SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_B_DOLB301_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 3vut DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 4
(Homo
sapiens) 		5 / 12 ILE A 250
MET A 153
VAL A 286
TYR A 358
ASP A 289
 None
 1.14A 1mrlB-3vutA:
undetectable
1mrlC-3vutA:
undetectable		 1mrlB-3vutA:
19.94
1mrlC-3vutA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 3vut DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 4
(Homo
sapiens) 		4 / 8 ILE A 367
TYR A 358
LEU A 293
LEU A 297
 None
 0.88A 2w98B-3vutA:
undetectable		 2w98B-3vutA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 3vut DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 4
(Homo
sapiens) 		4 / 7 GLY A 294
ILE A 230
THR A 212
LEU A 297
 None
 0.95A 2xrhA-3vutA:
undetectable		 2xrhA-3vutA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 3vut DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 4
(Homo
sapiens) 		4 / 7 ILE A 341
PHE A 366
LYS A 207
GLY A 206
 None
 1.05A 3sj0X-3vutA:
undetectable		 3sj0X-3vutA:
13.36