SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vuv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ALA A 306
ARG A 208
ILE A 215
LEU A 213
ILE A 234
 None
 1.25A 1d1gA-3vuvA:
undetectable		 1d1gA-3vuvA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		5 / 11 VAL A 317
ASN A 313
GLU A 231
GLU A 312
ILE A 271
 None
 1.26A 1t6zA-3vuvA:
undetectable		 1t6zA-3vuvA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		5 / 11 VAL A 317
ASN A 313
GLU A 231
GLU A 312
ILE A 271
 None
 1.27A 1t6zB-3vuvA:
undetectable		 1t6zB-3vuvA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 6 ARG A 314
TRP A 318
GLU A 319
ALA A 238
 None
None
ZN  A 503 (-2.9A)
None
 1.43A 2ejfB-3vuvA:
undetectable		 2ejfB-3vuvA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		3 / 3 LYS A 193
ILE A 215
PHE A 220
 None
 0.65A 3j7zS-3vuvA:
0.8
3j7za-3vuvA:
undetectable		 3j7zS-3vuvA:
15.66
3j7za-3vuvA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		3 / 3 LYS A 302
PRO A 303
LEU A 293
 None
 0.73A 3tpxE-3vuvA:
undetectable		 3tpxE-3vuvA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		3 / 3 ARG A 348
ARG A 272
ASP A 275
 None
 0.63A 3wipG-3vuvA:
undetectable
3wipH-3vuvA:
undetectable		 3wipG-3vuvA:
18.05
3wipH-3vuvA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 5 THR A 430
LEU A 431
GLU A 439
LYS A 440
 None
 0.99A 4a3pA-3vuvA:
undetectable		 4a3pA-3vuvA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		3 / 3 TYR A 237
ASP A 219
ASP A 229
 None
 0.68A 4a6eA-3vuvA:
undetectable		 4a6eA-3vuvA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 6 ARG A 272
ARG A 348
ASP A 274
ASP A 266
 None
 1.42A 4xqeA-3vuvA:
undetectable		 4xqeA-3vuvA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 6 ARG A 272
ARG A 348
ASP A 274
ASP A 266
 None
 1.41A 4xqeB-3vuvA:
undetectable		 4xqeB-3vuvA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE
(Plasmodium
falciparum) 		4 / 7 THR A 222
ILE A 215
THR A 216
PHE A 233
 None
 1.02A 5zsfA-3vuvA:
undetectable
5zsfB-3vuvA:
undetectable		 5zsfA-3vuvA:
13.47
5zsfB-3vuvA:
13.47