SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vu1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		5 / 10 TYR A 961
ILE A 820
ALA A 822
ILE A 763
ILE A 735
 None
 1.22A 2dm6A-3vu1A:
undetectable
2dm6B-3vu1A:
undetectable		 2dm6A-3vu1A:
22.14
2dm6B-3vu1A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 5 PHE A 567
PHE A 716
LEU A 712
PHE A 708
 None
 1.36A 3abmP-3vu1A:
undetectable
3abmW-3vu1A:
undetectable		 3abmP-3vu1A:
17.84
3abmW-3vu1A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 5 PHE A 567
PHE A 716
LEU A 712
PHE A 708
 None
 1.34A 3ag3C-3vu1A:
undetectable
3ag3J-3vu1A:
undetectable		 3ag3C-3vu1A:
17.84
3ag3J-3vu1A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		5 / 12 ASP A 769
LEU A 821
ILE A 763
PHE A 730
ASP A 558
 None
 1.00A 3ko0G-3vu1A:
undetectable
3ko0H-3vu1A:
undetectable
3ko0I-3vu1A:
undetectable
3ko0J-3vu1A:
undetectable		 3ko0G-3vu1A:
11.06
3ko0H-3vu1A:
11.06
3ko0I-3vu1A:
11.06
3ko0J-3vu1A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		5 / 9 ALA A 620
ILE A 639
ILE A 605
ILE A 624
ILE A 622
 None
 0.97A 3s43A-3vu1A:
undetectable		 3s43A-3vu1A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		5 / 9 ALA A 620
ILE A 639
ILE A 605
ILE A 624
ILE A 622
 None
 1.00A 3s45A-3vu1A:
undetectable		 3s45A-3vu1A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		5 / 11 ALA A 620
ILE A 639
ILE A 605
ILE A 624
ILE A 622
 None
 0.96A 3s53B-3vu1A:
undetectable		 3s53B-3vu1A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 5 TRP A 513
GLY A 584
ALA A 549
PHE A 567
 None
 1.24A 3wqwA-3vu1A:
undetectable		 3wqwA-3vu1A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 8 GLN A 823
ILE A 770
GLY A 767
ASN A 715
 None
 0.92A 4fgjA-3vu1A:
undetectable
4fgjB-3vu1A:
undetectable		 4fgjA-3vu1A:
17.91
4fgjB-3vu1A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 5 PHE A 733
TYR A 961
THR A 774
ILE A 770
 None
 0.98A 4jx1E-3vu1A:
undetectable		 4jx1E-3vu1A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		5 / 10 GLY A 828
THR A 831
VAL A 861
LEU A 524
SER A 505
 None
 1.35A 4yb6C-3vu1A:
undetectable
4yb6F-3vu1A:
undetectable		 4yb6C-3vu1A:
20.65
4yb6F-3vu1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		5 / 10 LEU A 524
SER A 505
GLY A 828
THR A 831
VAL A 861
 None
 1.34A 4yb6D-3vu1A:
undetectable
4yb6E-3vu1A:
undetectable		 4yb6D-3vu1A:
20.65
4yb6E-3vu1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 7 GLU A 710
TYR A 736
GLU A 748
TYR A 762
 None
 1.11A 4zz8A-3vu1A:
0.4		 4zz8A-3vu1A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		5 / 10 PRO A 953
LEU A 830
VAL A 861
ILE A 909
LEU A 911
 None
 1.07A 5ienB-3vu1A:
undetectable		 5ienB-3vu1A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 4 ASN A 798
ILE A 735
TYR A 736
PHE A 716
 None
 1.19A 5igvA-3vu1A:
undetectable		 5igvA-3vu1A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		5 / 12 ASP A 551
GLY A 552
ASN A 553
ALA A 765
ASN A 715
 None
None
None
CA  A1001 (-4.8A)
None
 1.29A 5kc4E-3vu1A:
undetectable		 5kc4E-3vu1A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 6 LEU A 871
ILE A 876
MET A 897
TRP A 562
 None
 1.41A 5ljeA-3vu1A:
undetectable		 5ljeA-3vu1A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 6 LEU A 648
SER A 645
ARG A 634
GLY A 660
 None
 0.92A 5o4yF-3vu1A:
undetectable		 5o4yF-3vu1A:
5.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 5 PHE A 567
PHE A 716
LEU A 712
PHE A 708
 None
 1.32A 5wauC-3vu1A:
undetectable
5wauJ-3vu1A:
undetectable		 5wauC-3vu1A:
17.84
5wauJ-3vu1A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 5 PHE A 567
PHE A 716
LEU A 712
PHE A 708
 None
 1.32A 5wauc-3vu1A:
undetectable
5wauj-3vu1A:
undetectable		 5wauc-3vu1A:
17.84
5wauj-3vu1A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 5 PHE A 567
PHE A 716
LEU A 712
PHE A 708
 None
 1.31A 5xdqC-3vu1A:
undetectable
5xdqJ-3vu1A:
undetectable		 5xdqC-3vu1A:
17.84
5xdqJ-3vu1A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		4 / 5 PHE A 567
PHE A 716
LEU A 712
PHE A 708
 None
 1.32A 5xdqP-3vu1A:
undetectable
5xdqW-3vu1A:
undetectable		 5xdqP-3vu1A:
17.84
5xdqW-3vu1A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 3vu1 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0242
(Pyrococcus
horikoshii) 		5 / 9 LEU A 800
ARG A 768
VAL A 557
SER A 555
ASP A 558
 None
CL  A1002 (-3.4A)
None
None
None
 1.08A 6c2mB-3vu1A:
0.0		 6c2mB-3vu1A:
9.07