SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vv1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		4 / 8 PHE A  61
ILE A 109
LEU A  98
GLU A  99
 None
 0.89A 1eupA-3vv1A:
undetectable		 1eupA-3vv1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		4 / 7 PHE A 100
VAL A  70
VAL A 111
ILE A 109
 None
 0.98A 1p7rA-3vv1A:
undetectable		 1p7rA-3vv1A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		4 / 6 LEU A  51
LEU A  59
ILE A 131
ARG A  52
 None
 1.06A 2rlfA-3vv1A:
undetectable
2rlfB-3vv1A:
undetectable		 2rlfA-3vv1A:
16.55
2rlfB-3vv1A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		4 / 6 LEU A  51
LEU A  59
ILE A 131
ARG A  52
 None
 1.00A 2rlfC-3vv1A:
undetectable
2rlfD-3vv1A:
undetectable		 2rlfC-3vv1A:
16.55
2rlfD-3vv1A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		4 / 8 HIS A 115
ASP A 118
SER A 108
ILE A 106
 None
 1.12A 2xadB-3vv1A:
undetectable		 2xadB-3vv1A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		4 / 8 HIS A 115
ASP A 118
SER A 108
ILE A 106
 None
 1.12A 2xadD-3vv1A:
undetectable		 2xadD-3vv1A:
20.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_A_1GNA998_1
(GALECTIN-7)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		6 / 6 HIS A  60
ASN A  62
ARG A  64
ASN A  73
TRP A  80
GLU A  83
 GAL  A 201 (-3.8A)
GAL  A 201 (-3.9A)
FUC  A 202 (-2.7A)
GAL  A 201 (-3.8A)
GAL  A 201 ( 3.8A)
FUC  A 202 (-2.7A)
 0.17A 3galA-3vv1A:
21.1		 3galA-3vv1A:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_B_1GNB999_1
(GALECTIN-7)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		6 / 6 HIS A  60
ASN A  62
ARG A  64
ASN A  73
TRP A  80
GLU A  83
 GAL  A 201 (-3.8A)
GAL  A 201 (-3.9A)
FUC  A 202 (-2.7A)
GAL  A 201 (-3.8A)
GAL  A 201 ( 3.8A)
FUC  A 202 (-2.7A)
 0.30A 3galB-3vv1A:
21.0		 3galB-3vv1A:
30.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		4 / 7 ARG A  46
VAL A  71
GLU A  83
ARG A  85
 FUC  A 202 ( 4.7A)
None
FUC  A 202 (-2.7A)
FUC  A 202 ( 4.1A)
 1.26A 4mv7A-3vv1A:
undetectable		 4mv7A-3vv1A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_A_5D5A930_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		5 / 12 LEU A  59
LEU A  38
HIS A 115
PRO A  89
PHE A  61
 None
 1.35A 5dlvA-3vv1A:
undetectable		 5dlvA-3vv1A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		4 / 8 HIS A  60
ASN A  62
HIS A  48
GLY A 135
 GAL  A 201 (-3.8A)
GAL  A 201 (-3.9A)
None
None
 0.92A 5m8rC-3vv1A:
undetectable		 5m8rC-3vv1A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		6 / 12 HIS A 115
PHE A 100
VAL A 101
TYR A  96
ILE A  95
VAL A  37
 None
 1.32A 5n0tA-3vv1A:
undetectable		 5n0tA-3vv1A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		7 / 7 HIS A  60
ASN A  62
ARG A  64
ASN A  73
TRP A  80
GLU A  83
ARG A  85
 GAL  A 201 (-3.8A)
GAL  A 201 (-3.9A)
FUC  A 202 (-2.7A)
GAL  A 201 (-3.8A)
GAL  A 201 ( 3.8A)
FUC  A 202 (-2.7A)
FUC  A 202 ( 4.1A)
 0.32A 6b8kA-3vv1A:
21.6		 6b8kA-3vv1A:
19.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		7 / 8 HIS A  60
ASN A  62
ARG A  64
ASN A  73
TRP A  80
GLU A  83
ARG A  85
 GAL  A 201 (-3.8A)
GAL  A 201 (-3.9A)
FUC  A 202 (-2.7A)
GAL  A 201 (-3.8A)
GAL  A 201 ( 3.8A)
FUC  A 202 (-2.7A)
FUC  A 202 ( 4.1A)
 0.49A 6b94A-3vv1A:
18.2		 6b94A-3vv1A:
31.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		7 / 10 HIS A  60
ASN A  62
ARG A  64
ASN A  73
TRP A  80
GLU A  83
ARG A  85
 GAL  A 201 (-3.8A)
GAL  A 201 (-3.9A)
FUC  A 202 (-2.7A)
GAL  A 201 (-3.8A)
GAL  A 201 ( 3.8A)
FUC  A 202 (-2.7A)
FUC  A 202 ( 4.1A)
 0.41A 6b94A-3vv1A:
18.2
6b94B-3vv1A:
18.1		 6b94A-3vv1A:
31.00
6b94B-3vv1A:
31.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		4 / 4 ARG A  64
GLU A  67
GLU A  83
ARG A  85
 FUC  A 202 (-2.7A)
FUC  A 202 (-2.9A)
FUC  A 202 (-2.7A)
FUC  A 202 ( 4.1A)
 0.55A 6fk2A-3vv1A:
21.7		 6fk2A-3vv1A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 3vv1 PROTEIN LEC-6
(Caenorhabditis
elegans) 		4 / 4 ARG A  85
GLU A  83
GLU A  67
ARG A  64
 FUC  A 202 ( 4.1A)
FUC  A 202 (-2.7A)
FUC  A 202 (-2.9A)
FUC  A 202 (-2.7A)
 1.00A 6fk2A-3vv1A:
21.7		 6fk2A-3vv1A:
21.64