SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vuu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ALA A 306
ARG A 208
ILE A 215
LEU A 213
ILE A 234
 None
 1.27A 1d1gA-3vuuA:
undetectable		 1d1gA-3vuuA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		5 / 11 VAL A 317
ASN A 313
GLU A 231
GLU A 312
ILE A 271
 None
 1.20A 1t6zA-3vuuA:
undetectable		 1t6zA-3vuuA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		3 / 3 LYS A 417
ASP A 275
ASN A 199
 None
 1.15A 2bm9A-3vuuA:
undetectable		 2bm9A-3vuuA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 8 TYR A 337
ASN A 339
PRO A 344
PHE A 346
 None
 1.45A 3bjwD-3vuuA:
undetectable		 3bjwD-3vuuA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		3 / 3 LYS A 193
ILE A 215
PHE A 220
 None
 0.59A 3j7zS-3vuuA:
0.8
3j7za-3vuuA:
undetectable		 3j7zS-3vuuA:
17.45
3j7za-3vuuA:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		3 / 3 LYS A 302
PRO A 303
LEU A 293
 None
 0.61A 3tpxE-3vuuA:
undetectable		 3tpxE-3vuuA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		3 / 3 ARG A 348
ARG A 272
ASP A 275
 None
 0.62A 3wipG-3vuuA:
undetectable
3wipH-3vuuA:
undetectable		 3wipG-3vuuA:
18.63
3wipH-3vuuA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		3 / 3 TYR A 237
ASP A 219
ASP A 229
 None
 0.63A 4a6eA-3vuuA:
undetectable		 4a6eA-3vuuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 7 LEU A 203
VAL A 204
PRO A 206
LYS A 406
 None
 0.64A 4lb2A-3vuuA:
undetectable		 4lb2A-3vuuA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 6 ARG A 272
ARG A 348
ASP A 274
ASP A 266
 None
 1.41A 4xqeA-3vuuA:
undetectable		 4xqeA-3vuuA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 6 ARG A 348
ARG A 272
ASP A 266
ASP A 274
 None
 1.39A 4xqeA-3vuuA:
undetectable		 4xqeA-3vuuA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 6 ARG A 272
ARG A 348
ASP A 274
ASP A 266
 None
 1.39A 4xqeB-3vuuA:
undetectable		 4xqeB-3vuuA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		5 / 10 TYR A 288
ILE A 215
ILE A 271
ILE A 270
ILE A 267
 None
 0.91A 5murE-3vuuA:
3.2		 5murE-3vuuA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 6 ARG A 351
GLY A 354
THR A 355
GLU A 443
 None
 1.09A 5ny7A-3vuuA:
undetectable		 5ny7A-3vuuA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 7 THR A 222
ILE A 215
THR A 216
PHE A 233
 None
 0.98A 5zsfA-3vuuA:
undetectable
5zsfB-3vuuA:
undetectable		 5zsfA-3vuuA:
12.67
5zsfB-3vuuA:
12.67