SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vv3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 6 VAL A 167
VAL A 125
ASN A 126
ILE A 131
 None
 0.98A 1e06A-3vv3A:
undetectable		 1e06A-3vv3A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 12 GLY A 277
HIS A 274
VAL A 122
ALA A 276
ASN A 169
 None
 1.12A 1eqbA-3vv3A:
undetectable		 1eqbA-3vv3A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 12 GLY A 277
HIS A 274
VAL A 122
ALA A 276
ASN A 169
 None
 1.13A 1eqbB-3vv3A:
undetectable		 1eqbB-3vv3A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 12 GLY A 277
HIS A 274
VAL A 122
ALA A 276
ASN A 169
 None
 1.12A 1eqbC-3vv3A:
undetectable		 1eqbC-3vv3A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 12 GLY A 277
HIS A 274
VAL A 122
ALA A 276
ASN A 169
 None
 1.12A 1eqbD-3vv3A:
undetectable		 1eqbD-3vv3A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 8 LEU A  11
SER A 255
SER A 109
ASP A  58
 None
 1.14A 1ig3A-3vv3A:
2.4
1ig3B-3vv3A:
2.5		 1ig3A-3vv3A:
20.30
1ig3B-3vv3A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 7 ASP A  58
LEU A  11
SER A 255
SER A 109
 None
 1.20A 1ig3A-3vv3A:
2.4
1ig3B-3vv3A:
2.3		 1ig3A-3vv3A:
20.30
1ig3B-3vv3A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.86A 1jnoA-3vv3A:
undetectable		 1jnoA-3vv3A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.86A 1jnoB-3vv3A:
undetectable		 1jnoB-3vv3A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.70A 1jo3A-3vv3A:
undetectable		 1jo3A-3vv3A:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.70A 1jo3B-3vv3A:
undetectable		 1jo3B-3vv3A:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.93A 1jo4A-3vv3A:
undetectable		 1jo4A-3vv3A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.93A 1jo4B-3vv3A:
undetectable		 1jo4B-3vv3A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 8 THR A 316
ASN A 319
MET A 246
LEU A 222
 None
 1.09A 1lhvA-3vv3A:
undetectable		 1lhvA-3vv3A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 5 ASP A 245
VAL A 244
SER A 214
ASP A 219
 None
 1.49A 1n2xB-3vv3A:
undetectable		 1n2xB-3vv3A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.83A 1ng8A-3vv3A:
undetectable		 1ng8A-3vv3A:
4.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA8_0
(GRAMICIDIN A)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 4 GLY A 310
VAL A 313
TRP A 239
GLY A 240
 None
 1.22A 1ng8A-3vv3A:
undetectable		 1ng8A-3vv3A:
4.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.83A 1ng8B-3vv3A:
undetectable		 1ng8B-3vv3A:
4.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB8_0
(GRAMICIDIN A)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 4 GLY A 310
VAL A 313
TRP A 239
GLY A 240
 None
 1.22A 1ng8B-3vv3A:
undetectable		 1ng8B-3vv3A:
4.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.91A 1nrmA-3vv3A:
undetectable		 1nrmA-3vv3A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.91A 1nrmB-3vv3A:
undetectable		 1nrmB-3vv3A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.90A 1nruA-3vv3A:
undetectable		 1nruA-3vv3A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.90A 1nruB-3vv3A:
undetectable		 1nruB-3vv3A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.86A 1nt6A-3vv3A:
undetectable		 1nt6A-3vv3A:
3.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ALA A 114
VAL A 125
TRP A  34
 None
 0.85A 1nt6B-3vv3A:
undetectable		 1nt6B-3vv3A:
3.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 12 GLU A 102
ALA A 263
GLY A 105
GLY A 103
LEU A 137
 None
 0.98A 1x1aA-3vv3A:
undetectable		 1x1aA-3vv3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 8 VAL A 257
ASP A 100
TYR A 262
TYR A 265
 None
 1.03A 1z2bB-3vv3A:
2.6		 1z2bB-3vv3A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 7 ASN A 321
SER A 301
ALA A 327
VAL A 285
 None
 0.65A 3a2qA-3vv3A:
undetectable		 3a2qA-3vv3A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 5 ASN A  16
ARG A 317
ASN A 319
ALA A  30
 None
 1.42A 3frqA-3vv3A:
0.5		 3frqA-3vv3A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 7 ASN A  16
ARG A 317
ASN A 319
ALA A  30
 None
 1.39A 3frqB-3vv3A:
0.5		 3frqB-3vv3A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ASN A 218
MET A 155
PHE A 195
 None
