SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vw1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 109
ALA A  17
LEU A  54
ALA A  12
HIS A  61
 None
 1.08A 3ou6B-3vw1A:
undetectable		 3ou6B-3vw1A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 109
ALA A  17
LEU A  54
ALA A  12
HIS A  61
 None
 1.09A 3ou7C-3vw1A:
undetectable		 3ou7C-3vw1A:
21.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		9 / 12 TYR A  59
LEU A  66
THR A  85
ILE A  88
SER A  91
TYR A  92
ILE A 106
ALA A 110
LEU A 130
 None
 0.66A 3vw1B-3vw1A:
28.7		 3vw1B-3vw1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		9 / 12 TYR A  59
LEU A  66
THR A  85
ILE A  88
SER A  91
TYR A  92
ILE A 106
LEU A 130
PHE A 155
 None
 0.70A 3vw1B-3vw1A:
28.7		 3vw1B-3vw1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		9 / 12 TYR A  59
LEU A  66
THR A  85
SER A  91
TYR A  92
ILE A 106
ALA A 110
LEU A 130
LEU A 188
 None
 0.68A 3vw1B-3vw1A:
28.7		 3vw1B-3vw1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		9 / 12 TYR A  59
LEU A  66
THR A  85
SER A  91
TYR A  92
ILE A 106
LEU A 130
PHE A 155
LEU A 188
 None
 0.68A 3vw1B-3vw1A:
28.7		 3vw1B-3vw1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		9 / 12 TYR A  59
LEU A  66
THR A  85
SER A  91
TYR A  92
ILE A 106
PHE A 155
LEU A 156
LEU A 188
 None
 0.68A 3vw1B-3vw1A:
28.7		 3vw1B-3vw1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		10 / 12 LEU A  66
CYH A  67
THR A  85
ILE A  88
SER A  91
TYR A  92
ILE A 106
ALA A 110
CYH A 134
PHE A 155
 None
 0.78A 3vw1D-3vw1A:
29.8		 3vw1D-3vw1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		11 / 12 LEU A  66
CYH A  67
THR A  85
SER A  91
TYR A  92
ILE A 106
ALA A 110
CYH A 134
VAL A 138
ASP A 152
PHE A 155
 None
 0.68A 3vw1D-3vw1A:
29.8		 3vw1D-3vw1A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A  97
LEU A  62
LEU A  66
ALA A 101
ALA A 105
 None
None
None
SO4  A 201 (-3.4A)
None
 1.11A 3vw7A-3vw1A:
undetectable		 3vw7A-3vw1A:
17.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		7 / 12 LEU A  66
THR A  85
ILE A  88
TYR A  92
ALA A 110
ASP A 152
LEU A 156
 None
 0.64A 6ie8A-3vw1A:
27.3		 6ie8A-3vw1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 3vw1 PUTATIVE REGULATORY
PROTEIN
(Salmonella
enterica) 		7 / 12 LYS A  63
LEU A  66
THR A  85
ILE A  88
ALA A 110
ASP A 152
LEU A 156
 None
 0.75A 6ie8A-3vw1A:
27.3		 6ie8A-3vw1A:
100.00