SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vwc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_A_ASDA332_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3vwc SERINE PROTEASE
INHIBITOR 1
(Coprinopsis
cinerea) 		5 / 10 TRP A  47
THR A 105
SER A 104
VAL A 123
LEU A  72
 None
 1.49A 3casA-3vwcA:
undetectable		 3casA-3vwcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3vwc SERINE PROTEASE
INHIBITOR 1
(Coprinopsis
cinerea) 		5 / 12 GLY A  78
ASP A  75
ALA A  74
ARG A  21
GLU A  25
 None
 0.91A 3g8bB-3vwcA:
undetectable		 3g8bB-3vwcA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3vwc SERINE PROTEASE
INHIBITOR 1
(Coprinopsis
cinerea) 		4 / 5 SER A 104
ARG A 124
GLY A  70
GLU A 122
 None
 1.07A 5cdqA-3vwcA:
undetectable
5cdqB-3vwcA:
undetectable
5cdqC-3vwcA:
undetectable		 5cdqA-3vwcA:
13.65
5cdqB-3vwcA:
20.73
5cdqC-3vwcA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3vwc SERINE PROTEASE
INHIBITOR 1
(Coprinopsis
cinerea) 		4 / 5 SER A 104
ARG A 124
GLY A  70
GLU A 122
 None
 1.07A 5cdqR-3vwcA:
undetectable
5cdqS-3vwcA:
undetectable
5cdqT-3vwcA:
undetectable		 5cdqR-3vwcA:
13.65
5cdqS-3vwcA:
20.73
5cdqT-3vwcA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3vwc SERINE PROTEASE
INHIBITOR 1
(Coprinopsis
cinerea) 		4 / 8 GLN A  90
THR A  99
VAL A 100
SER A   2
 None
 1.15A 6fbvC-3vwcA:
undetectable		 6fbvC-3vwcA:
9.63