SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vu7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 3vu7 DNA REPAIR PROTEIN
REV1
(Homo
sapiens) 		3 / 3 TYR H1212
ARG H1173
LYS H1169
 None
 1.23A 4wq5B-3vu7H:
undetectable		 4wq5B-3vu7H:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 3vu7 DNA REPAIR PROTEIN
REV1
(Homo
sapiens) 		4 / 4 VAL H1239
LEU H1240
LEU H1248
ASP H1207
 None
 1.42A 5xv7A-3vu7H:
undetectable		 5xv7A-3vu7H:
22.81