SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vvw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3A_A_TEPA1436_1 (CHITINASE)	3vvw	CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	3 / 3	ASP A 111 PHE A 48 ARG A 117	None	0.60A	2a3aA-3vvwA: undetectable	2a3aA-3vvwA: 12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ATT_A_ACTA1209_0 (PUTATIVE UNCHARACTERIZED PROTEIN)	3vvw	CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	4 / 4	ASP A 111 ARG A 117 ASP A 54 GLU A 112	None	1.02A	3attA-3vvwA: 0.0	3attA-3vvwA: 15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C49_C_HCYC1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	3vvw	CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	5 / 12	VAL A 23 PHE A 107 ILE A 56 PHE A 25 HIS A 41	None	1.20A	4c49C-3vvwA: undetectable	4c49C-3vvwA: 14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Q1S_A_AWYA1103_0 (DNA CROSS-LINK REPAIR 1A PROTEIN)	3vvw	CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	4 / 6	VAL A 75 ILE A 79 LYS A 88 TYR A 42	None	1.40A	5q1sA-3vvwA: undetectable	5q1sA-3vvwA: 14.55

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2A3A_A_TEPA1436_1","CHITINASE","3vvw","CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2","Homo sapiens",3,"ASP A 111;PHE A  48;ARG A 117","None","0.60A","2a3aA-3vvwA:undetectable","2a3aA-3vvwA:12.53"],["3ATT_A_ACTA1209_0","PUTATIVE UNCHARACTERIZED PROTEIN","3vvw","CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2","Homo sapiens",4,"ASP A 111;ARG A 117;ASP A  54;GLU A 112","None","1.02A","3attA-3vvwA:0.0","3attA-3vvwA:15.21"],["4C49_C_HCYC1384_1","CORTICOSTEROID-BINDING GLOBULIN","3vvw","CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2","Homo sapiens",5,"VAL A  23;PHE A 107;ILE A  56;PHE A  25;HIS A  41","None","1.20A","4c49C-3vvwA:undetectable","4c49C-3vvwA:14.91"],["5Q1S_A_AWYA1103_0","DNA CROSS-LINK REPAIR 1A PROTEIN","3vvw","CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2","Homo sapiens",4,"VAL A  75;ILE A  79;LYS A  88;TYR A  42","None","1.40A","5q1sA-3vvwA:undetectable","5q1sA-3vvwA:14.55"]]