SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vu9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 TYR B 115
LEU B  20
THR B  43
ILE B  69
LEU B  37
 None
 1.08A 1tw4B-3vu9B:
undetectable		 1tw4B-3vu9B:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 LEU B 163
LEU B 143
MET B 122
SER B 126
 None
 1.06A 1wrlE-3vu9B:
undetectable
1wrlF-3vu9B:
undetectable		 1wrlE-3vu9B:
16.27
1wrlF-3vu9B:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 5 ASP B 141
LEU B 144
LYS B 145
ARG B 140
 None
 1.37A 2gj5A-3vu9B:
undetectable		 2gj5A-3vu9B:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 6 ASP B  41
ILE B 116
LEU B  80
GLU B 120
 None
 1.04A 2ya7A-3vu9B:
undetectable		 2ya7A-3vu9B:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 6 ASP B  41
ILE B 116
LEU B  80
GLU B 120
 None
 1.04A 2ya7B-3vu9B:
undetectable		 2ya7B-3vu9B:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 6 ASP B  41
ILE B 116
LEU B  80
GLU B 120
 None
 1.05A 2ya7D-3vu9B:
undetectable		 2ya7D-3vu9B:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU B  80
THR B 142
MET B 122
LEU B 199
ILE B 203
 None
 1.46A 2ydoA-3vu9B:
undetectable		 2ydoA-3vu9B:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE B   9
THR B 142
THR B 161
ILE B  11
ILE B 203
 None
 1.25A 2yzqA-3vu9B:
undetectable		 2yzqA-3vu9B:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 4 ILE B 112
PHE B  38
ILE B  90
THR B 161
 None
 1.03A 3ia4A-3vu9B:
undetectable		 3ia4A-3vu9B:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 LEU B 139
ILE B 159
THR B 161
MET B 149
 None
 1.13A 5ljcA-3vu9B:
undetectable		 5ljcA-3vu9B:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 CYH B  74
MET B 122
ASN B 125
 None
 0.98A 5qh8A-3vu9B:
undetectable		 5qh8A-3vu9B:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 LEU B 162
ILE B   9
THR B  10
TYR B   3
 None
None
EDO  B 301 ( 4.1A)
None
 0.93A 5zsfA-3vu9B:
undetectable
5zsfB-3vu9B:
undetectable		 5zsfA-3vu9B:
17.65
5zsfB-3vu9B:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 6 ASP B  41
TYR B 115
GLU B 164
GLU B 168
 None
 1.49A 6mn5C-3vu9B:
undetectable		 6mn5C-3vu9B:
18.10