 1.02A 3g4lD-3vv3A:
undetectable		 3g4lD-3vv3A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 LEU A  14
TRP A  12
GLY A 252
 None
 0.70A 3l35A-3vv3A:
undetectable
3l35H-3vv3A:
undetectable		 3l35A-3vv3A:
7.93
3l35H-3vv3A:
3.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 LEU A  14
TRP A  12
GLY A 252
 None
 0.74A 3l35B-3vv3A:
undetectable
3l35K-3vv3A:
undetectable		 3l35B-3vv3A:
7.93
3l35K-3vv3A:
3.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 5 GLY A 121
VAL A 120
ASP A  58
THR A 256
 None
 1.26A 3vqrB-3vv3A:
undetectable		 3vqrB-3vv3A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 12 ILE A 253
SER A 171
ILE A 224
PHE A 195
VAL A 167
 None
 1.08A 3w68B-3vv3A:
undetectable		 3w68B-3vv3A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 ASN A  80
ASP A  85
ASN A  66
 CA  A 401 (-3.1A)
CA  A 401 (-3.0A)
None
 0.71A 4agaA-3vv3A:
undetectable		 4agaA-3vv3A:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EBK_B_TOYB302_1
(AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 9 ASP A 231
GLU A  17
ALA A  24
GLU A  32
ASP A  29
 None
None
None
CA  A 402 ( 4.2A)
CA  A 403 ( 2.2A)
 1.40A 4ebkA-3vv3A:
0.5
4ebkB-3vv3A:
0.5		 4ebkA-3vv3A:
21.93
4ebkB-3vv3A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 7 ASP A 303
ASN A  16
GLU A  17
ASP A 231
 None
 1.16A 4fevB-3vv3A:
undetectable		 4fevB-3vv3A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 7 ASP A 303
ASN A  16
GLU A  17
ASP A 231
 None
 1.15A 4fewB-3vv3A:
undetectable		 4fewB-3vv3A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 8 ASP A 303
ASN A  16
GLU A  17
ASP A 231
 None
 1.16A 4gkhD-3vv3A:
undetectable		 4gkhD-3vv3A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 6 ASP A  27
ASN A  16
ALA A  24
ASP A 303
 CA  A 402 (-2.3A)
None
None
None
 1.09A 4mdbA-3vv3A:
undetectable		 4mdbA-3vv3A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 6 VAL A 320
SER A  35
ALA A   2
PHE A   8
 None
 1.13A 4nedA-3vv3A:
undetectable		 4nedA-3vv3A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 10 LEU A 222
VAL A 320
LEU A 324
LEU A 281
VAL A 285
 None
 1.21A 4po0A-3vv3A:
undetectable		 4po0A-3vv3A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 12 LEU A 298
GLY A 247
ALA A 248
ILE A  28
VAL A 125
 None
 0.83A 4xdrA-3vv3A:
undetectable		 4xdrA-3vv3A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		6 / 9 LEU A 289
ALA A 327
LEU A 297
ALA A 323
LEU A 298
ALA A 278
 None
 1.25A 4z91F-3vv3A:
undetectable
4z91G-3vv3A:
undetectable
4z91H-3vv3A:
undetectable
4z91I-3vv3A:
undetectable
4z91J-3vv3A:
undetectable		 4z91F-3vv3A:
23.80
4z91G-3vv3A:
23.80
4z91H-3vv3A:
23.80
4z91I-3vv3A:
23.80
4z91J-3vv3A:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 6 ALA A 271
THR A 272
VAL A 275
VAL A 244
 None
 0.88A 5eclA-3vv3A:
undetectable		 5eclA-3vv3A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 6 ALA A 271
THR A 272
VAL A 275
VAL A 244
 None
 0.78A 5eclD-3vv3A:
undetectable		 5eclD-3vv3A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 6 THR A  50
GLY A 105
TYR A 265
ILE A 253
 None
 0.90A 5kmfA-3vv3A:
undetectable
5kmfC-3vv3A:
undetectable		 5kmfA-3vv3A:
18.59
5kmfC-3vv3A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		4 / 8 PRO A 213
ALA A 182
ALA A 148
ILE A 149
 None
 0.76A 5mvmA-3vv3A:
undetectable
5mvmB-3vv3A:
undetectable		 5mvmA-3vv3A:
11.84
5mvmB-3vv3A:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 12 ILE A 224
VAL A 221
PHE A 195
SER A 223
ALA A 271
 None
 1.12A 5n0oA-3vv3A:
undetectable		 5n0oA-3vv3A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 12 ILE A 224
VAL A 221
PHE A 195
SER A 223
ALA A 271
 None
 1.06A 5n0sB-3vv3A:
undetectable		 5n0sB-3vv3A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		3 / 3 SER A 115
ALA A 114
THR A 256
 None
 0.64A 5n0xB-3vv3A:
undetectable		 5n0xB-3vv3A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 12 GLY A  13
ASP A  10
VAL A 122
GLY A 124
ILE A 253
 None
 0.89A 5t8hB-3vv3A:
undetectable		 5t8hB-3vv3A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 3vv3 DESEASIN MCP-01
(Pseudoalteromona
s
sp.
SM9913) 		5 / 10 ALA A  30
VAL A 125
ALA A 271
THR A 227
LEU A 318
 None
 1.49A 6h1lA-3vv3A:
undetectable		 6h1lA-3vv3A:
20.28