SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vvj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 9 ILE A 122
LEU A 322
VAL A  42
GLY A  45
LEU A 175
 None
 1.10A 1e7aB-3vvjA:
undetectable		 1e7aB-3vvjA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 9 ILE A 122
LEU A 322
VAL A  42
GLY A  45
LEU A 175
 None
 1.13A 1e7bA-3vvjA:
undetectable		 1e7bA-3vvjA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 12 GLY A 339
LEU A 233
VAL A 244
ALA A 338
PRO A 284
 None
 1.14A 1eqbA-3vvjA:
undetectable		 1eqbA-3vvjA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 12 GLY A 339
LEU A 233
VAL A 244
ALA A 338
PRO A 284
 None
 1.14A 1eqbC-3vvjA:
undetectable		 1eqbC-3vvjA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 11 PHE A 380
SER A 340
LEU A 283
VAL A 361
PHE A 365
 None
 1.34A 1q23G-3vvjA:
undetectable		 1q23G-3vvjA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 10 SER A  34
ILE A  35
LEU A 294
ASN A 293
ILE A 328
 None
 1.24A 2nnhB-3vvjA:
undetectable		 2nnhB-3vvjA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		4 / 8 MET A  54
LEU A 306
LEU A 175
GLY A 315
 None
 0.98A 2po5A-3vvjA:
undetectable		 2po5A-3vvjA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		4 / 5 PHE A 199
PHE A 359
SER A 356
PHE A 365
 None
 1.40A 2v0mD-3vvjA:
undetectable		 2v0mD-3vvjA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		4 / 8 ILE A  63
LEU A 125
ILE A   4
PHE A  60
 None
 0.70A 2w9sE-3vvjA:
undetectable		 2w9sE-3vvjA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 11 ILE A  58
ASN A 375
ILE A  63
THR A  76
LEU A  84
 None
 1.28A 3a50C-3vvjA:
undetectable		 3a50C-3vvjA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 12 ILE A  58
ASN A 375
ILE A  63
THR A  76
LEU A  84
 None
 1.18A 3a50E-3vvjA:
undetectable		 3a50E-3vvjA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		3 / 3 GLU A 337
HIS A 285
THR A 194
 None
 0.87A 3hkuA-3vvjA:
undetectable		 3hkuA-3vvjA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		4 / 6 VAL A 157
TYR A 180
TYR A 332
GLU A 334
 None
 1.24A 3q5sA-3vvjA:
undetectable		 3q5sA-3vvjA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 10 THR A 344
SER A 345
PHE A 161
SER A  31
VAL A 297
 None
 1.48A 3u9fE-3vvjA:
undetectable		 3u9fE-3vvjA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 12 THR A 344
SER A 345
PHE A 161
SER A  31
VAL A 297
 None
 1.42A 3u9fH-3vvjA:
undetectable
3u9fI-3vvjA:
undetectable		 3u9fH-3vvjA:
17.09
3u9fI-3vvjA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 12 THR A 344
SER A 345
PHE A 161
SER A  31
VAL A 297
 None
 1.47A 3u9fJ-3vvjA:
undetectable
3u9fL-3vvjA:
undetectable		 3u9fJ-3vvjA:
17.09
3u9fL-3vvjA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_O_CLMO221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 11 THR A 344
SER A 345
PHE A 161
SER A  31
VAL A 297
 None
 1.46A 3u9fM-3vvjA:
undetectable
3u9fO-3vvjA:
undetectable		 3u9fM-3vvjA:
17.09
3u9fO-3vvjA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		3 / 3 PHE A  43
SER A  69
SER A  77
 None
 1.01A 3ufgB-3vvjA:
undetectable		 3ufgB-3vvjA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		4 / 6 GLU A 151
ILE A 158
GLU A 326
VAL A 174
 None
 1.13A 4ejwB-3vvjA:
undetectable		 4ejwB-3vvjA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 12 LEU A 175
LEU A 306
ILE A 316
TYR A 118
ILE A 122
 None
 0.96A 4odrA-3vvjA:
undetectable
4odrB-3vvjA:
undetectable		 4odrA-3vvjA:
15.05
4odrB-3vvjA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		4 / 8 PHE A  43
SER A  77
GLU A  90
ASP A  86
 None
 1.05A 4qb9D-3vvjA:
undetectable		 4qb9D-3vvjA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		4 / 7 ILE A  36
LEU A  33
GLY A   5
LYS A   2
 None
 0.95A 4z69A-3vvjA:
undetectable		 4z69A-3vvjA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 12 LEU A  39
SER A  40
LEU A 294
ALA A 178
SER A  31
 None
 0.90A 5jglA-3vvjA:
undetectable		 5jglA-3vvjA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		3 / 3 MET A 279
GLU A 275
ARG A 277
 None
 1.12A 5tjyA-3vvjA:
undetectable		 5tjyA-3vvjA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		3 / 3 MET A 279
GLU A 275
ARG A 277
 None
 1.06A 5tjzA-3vvjA:
undetectable		 5tjzA-3vvjA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		5 / 9 LEU A 175
ILE A 122
GLY A 128
PHE A  60
ILE A   4
 None
 0.65A 5vkqC-3vvjA:
undetectable
5vkqD-3vvjA:
undetectable		 5vkqC-3vvjA:
13.18
5vkqD-3vvjA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 3vvj OVALBUMIN
(Dromaius
novaehollandiae) 		4 / 8 PHE A 380
ILE A 377
PHE A  13
THR A 269
 None
 0.89A 5x23A-3vvjA:
undetectable		 5x23A-3vvjA:
23.25