SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vuq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3vuq TRANSCRIPTIONAL
REGULATOR (TETR/ACRR
FAMILY)
(Thermus
thermophilus) 		4 / 8 ARG A 138
THR A 155
ALA A 156
ALA A 157
 None
 0.57A 2ej3A-3vuqA:
undetectable		 2ej3A-3vuqA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 3vuq TRANSCRIPTIONAL
REGULATOR (TETR/ACRR
FAMILY)
(Thermus
thermophilus) 		4 / 7 ARG A 147
LEU A 150
VAL A 158
THR A 155
 None
 1.01A 5e4dA-3vuqA:
undetectable
5e4dB-3vuqA:
undetectable		 5e4dA-3vuqA:
18.52
5e4dB-3vuqA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3vuq TRANSCRIPTIONAL
REGULATOR (TETR/ACRR
FAMILY)
(Thermus
thermophilus) 		5 / 12 ILE A 159
ALA A 160
PHE A  86
GLY A 140
LEU A 130
 None
 0.87A 5i71A-3vuqA:
undetectable		 5i71A-3vuqA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3vuq TRANSCRIPTIONAL
REGULATOR (TETR/ACRR
FAMILY)
(Thermus
thermophilus) 		5 / 12 ILE A 159
ALA A 160
PHE A  86
GLY A 140
LEU A 130
 None
 0.90A 5i73A-3vuqA:
2.4		 5i73A-3vuqA:
13.84