 GLY A 191
GLY A 173
LEU A 155
TYR A 481
TYR A 484
 None
None
None
FAD  A 607 (-4.4A)
FAD  A 607 (-4.7A)
 1.02A 4lg1A-3vteA:
undetectable		 4lg1A-3vteA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 GLY A 191
GLY A 173
LEU A 155
TYR A 481
TYR A 484
 None
None
None
FAD  A 607 (-4.4A)
FAD  A 607 (-4.7A)
 1.00A 4lg1B-3vteA:
undetectable		 4lg1B-3vteA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 GLY A 191
GLY A 173
LEU A 155
TYR A 481
TYR A 484
 None
None
None
FAD  A 607 (-4.4A)
FAD  A 607 (-4.7A)
 1.02A 4lg1C-3vteA:
undetectable		 4lg1C-3vteA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 5 ILE A 348
HIS A 184
TYR A 197
VAL A 249
 None
FAD  A 607 (-3.8A)
None
None
 1.20A 4s0vA-3vteA:
undetectable		 4s0vA-3vteA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		3 / 3 ALA A 243
TRP A 148
VAL A 149
 None
 0.36A 4w9nC-3vteA:
undetectable		 4w9nC-3vteA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		3 / 3 ASP A  57
ARG A 110
ARG A 133
 None
 0.79A 4x5iA-3vteA:
undetectable		 4x5iA-3vteA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		3 / 3 ASP A 341
LEU A 335
GLY A 336
 None
 0.52A 4xmfA-3vteA:
undetectable		 4xmfA-3vteA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 ILE A 431
GLY A 188
ALA A 201
ASP A 202
TYR A 387
 None
 1.25A 4xt8A-3vteA:
undetectable		 4xt8A-3vteA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 LEU A 482
GLY A 183
GLY A 182
ILE A 241
 None
FAD  A 607 (-3.1A)
FAD  A 607 (-3.3A)
FAD  A 607 (-4.0A)
 0.74A 4yjiA-3vteA:
undetectable		 4yjiA-3vteA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 5 ARG A 110
GLY A 152
GLU A 150
SER A  66
 None
 0.87A 4z3oA-3vteA:
3.6
4z3oB-3vteA:
3.5		 4z3oA-3vteA:
22.51
4z3oB-3vteA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 ARG A 110
GLY A 152
GLU A 150
SER A  66
 None
 0.84A 4z53A-3vteA:
3.6
4z53B-3vteA:
3.3		 4z53A-3vteA:
22.51
4z53B-3vteA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.32A 5b1aN-3vteA:
undetectable
5b1aP-3vteA:
undetectable		 5b1aN-3vteA:
20.62
5b1aP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.32A 5b1bN-3vteA:
undetectable
5b1bP-3vteA:
undetectable		 5b1bN-3vteA:
20.62
5b1bP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.31A 5b3sN-3vteA:
undetectable
5b3sP-3vteA:
undetectable		 5b3sN-3vteA:
20.62
5b3sP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 ARG A 110
SER A  66
GLY A 152
GLU A 150
 None
 0.85A 5cdqA-3vteA:
3.1
5cdqC-3vteA:
3.4
5cdqD-3vteA:
undetectable		 5cdqA-3vteA:
20.92
5cdqC-3vteA:
20.92
5cdqD-3vteA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 ALA A 380
ASP A 408
GLY A 412
THR A 295
SER A 382
 None
 1.24A 5hfjB-3vteA:
undetectable		 5hfjB-3vteA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 ALA A 380
ASP A 408
GLY A 412
THR A 295
SER A 382
 None
 1.22A 5hfjG-3vteA:
undetectable		 5hfjG-3vteA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.34A 5iy5A-3vteA:
undetectable
5iy5C-3vteA:
undetectable		 5iy5A-3vteA:
20.62
5iy5C-3vteA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 7 GLY A 183
GLY A 187
PHE A 433
GLY A 188
LEU A 199
 FAD  A 607 (-3.1A)
None
None
None
None
 1.27A 5izjB-3vteA:
undetectable		 5izjB-3vteA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		5 / 12 GLY A 191
VAL A 249
ILE A 246
GLY A 188
GLY A 189
 None
None
None
None
FAD  A 607 (-3.5A)
 0.81A 5koxA-3vteA:
undetectable		 5koxA-3vteA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 THR A 291
PHE A 273
GLN A 277
MET A 397
 None
 1.25A 5u6mA-3vteA:
undetectable		 5u6mA-3vteA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.27A 5x19N-3vteA:
undetectable
5x19P-3vteA:
undetectable		 5x19N-3vteA:
20.62
5x19P-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.30A 5x1bN-3vteA:
undetectable
5x1bP-3vteA:
undetectable		 5x1bN-3vteA:
20.62
5x1bP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.29A 5x1fN-3vteA:
undetectable
5x1fP-3vteA:
undetectable		 5x1fN-3vteA:
20.62
5x1fP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		3 / 3 ARG A 195
GLY A 421
GLU A 424
 None
 0.58A 6fgdA-3vteA:
undetectable		 6fgdA-3vteA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 6 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.32A 6nknA-3vteA:
undetectable
6nknC-3vteA:
undetectable		 6nknA-3vteA:
20.62
6nknC-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.22A 6nmfN-3vteA:
undetectable
6nmfP-3vteA:
undetectable		 6nmfN-3vteA:
20.62
6nmfP-3vteA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vte TETRAHYDROCANNABINOL
IC ACID SYNTHASE
(Cannabis
sativa) 		4 / 7 HIS A 318
ASP A 349
THR A 350
TYR A 354
 None
 1.25A 6nmpN-3vteA:
undetectable
6nmpP-3vteA:
undetectable		 6nmpN-3vteA:
20.62
6nmpP-3vteA:
16.73