SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vu0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G1U_B_ADNB438_2 (ADENOSYLHOMOCYSTEINA SE)	3vu0	PUTATIVE UNCHARACTERIZED PROTEIN (Archaeoglobus fulgidus)	3 / 3	THR A 435 GLU A 524 HIS A 568	None	0.63A	3g1uB-3vu0A: undetectable	3g1uB-3vu0A: 17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HWK_B_SFYB806_0 (SEPIAPTERIN REDUCTASE)	3vu0	PUTATIVE UNCHARACTERIZED PROTEIN (Archaeoglobus fulgidus)	5 / 11	LEU A 442 SER A 467 TRP A 438 MET A 445 ALA A 441	None	1.42A	4hwkB-3vu0A: undetectable	4hwkB-3vu0A: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HWK_C_SFYC804_0 (SEPIAPTERIN REDUCTASE)	3vu0	PUTATIVE UNCHARACTERIZED PROTEIN (Archaeoglobus fulgidus)	5 / 12	LEU A 442 SER A 467 TRP A 438 MET A 445 ALA A 441	None	1.43A	4hwkC-3vu0A: undetectable	4hwkC-3vu0A: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YDQ_B_HFGB802_1 (PROLINE--TRNA LIGASE)	3vu0	PUTATIVE UNCHARACTERIZED PROTEIN (Archaeoglobus fulgidus)	3 / 3	GLU A 505 THR A 576 HIS A 577	None	0.84A	4ydqB-3vu0A: undetectable	4ydqB-3vu0A: 16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKQ_A_JMSA602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	3vu0	PUTATIVE UNCHARACTERIZED PROTEIN (Archaeoglobus fulgidus)	3 / 3	VAL A 587 SER A 467 MET A 563	None	0.90A	5ikqA-3vu0A: undetectable	5ikqA-3vu0A: 14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JVZ_B_FLPB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3vu0	PUTATIVE UNCHARACTERIZED PROTEIN (Archaeoglobus fulgidus)	5 / 12	LEU A 466 SER A 467 LEU A 525 GLY A 491 ALA A 492	None	1.02A	5jvzB-3vu0A: undetectable	5jvzB-3vu0A: 15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_A_ACRA608_0 (ALPHA-AMYLASE)	3vu0	PUTATIVE UNCHARACTERIZED PROTEIN (Archaeoglobus fulgidus)	4 / 6	PHE A 536 THR A 500 GLN A 502 TYR A 545	None	1.02A	6ag0A-3vu0A: undetectable	6ag0A-3vu0A: 18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_C_ACRC606_0 (ALPHA-AMYLASE)	3vu0	PUTATIVE UNCHARACTERIZED PROTEIN (Archaeoglobus fulgidus)	4 / 6	PHE A 536 THR A 500 GLN A 502 TYR A 545	None	1.06A	6ag0C-3vu0A: undetectable	6ag0C-3vu0A: 18.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3G1U_B_ADNB438_2","ADENOSYLHOMOCYSTEINASE","3vu0","PUTATIVE UNCHARACTERIZED PROTEIN","Archaeoglobus fulgidus",3,"THR A 435;GLU A 524;HIS A 568","None","0.63A","3g1uB-3vu0A:undetectable","3g1uB-3vu0A:17.51"],["4HWK_B_SFYB806_0","SEPIAPTERIN REDUCTASE","3vu0","PUTATIVE UNCHARACTERIZED PROTEIN","Archaeoglobus fulgidus",5,"LEU A 442;SER A 467;TRP A 438;MET A 445;ALA A 441","None","1.42A","4hwkB-3vu0A:undetectable","4hwkB-3vu0A:18.15"],["4HWK_C_SFYC804_0","SEPIAPTERIN REDUCTASE","3vu0","PUTATIVE UNCHARACTERIZED PROTEIN","Archaeoglobus fulgidus",5,"LEU A 442;SER A 467;TRP A 438;MET A 445;ALA A 441","None","1.43A","4hwkC-3vu0A:undetectable","4hwkC-3vu0A:18.15"],["4YDQ_B_HFGB802_1","PROLINE--TRNA LIGASE","3vu0","PUTATIVE UNCHARACTERIZED PROTEIN","Archaeoglobus fulgidus",3,"GLU A 505;THR A 576;HIS A 577","None","0.84A","4ydqB-3vu0A:undetectable","4ydqB-3vu0A:16.08"],["5IKQ_A_JMSA602_2","PROSTAGLANDIN G\/H SYNTHASE 2","3vu0","PUTATIVE UNCHARACTERIZED PROTEIN","Archaeoglobus fulgidus",3,"VAL A 587;SER A 467;MET A 563","None","0.90A","5ikqA-3vu0A:undetectable","5ikqA-3vu0A:14.53"],["5JVZ_B_FLPB601_1","PROSTAGLANDIN G\/H SYNTHASE 2","3vu0","PUTATIVE UNCHARACTERIZED PROTEIN","Archaeoglobus fulgidus",5,"LEU A 466;SER A 467;LEU A 525;GLY A 491;ALA A 492","None","1.02A","5jvzB-3vu0A:undetectable","5jvzB-3vu0A:15.31"],["6AG0_A_ACRA608_0","ALPHA-AMYLASE","3vu0","PUTATIVE UNCHARACTERIZED PROTEIN","Archaeoglobus fulgidus",4,"PHE A 536;THR A 500;GLN A 502;TYR A 545","None","1.02A","6ag0A-3vu0A:undetectable","6ag0A-3vu0A:18.90"],["6AG0_C_ACRC606_0","ALPHA-AMYLASE","3vu0","PUTATIVE UNCHARACTERIZED PROTEIN","Archaeoglobus fulgidus",4,"PHE A 536;THR A 500;GLN A 502;TYR A 545","None","1.06A","6ag0C-3vu0A:undetectable","6ag0C-3vu0A:18.90"]]