SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vvt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3vvt NUCLEOSIDE
DIPHOSPHATE KINASE
(-) 		4 / 7 ARG A 102
ILE A 114
ASN A 112
GLU A  51
 None
 1.12A 4a97E-3vvtA:
undetectable		 4a97E-3vvtA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3vvt NUCLEOSIDE
DIPHOSPHATE KINASE
(-) 		5 / 12 ARG A 102
ILE A 114
ASN A 112
GLU A  51
VAL A   6
 None
 1.40A 4a97A-3vvtA:
undetectable
4a97B-3vvtA:
undetectable		 4a97A-3vvtA:
19.37
4a97B-3vvtA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 3vvt NUCLEOSIDE
DIPHOSPHATE KINASE
(-) 		4 / 6 HIS A 115
GLU A 126
ASP A 118
SER A 122
 None
 1.24A 4apjA-3vvtA:
undetectable
4apjP-3vvtA:
undetectable		 4apjA-3vvtA:
14.43
4apjP-3vvtA:
9.90