SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vti'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 8 PHE C 118
GLU C 115
ILE C 157
LEU C  79
 None
 0.89A 1hmyA-3vtiC:
undetectable		 1hmyA-3vtiC:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 7 MET C 198
GLU C 202
LEU C 204
MET C 277
 None
 0.86A 1linA-3vtiC:
undetectable		 1linA-3vtiC:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 4 VAL C 242
LEU C 224
ILE C 221
LEU C 217
 None
 1.04A 2byoA-3vtiC:
undetectable		 2byoA-3vtiC:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 5 LEU C 284
ALA C 196
ILE C 210
SER C 199
 None
 1.01A 2othA-3vtiC:
undetectable		 2othA-3vtiC:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 9 LEU C 234
ILE C 257
GLY C 319
ILE C 317
VAL C 290
 None
 1.17A 2r5qA-3vtiC:
undetectable		 2r5qA-3vtiC:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 9 LEU C 234
ILE C 257
GLY C 319
ILE C 317
VAL C 290
 None
 1.17A 2r5qC-3vtiC:
undetectable		 2r5qC-3vtiC:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 12 ILE C 175
GLU C 248
SER C 187
ALA C 315
LEU C 224
 None
 1.14A 2xkwB-3vtiC:
undetectable		 2xkwB-3vtiC:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 5 ASN C 322
THR C 331
SER C 336
ARG C 337
 None
 1.22A 3hlwB-3vtiC:
undetectable		 3hlwB-3vtiC:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 10 ASP C 213
GLY C 288
GLY C 241
VAL C 242
VAL C 270
 None
 1.03A 3oxwA-3vtiC:
undetectable		 3oxwA-3vtiC:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 10 ASP C 213
GLY C 288
GLY C 241
VAL C 242
VAL C 270
 None
 0.99A 3oxwC-3vtiC:
undetectable		 3oxwC-3vtiC:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 6 GLY C  83
VAL C 214
HIS C 193
SER C 212
 None
 1.07A 3tj7A-3vtiC:
undetectable
3tj7B-3vtiC:
undetectable		 3tj7A-3vtiC:
22.08
3tj7B-3vtiC:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 6 GLY C  83
VAL C 214
HIS C 193
SER C 212
 None
 1.07A 3tj7C-3vtiC:
undetectable
3tj7D-3vtiC:
undetectable		 3tj7C-3vtiC:
22.08
3tj7D-3vtiC:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 6 VAL C 214
HIS C 193
SER C 212
GLY C  83
 None
 1.09A 3tj7C-3vtiC:
undetectable
3tj7D-3vtiC:
undetectable		 3tj7C-3vtiC:
22.08
3tj7D-3vtiC:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 7 PRO C 237
LEU C 217
LEU C 220
ILE C 186
 None
 0.93A 3u5jA-3vtiC:
undetectable		 3u5jA-3vtiC:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 8 PRO C 237
LEU C 217
LEU C 220
ILE C 186
 None
 0.90A 3u5kA-3vtiC:
undetectable		 3u5kA-3vtiC:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 12 VAL C 245
SER C 253
ILE C 186
ILE C 231
LEU C 224
 None
 1.25A 3w67D-3vtiC:
undetectable		 3w67D-3vtiC:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 8 LEU C 220
GLY C 219
GLU C 136
ALA C 133
 None
 0.73A 4rjdA-3vtiC:
undetectable
4rjdB-3vtiC:
undetectable		 4rjdA-3vtiC:
13.40
4rjdB-3vtiC:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		3 / 3 SER C  73
ALA C  90
VAL C  91
 None
 0.59A 4x1iA-3vtiC:
undetectable		 4x1iA-3vtiC:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		3 / 3 LYS C 289
ILE C 186
ILE C 318
 None
 0.70A 4y0qA-3vtiC:
undetectable		 4y0qA-3vtiC:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 12 THR C  68
SER C 162
GLY C 163
ALA C  98
THR C  94
 None
 1.22A 5l5zV-3vtiC:
undetectable
5l5zb-3vtiC:
undetectable		 5l5zV-3vtiC:
22.40
5l5zb-3vtiC:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 12 THR C  68
SER C 162
GLY C 163
ALA C  98
THR C  94
 None
 1.22A 5l5zH-3vtiC:
undetectable
5l5zN-3vtiC:
undetectable		 5l5zH-3vtiC:
22.40
5l5zN-3vtiC:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 12 THR C  68
SER C 162
GLY C 163
ALA C  98
THR C  94
 None
 1.18A 5lf3b-3vtiC:
undetectable		 5lf3b-3vtiC:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 12 THR C  68
SER C 162
GLY C 163
ALA C  98
THR C  94
 None
 1.19A 5lf3N-3vtiC:
undetectable		 5lf3N-3vtiC:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 12 THR C  68
SER C 162
GLY C 163
ALA C  98
THR C  94
 None
 1.20A 5lf7V-3vtiC:
undetectable
5lf7b-3vtiC:
undetectable		 5lf7V-3vtiC:
21.82
5lf7b-3vtiC:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 12 THR C  68
SER C 162
GLY C 163
ALA C  98
THR C  94
 None
 1.20A 5lf7H-3vtiC:
undetectable
5lf7N-3vtiC:
undetectable		 5lf7H-3vtiC:
21.82
5lf7N-3vtiC:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		4 / 7 VAL C 149
PRO C  78
PHE C 118
LEU C  79
 None
 1.21A 6aycA-3vtiC:
undetectable		 6aycA-3vtiC:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3vti HYDROGENASE
MATURATION FACTOR
(Caldanaerobacter
subterraneus) 		5 / 12 LEU C 123
PRO C 119
ILE C 126
ILE C 114
ILE C 157
 None
 0.97A 6emuA-3vtiC:
undetectable		 6emuA-3vtiC:
21.85